Product Categories

New Products

Product Categories
PI3K/Akt/mTOR
JAK/STAT
Cell Cycle
DNA Damage
TGF-beta/smad
GPCR & G Protein
PTK
Epigenetics
NF-κB
Metabolism
Proteases
Microbiology
Apoptosis
MAPK
Angiogenesis
Stem Cell & Wnt
Ubiquitin
Neuronal Signaling
Others

PI3K/Akt/mTOR

water-soluble

Cat.No. Product Name Information
S7127 TIC10 TRAIL-inducing compound 10 (TIC10) is a potent, orally active, and stable small molecule that transcriptionally induces TRAIL in a p53-independent manner and crosses the blood-brain barrier.
S8063 SF1126 SF1126 is a soluble, vascular targeted pan-PI3K inhibitor.
S7103 GDC-0032  
S7063 LY2090314 LY2090314 is a potent GSK-3 inhibitor for GSK-3α and GSK-3β with IC50 of 1.5 nM and 0.9 nM, respectively.
S7064 FMK FMK is a potent, highly specific and irreversible inhibitor of p90 ribosomal protein S6 kinase RSK1and RSK2.
S8040 GDC-0349 GDC-0349, is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM.
S7028 IPI-145 (INK1197) IPI-145 (INK1197) is a novel and selective PI3K δ/γ inhibitor with Ki and IC50 of 23 pM/243 pM and 1 nM/50 nM.
S2163 PF-4708671 PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) with Ki of 20 nM and IC50 of 160 nM.
S8019 AZD5363 AZD5363 is a potent Akt inhibitor for Akt1, Akt2 and Akt3 with IC50 of 3 nM, 8 nM and 8 nM, respectively.
S8002 GSK2636771 GSK2636771 is a potent, orally bioavailable, PI3Kβ-selective inhibitor.

JAK/STAT

water-soluble

Cat.No. Product Name Information
S7144 BMS-911543 BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, approximately 350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively.
S7024 Stattic Stattic inhibits STAT3 with IC50 of 5.1 μM.
S8004 ZM 39923 HCl ZM39923 is an JAK inhibitor for JAK1, JAK3, EFGR and TGM2 with IC50 of 4.4 μM, 7.1 μM, 5.6 μM and 10 nM, respectively.
S8005 SMI-4a SMI-4a is a potent inhibitor of Pim1 with IC50 of 17 nM.
S2867 WHI-P154 WHI-P154 is a potent JAK3 inhibitor with IC50 of 1.8 μM and also inhibits EGFR with IC50 of 4 nM.
S2851 Baricitinib (LY3009104, INCB28050) Baricitinib is a selective JAK1 and JAK2 inhibitor with IC50 of 5.9 nM and 5.7 nM, respectively.
S2796 WP1066 WP1066 is a novel inhibitor of JAK2 and STAT3 with IC50 of 2.30 μM and 2.43 μM in HEL cells .
S2789 Tofacitinib (CP-690550, Tasocitinib) CP-690550 is a novel inhibitor of JAK3 with IC50 of 1 nM.
S2902 S-Ruxolitinib S-Ruxolitinib is a JAK family inhibitor for JAK1 and JAK2 with IC50 of 3.3 nM and 2.8 nM, respectively.
S2736 TG101348 (SAR302503) TG-101348 (SAR302503) is a selective inhibitor of JAK2 with IC50 of 3 nM.

Cell Cycle

water-soluble

Cat.No. Product Name Information
S7158 LY2835219  
S7153 10058-F4  
S7154 10074-G5  
S8058 P276-00 p276-00 is a novel CDK1, CDK4 and CDK9 inhibitor with IC50 of 79 nM, 63 nM and 20 nM, respectively.
S7047 BAY 1000394 BAY 1000394 is an orally bioavailable CDK inhibitor.
S1579 PD 0332991 (Palbociclib) Isethionate PD 0332991 (Palbociclib) Isethionate is the isethionate of PD 0332991, a highly specific inhibitor of CDK4 and CDK6 with IC50 of 11 nM and 16 nM, respectively.
S8031 NSC 23766 NSC 23766 is an inhibitor of Rac GTPase targeting Rac activation by guanine nucleotide exchange factors (GEFs) with IC50 of about 50 μM.
S2768 Dinaciclib (SCH727965) Dinaciclib (SCH727965) is a novel and potent CDK inhibitor for CDK2, CDK5, CDK1 and CDK9 with IC50 of 1 nM, 1 nM, 3 nM and 4 nM, respectively.
S2014 BMS-265246 BMS265246 is a potent and selective CDK inhibitor for CDK1/cyclin B and CDK2/cyclin E with IC50 of 6 nM and 9 nM, respectively.
S2770 MK-5108 (VX-689) MK-5108 (VX-689) is a highly selective Aurora A inhibitor with IC50 of 0.064 nM.

