Catalog No.S2491

Nitrendipine is a dihydropyridine calcium channel blocker with an IC50 of 95 nM.

Price Stock Quantity  
In DMSO USD 130 In stock
USD 97 In stock
Bulk Inquiry

Massive Discount Available

Free Overnight Delivery on all orders over $ 500.

Nitrendipine Chemical Structure

Nitrendipine Chemical Structure
Molecular Weight: 360.3699

Validation & Quality Control

Quality Control & MSDS

Related Compound Libraries

Nitrendipine is available in the following compound libraries:

Product Information

  • Compare Calcium Channel Chemicals
    Compare Calcium Channel Products
  • Research Area

Product Description

Biological Activity

Nitrendipine is a dihydropyridine calcium channel blocker with an IC50 of 95 nM.It is an investigational dihydropyridine calcium-channel antagonist for the treatment of hypertension. Nitrendipine and BRL 38227 cause concentration-related inhibitions of the inositol phosphate response to histamine (100 µM). Similar maximal inhibitions were caused by each agent (55-58%). Inhibitory effect of BRL 38227 was reduced in potency (IC50 = 5.5 µM), but not magnitude, in the presence of glibenclamide (0.5 µM). [1][2]

Chemical Information

Download Nitrendipine SDF
Molecular Weight (MW) 360.3699


CAS No. 39562-70-4
Storage 3 years -20℃Powder
6 months-80℃in DMSO
Solubility (25°C) * In vitro DMSO 72 mg/mL (199 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Research Area

Tech Support & FAQs

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

* Indicates a Required Field

Related Calcium Channel Products

  • Selinexor (KPT-330)

    Selinexor (KPT-330) is an orally bioavailable selective CRM1 inhibitor. Phase 2.

  • KPT-185

    KPT-185 is a selective CRM1 inhibitor.

  • CFTRinh-172

    CFTRinh-172 is a voltage-independent, selective CFTR inhibitor with Ki of 300 nM, showing no effects on MDR1, ATP-sensitive K+ channels, or a series of other transporters.

  • Cilnidipine

    Cilnidipine is a calcium channel blocker.

  • Ranolazine 2HCl

    Ranolazine 2HCl, is an antianginal medication.

  • Amlodipine

    Amlodipine is a long-acting calcium channel blocker with an IC50 of 1.9 nM.

  • Isradipine

    Isradipine is a calcium channel blocker with an IC50 of 34±8 μM.

  • Manidipine 2HCl

    Manidipine 2HCl is a HCl salt form of Manidipine, which is a calcium channel blocker with IC50 of 2.6 nM, used clinically as an antihypertensive. Phase 4.

  • Nimodipine

    Nimodipine is a dihydropyridine derivative and an analogue of the calcium channel blocker nifedipine, with antihypertensive activity.Nimodipine decreases intracellular free Ca2+,Beclin-1 and autophagy.

  • Lacidipine

    Lacidipine is a L-type calcium channel blocker.

Recently Viewed Items

Tags: buy Nitrendipine | Nitrendipine ic50 | Nitrendipine price | Nitrendipine cost | Nitrendipine solubility dmso | Nitrendipine purchase | Nitrendipine manufacturer | Nitrendipine research buy | Nitrendipine order | Nitrendipine mouse | Nitrendipine chemical structure | Nitrendipine mw | Nitrendipine molecular weight | Nitrendipine datasheet | Nitrendipine supplier | Nitrendipine in vitro | Nitrendipine cell line | Nitrendipine concentration | Nitrendipine nmr
Contact Us