Research Area
Product Type
United States ( Change Country )
(-)-Huperzine A Chemical Structure
-Huperzine-A-chemical-structure-S2251.gif)
LY2140023 (LY404039)
LY404039 is a potent agonist of recombinant human mGlu2, mGlu3 receptors and rat neurons expressing native mGlu2/3 receptors with Ki of 149 nM, 92 nM and 88nM, respectively.
Celecoxib
COX-2 inhibitor,IC50=0.04uM
BMS-708163
BMS-708163 is a γ-secretase inhibitor (GSI) (IC50 =0.3 nM)
Asenapine
Asenapine is a new atypical antipsychotic used for the treatment of schizophrenia and acute mania associated with bipolar disorder .
Cetirizine Dihydrochloride
Cetirizine Dihydrochloride is an antihistamine.
Etodolac (Lodine)
Etodolac (Lodine) is a COX inhibitor with an IC50 of 53.5 nM.
Etomidate
Etomidate is a GABAA receptors agonist at GABAA receptors.
Flumazenil
Flumazenil is a benzodiazepine antagonist.
Fluoxetine
Fluoxetine is an antidepressant of the selective serotonin reuptake inhibitor (SSRI)class.
Galanthamine hydrobromide
Galanthamine hydrobromide is an effective, competitive and reversible acetylcholine esterase inhibitor.
Biological Activity
(-)-Huperzine A is an Acetylcholinesterase inhibitor and NMDA receptor antagonist with an IC50 of 126 μM for NMDA-induced current. Huperzine A, is a naturally occurring sesquiterpene alkaloid compound found in the plant firmoss Huperzia serrata. The IC(50) values of huperzine A were neither altered by changing the concentrations of glycine (2-0.2 μM) and pH (7.4-6.7) in the external solution, nor by addition of Zn(2+) (5 μM) and dithiothreitol (5 mM) to the external solution. [1][2]
References on (-)-Huperzine A
- [1] http://en.wikipedia.org/wiki/Huperzine_A ;
- [2] Neuroscience. 2001;105(3):663-9.
Product Information
| Molecular Weight (WM): | 242.32 |
|---|---|
| Formula: | C15H18N2O |
| CAS No.: | 102518-79-6 |
| Synonyms: |
N/A
|
| Dissolve in (25°C): | DMSO ≥49mg/mL |
| Water ≥49mg/mL | |
| Ethanol <1mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
Quality Control & MSDS
Research Area
Notes:
Related Inhibitors
Recommended Screening Libraries
Chemical Library
A collection of 864 bioactive compounds
Inhibitor Library
A collection of 481 inhibitors
Kinase Inhibitor Library
A collection of 194 kinase inhibitors
Tyrosine Kinase Inhibitor Library
A collection of 85 tyrosine kinase inhibitors.
FDA Approved Drug Library
A collection of 426 FDA approved drugs
Natural Product Library
A collection of 139 natural products
Chemotherapeutic Agent Library
A collection of 40 chemotherapeutic agents
Epigenetics Compound library
A unique collection of 17 small molecule modulators
Stem Cell Compound library
A unique collection of 47 small molecule inhibitors
GPCR Compound library
A unique collection of 63 GPCR small molecules
Keywords:buy (-)-Huperzine A | (-)-Huperzine A supplier | purchase (-)-Huperzine A | (-)-Huperzine A cost | (-)-Huperzine A manufacturer | order (-)-Huperzine A | (-)-Huperzine A distributor