DNA Damage

water-soluble

Cat.No. Product Name Information
S8043 Scriptaid Scriptaid is an inhibitor of HDAC.
S4119 Pefloxacin Mesylate Dihydrate Pefloxacin Mesylate Dihydrate is the third generation of fluoroquinolone class of antibacterials, which inhibits Topoisomerase II activity and DNA replication.
S4125 Sodium Phenylbutyrate Sodium Phenylbutyrate is a transcriptional regulators that act by altering chromatin structure via the modulation of HDAC activity.
S7029 AZD2461 AZD2461 is a novel PARP inhibitor with potential to bypass Pgp-mediated resistance to Olaparib.
S7048 BMN 673 BMN 673 is a novel PARP inhibitor with IC50 of 0.58 nM.
S4908 SN-38 SN-38 is an active metabolite of CPT-11 that inhibits DNA topoisomerase I.
S8038 UPF 1069 UPF 1069 is a selective PARP2 inhibitor with IC50 of 0.3 μM.
S8007 VE-821 VE-821 is a potent and selective ATP competitive inhibitor of ATR with Ki and IC50 of 13 nM and 26 nM, respectively.
S2886 PJ34 PJ-34 is a potent PARP inhibitor with EC50 of 20 nM.
S2871 T0070907 T0070907 is a potent and selective PPARγ inhibitor with IC50 of 1 nM.

TGF-beta/smad

water-soluble

Cat.No. Product Name Information
S4066 Dequalinium Chloride Dequalinium Chloride is a PKC inhibitor with IC50 of 7-18 μM, and also a selective blocker of apamin-sensitive K+ channels with IC50 of 1.1 μM.
S2791 Sotrastaurin (AEB071) Sotrastaurin (AEB071) is a potent selective pan-PKC inhibitor and highly inhibits PKCθ with Ki of 0.22 nM.
S2186 SB-505124 SB505124 is a selective inhibitor of ALK4 and ALK5 with IC50 of 129 nM and 47 nM, respectively.
S2704 LY2109761 LY2109761 is a novel selective TGF-β receptor type I/II (TβRI/II) dual inhibitor with Ki of 38 nM and 300 nM, respectively.
S2750 GW788388 GW788388 is a potent and selective inhibitor of ALK5 with IC50 of 18 nM.
S2911 Go 6983 Go 6983 is a pan PKC inhibitor against PKCα, PKCβ, PKCγ, PKCδ, PKCζ with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM, respectively.
S2907 Pirfenidone Pirfenidone inhibits TGF-β bioactivity by affecting TGF-β2 mRNA expression and processing of pro-TGF-β in CCL-64 cells.
S2805 LY364947 LY364947 is a potent ATP-competitive inhibitor of TGFβR-I with IC50 of 59 nM.
S2618 LDN193189 LDN193189 is a selective inhibitor of ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively.
S2230 LY2157299 LY2157299 is a potent TGFβ receptor I (TβRI) inhibitor with IC50 of 56 nM.

