Diltiazem HCl
Catalog No.S1865 Synonyms: RG 83606 HCl
Molecular Weight(MW): 450.98
Diltiazem HCl (Tiazac) is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions.
Purity & Quality Control
Choose Selective Calcium Channel Inhibitors
Biological Activity
| Description | Diltiazem HCl (Tiazac) is a benzothiazepine derivative with vasodilating action due to its antagonism of the actions of the calcium ion in membrane functions. | |
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Protocol
Solubility (25°C)
| In vitro | DMSO | 90 mg/mL (199.56 mM) |
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| Water | 90 mg/mL (199.56 mM) | |
| Ethanol | 4 mg/mL (8.86 mM) |
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Information
| Molecular Weight | 450.98 |
|---|---|
| Formula | C22H26N2O4S.HCl |
| CAS No. | 33286-22-5 |
| Storage | powder |
| Synonyms | RG 83606 HCl |
Bio Calculators
Molarity Calculator
Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).
Dilution Calculator
Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )
* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).
Molecular Weight Calculator
Enter the chemical formula of a compound to calculate its molar mass and elemental composition:
Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2
Instructions to calculate molar mass (molecular weight) of a chemical compound:
To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.
Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Molarity Calculator
Clinical Trial Information
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT02947711 | Active, not recruiting | Healthy Subjects | Eisai Co., Ltd.|Eisai Inc. | October 2016 | Phase 1 |
| NCT02807909 | Completed | Thrombosis | Bristol-Myers Squibb | July 2016 | Phase 1 |
| NCT02801305 | Active, not recruiting | Digital Ulcer of Scleroderma | Mohammad Ali Nazarinia|Shiraz University of Medical Sciences | June 2016 | Phase 2 |
| NCT02695992 | Recruiting | Atrial Fibrillation|Permanent Atrial Fibrillation | Asker & Baerum Hospital|Vestre Viken Hospital Trust|Helse Sor-Ost | February 2016 | Phase 4 |
| NCT02653872 | Completed | Healthy Subjects | AstraZeneca | January 2016 | Phase 1 |
| NCT02526888 | Completed | Healthy Subjects | Actelion | September 2015 | Phase 1 |
Tech Support
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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