phosphatase

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S1949 Menadione <1 mg/mL 34 mg/mL 34 mg/mL
S1857 Etidronate 41 mg/mL <1 mg/mL <1 mg/mL
S1514 Cyclosporine <1 mg/mL 100 mg/mL 100 mg/mL
S4007 Pentamidine isethionate 119 mg/mL 119 mg/mL <1 mg/mL
S7437 Sal003 <1 mg/mL 93 mg/mL <1 mg/mL
S8278 SHP099 dihydrochloride 77 mg/mL 2 mg/mL <1 mg/mL
S8182 NSC87877 100 mg/mL 100 mg/mL <1 mg/mL
S4013 Sodium Monofluorophosphate 29 mg/mL <1 mg/mL <1 mg/mL
S7485 CCT007093 <1 mg/mL 1 mg/mL <1 mg/mL
S7537 LB-100 53 mg/mL <1 mg/mL <1 mg/mL
S7383 (-)-p-Bromotetramisole Oxalate 30 mg/mL 74 mg/mL <1 mg/mL
S7573 GSK2830371 <1 mg/mL 92 mg/mL 92 mg/mL
Catalog No. Information Product Use Citations Product Validations
S1949

Menadione

Menadione(Vitamin K3), a fat-soluble compound, is an inhibitor of Cdc25 phosphatase and mitochondrial DNA polymerase γ (pol γ), used as a nutritional supplement.

S1857

Etidronate

Etidronate is a non-aminobisphosphonate, show protein tyrosine phosphatase (PTP) inhibitory activity, used for the treatment of Paget's disease and the prevention of heterotopic ossification.

S1514

Cyclosporine

Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation.

S4007

Pentamidine isethionate

Pentamidine is an inhibitor of PRL Phosphatases and also inhibits synthesis of DNA, RNA and protein.

S7437

Sal003

Sal003 is a potent and cell-permeable eIF-2α phosphatase inhibitor.

S8278New

SHP099 dihydrochloride

SHP099 is a highly potent, selective and orally bioavailable small-molecule SHP2 inhibitor with an IC50 value of 0.071 μM and shows no activity against SHP1.

S8182New

NSC87877

NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.

S4013

Sodium Monofluorophosphate

Sodium Monofluorophosphate is a competitive inhibitor of pyruvate kinase and alkaline phosphatase with Ki of 3.4 mM and 69 μM, respectively, which also irreversibly inhibits phosphorylase phosphatase with Ki of 0.5 mM.

S7485

CCT007093

CCT007093 is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 μM.

S7537

LB-100

LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.

S7383

(-)-p-Bromotetramisole Oxalate

(-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor.

S7573

GSK2830371

GSK2830371 is an orally active, allosteric Wip1 phosphatase inhibitor with IC50 of 6 nM.

Catalog No. Information Product Use Citations Product Validations
S1949

Menadione

Menadione(Vitamin K3), a fat-soluble compound, is an inhibitor of Cdc25 phosphatase and mitochondrial DNA polymerase γ (pol γ), used as a nutritional supplement.

S1857

Etidronate

Etidronate is a non-aminobisphosphonate, show protein tyrosine phosphatase (PTP) inhibitory activity, used for the treatment of Paget's disease and the prevention of heterotopic ossification.

S1514

Cyclosporine

Cyclosporine is a calcineurin phosphatase pathway inhibitor, used as an immunosuppressant drug to prevent rejection in organ transplantation.

S4007

Pentamidine isethionate

Pentamidine is an inhibitor of PRL Phosphatases and also inhibits synthesis of DNA, RNA and protein.

S7437

Sal003

Sal003 is a potent and cell-permeable eIF-2α phosphatase inhibitor.

S8278New

SHP099 dihydrochloride

SHP099 is a highly potent, selective and orally bioavailable small-molecule SHP2 inhibitor with an IC50 value of 0.071 μM and shows no activity against SHP1.

S8182New

NSC87877

NSC-87877 is a cell-permeable inhibitor of both SHP-1 and SHP-2 with IC50 values of 355 and 318 nM respectively. It also inhibits EGF-induced Erk1/2 activation in HEK293 cells and significantly reduces MDA-MB-468 cell viability/proliferation.

S4013

Sodium Monofluorophosphate

Sodium Monofluorophosphate is a competitive inhibitor of pyruvate kinase and alkaline phosphatase with Ki of 3.4 mM and 69 μM, respectively, which also irreversibly inhibits phosphorylase phosphatase with Ki of 0.5 mM.

S7485

CCT007093

CCT007093 is a potent PPM1D (WIP1) inhibitor with IC50 of 8.4 μM.

S7537

LB-100

LB-100 is a water soluble protein phosphatase 2A (PP2A) inhibitor with IC50s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells.

S7383

(-)-p-Bromotetramisole Oxalate

(-)-p-Bromotetramisole Oxalate is a potent and non-specific alkaline phosphatase inhibitor.

S7573

GSK2830371

GSK2830371 is an orally active, allosteric Wip1 phosphatase inhibitor with IC50 of 6 nM.

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