GPCR & G Protein

water-soluble

Cat.No. Product Name Information
S7175 SK1-I (BML-258) SK1-I (BML-258) is a selective Sphingosine kinase 1 (SphK1, SK1) inhibitor with Ki of 10 µM.
S7177 PF-543 PF-543 is a novel Sphingosine kinase 1 (SphK1, SK1) inhibitor with Ki of 3.6 nM.
S8067 Vorapaxar  
S4127 Terbutaline Sulfate Terbutaline Sulfate is a selective β2-adrenergic receptor agonist with IC50 of 53 nM.
S8051 Macitentan Macitentana (Actelion-1, ACT-064992) is an orally active, non-peptide dual endothelin (ET)A/B receptor antagonist with IC50 of 0.5 nM/391 nM.
S8022 Empagliflozin (BI10773) Empagliflozin (BI-10773) is a potent and selective SGLT2 inhibitor with IC50 of 3.1 nM.
S4076 Propranolol HCl Propranolol HCl is a competitive non-selective beta-adrenergic receptors inhibitor with IC50 of 12 nM.
S8030 Plerixafor (AMD3100) Plerixafor is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively.
S8012 Otenabant (CP-945598) HCl CP-945598 HCl is a potent and selective cannabinoid type 1 receptor antagonist with Ki of 0.7 nM.
S3051 Bosentan Hydrate Bosentan is an endothelin (ET) receptors antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.

PTK

water-soluble

Cat.No. Product Name Information
S7083 LDK378 LDK378 is an orally available ALK inhibitor with IC50 of 0.15 nM.
S7039 PD168393  
S4911 BMS-690514 BMS-690514 is a potent inhibitor of EGFR and VEGFR2 with IC50 of 5 nM and 50 nM, respectively.
S8042 GW2580 GW2580 is a selective inhibitor of human c-FMS with IC50 of 30 nM.
S7067 EMD 1214063 EMD 1214063 is a potent and selective c-Met inhibitor with IC50 of 6 nM.
S4001 Cabozantinib malate Cabozantinib malate is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM, respectively.
S8024 Tyrphostin AG 1296 (AG 1296) Tyrphostin AG 1296 (AG 1296) is an inhibitor of PDGFR, FGFR and c-Kit with IC50 of < 1 μM, 12.3 μM and 1.8 μM, respectively.
S7000 AP26113 AP26113 is a potent ALK inhibitor for ALK, FER, ROS/ROS1, FLT3 and FES/FPS with IC50 of 0.62 nM, 1.3 nM, 1.9 nM, 2.1 nM and 3.4 nM, respectively.
S8009 AG 18 (Tyrphostin 23) AG 18 inhibits EGFR with IC50 of 35 μM.
S8003 PQ 401 PQ 401 is an IGF-1R inhibitor with IC50 of <1 μM.

Epigenetics

water-soluble

Cat.No. Product Name Information
S8049 Tubastatin A Tubastatin A is a potent and selective inhibitor of HDAC6 with IC50 of 15 nM.
S7113 Zebularine Zebularine is an inhibitor of cytidine deaminase and also inhibit DNA methylation.
S7120 3-Deazaneplanocin A (DZNeP) 3-deazaneplanocin A (DZNeP), an analog of adenosine, is a competitive inhibitor of S-adenosylhomocysteine hydrolase with Ki of 50 pM.
S7032 EPZ004777  
S7110 (+)-JQ1 (+)-JQ1 is a BET bromodomain inhibitor, inhibits binding of a tetraacetylated the bromodomain 1/2 of BRD4 with IC50 of 77 nM and 33 nM, respectively.
S7070 GSK J4 HCl GSK J4 HCl is a cell permeable prodrug of GSK J1, which is the first selective inhibitor of the H3K27 histone demethylase JMJD3/UTX with IC50 of 60 nM.
S7062 EPZ-5676 EPZ-5676 is an S-adenosyl methionine (SAM) competitive inhibitor of DOT11L with Ki of 80 pM.
S7079 SGC 0946 SGC 0946 is a highly potent and selective DOT1L methyltransferase inhibitor with IC50 of 0.3 nM.
S7013 SGI-110 SGI-110 is a second generation DNA-hypomethyating agent.
S4909 Apicidin (OSI-2040) Apicidin is a potent HDAC inhibitor with IC50 of 0.7 nM.

