Gossypol

Catalog No.S2303

Gossypol is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes.

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Gossypol Chemical Structure

Gossypol Chemical Structure
Molecular Weight: 518.56

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Quality Control & MSDS

Related Compound Libraries

Gossypol is available in the following compound libraries:

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Product Description

Biological Activity

Gossypol is a polyphenolic aldehyde that permeates cells and acts as an inhibitor for several dehydrogenase enzymes. It has proapoptotic properties, probably due to the regulation of the Bax and Bcl2. It also reversibly inhibits calcineurin and binds to calmodulin. It inhibits replication of the HIV-1 virus. It is an effective protein kinase D inhibitor. It also causes low potassium levels, and thus causes temporary paralysis. LD50: Rats 1010mg/kg.

Chemical Information

Download Gossypol SDF
Molecular Weight (MW) 518.56
Formula

C30H30O8

CAS No. 303-45-7
Storage 3 years -20℃Powder
6 months-80℃in DMSO
Syonnyms N/A
Solubility (25°C) * In vitro DMSO mg/mL (<1 mM)
Water mg/mL (<1 mM)
Ethanol mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Name

Preparing Stock Solutions

Stock Solution (1ml DMSO) 1mM 10mM 20mM 30mM
Mass(mg) 0.51856 5.1856 10.3712 15.5568

Research Area

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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