CRM1

Inhibitory Selectivity

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Notes:
2. For more details, such as half maximal inhibitory concentrations (IC50s) and working concentrations of each inhibitor, please click on the link of the inhibitor of interest.
3. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation.
4. Orange "√" refers to compounds which do inhibitory effects on the related isoform, but without specific value.

Catalog No. Information Product Use Citations Product Validations
S7252

Selinexor (KPT-330)

Selinexor (KPT-330) is an orally bioavailable selective CRM1 inhibitor. Phase 2.

S7125

KPT-185

KPT-185 is a selective CRM1 inhibitor.

S7251

KPT-276

KPT-276 is an orally bioavailable selective CRM1 inhibitor.

S7707

Verdinexor (KPT-335)

Verdinexor (KPT-335) is an orally bioavailable, selective XPO1/CRM1 inhibitor.

Catalog No. Information Product Use Citations Product Validations
S7252

Selinexor (KPT-330)

Selinexor (KPT-330) is an orally bioavailable selective CRM1 inhibitor. Phase 2.

S7125

KPT-185

KPT-185 is a selective CRM1 inhibitor.

S7251

KPT-276

KPT-276 is an orally bioavailable selective CRM1 inhibitor.

S7707

Verdinexor (KPT-335)

Verdinexor (KPT-335) is an orally bioavailable, selective XPO1/CRM1 inhibitor.