NF-κB

water-soluble

Cat.No. Product Name Information
S4073 Sodium 4-Aminosalicylate Sodium 4-Aminosalicylate is an antibiotic used to treat tuberculosis via NF-κB inhibition and free radical scavenging.
S4902 QNZ (EVP4593) QNZ is an inhibitor of NF-κB activation with IC50 of 11 nM.
S4907 SC-514 SC-514 is an orally active, ATP-competitive IKK-2 inhibitor with IC50 of 3-12 μM.
S2913 BAY 11-7082 (BAY 11-7821) Bay 11-7082 inhibits TNFα-induced IκBα phosphorylation with IC50 of 10 μM.
S2864 IMD 0354 IMD-0354 is an IKKβ inhibitor and blocks IκBα phosphorylation in NFκβ pathway.
S2863 ML130 ML130 is a potent and selective inhibitor of NOD1 with IC50 of 0.56 μM.
S2882 IKK-16 IKK 16 is a selective IκB kinase (IKK) inhibitor for IKK-2, IKK complex and IKK-1 with IC50 of 40 nM, 70 nM and 200 nM, respectively.
S2824 TPCA-1 TPCA-1 is an inhibitor of IKK-2 with IC50 of 17.9 nM.

Metabolism

water-soluble

Cat.No. Product Name Information
S4130 Mildronate Mildronate is an inhibitor of biosynthesis of L-carnitine by gamma-butyrobetaine (GBB) hydroxylase and as a competitive inhibitor of renal carnitine reabsorption.
S8025 GSK3787 GSK3787 is as a potent and selective antagonist of PPARδ with pIC50 of 6.6.
S8029 WY 14643 (Pirinixic Acid) WY 14643 (Pirinixic Acid) is a potent peroxisome proliferator and activator of PPARα with ED50 of 1.5 μM.
S8034 Apremilast (CC-10004) Apremilast (CC-10004) is a potent PDE4 and TNF-α inhibitor with IC50 of 74 nM and 77 nM, respectively.
S4039 Methazolamide Methazolamide is a carbonic anhydrase inhibitor with Ki of 50 nM, 14 nM and 36 nM for hCA I, hCA II and bCA IV isoforms, respectively.
S4019 Avanafil Avanafil is a highly selective PDE5 inhibitor with IC50 of 1 nM.
S4021 Tolcapone Tolcapone is a selective, potent and reversible of catechol-O-methyl transferase (COMT) inhibitor with Ki of 30 nM.
S2921 PF-4981517 PF-4981517 is a potent and selective inhibitor of CYP3A4 (P450) with IC50 of 0.03 μM.
S2900 Cobicistat (GS-9350) Cobicistat (GS-9350) is a potent and selective inhibitor of CYP3A with IC50 of 30-285 nM.
S8020 GW0742 GW0742 is a potent and highly selective PPARβ/δ agonist, binding to hPPARδ with IC50 of 1 nM.

Proteases

water-soluble

Cat.No. Product Name Information
S7172 ONX-0914 (PR-957) ONX-0914 (PR-957) is a potent and selective immunoproteasome inhibitor with minimal cross-reactivity for the constitutive proteasome.
S7155 BB-94  
S7156 Marimastat  
S7157 GM6001  
S8066 Salinosporamide A (NPI-0052, Marizomib)  
S7038 Epoxomicin (BU-4061T) Epoxomicin potently inhibits the chymotrypsin-like activity of the 20S proteasome.
S7049 Oprozomib (ONX 0912) Oprozomib (ONX 0912) selectively inhibits CT-L activity of 20S proteasome β5/LMP7 with IC50 of 36 nM/82 nM.
S2874 Camostat Mesilate (FOY-305) Camostat is a trypsin-like protease inhibitor, inhibiting matriptase and human neutrophil elastase with IC50 of 0.5 μM and 0.2 μM, respectively.
S3031 Linagliptin (BI-1356) Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM.
S3017 Aspirin (Acetylsalicylic acid) Aspirin is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication.

Microbiology

water-soluble

Cat.No. Product Name Information
S3080 Etravirine (TMC125) Etravirine (TMC125) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used for the treatment of HIV.
S2765 MK-2048 MK-2048 is an potent inhibitor of integrase (IN) and INR263K with IC50 of 2.6 nM and 1.5 nM, respectively.
S2579 Zidovudine (Retrovir) Zidovudine (Retrovir) is a reverse transcriptase inhibitor.
S2914 Dapivirine Dapivirine is an nonnucleoside reverse transcriptase inhibitor for HIV reverse transcriptase with IC50 of 24 nM.
S3165 Abacavir sulfate Abacavir is a commonly used nucleoside analogue with potent antiviral activity against HIV-1.
S2667 S/GSK1349572 (GSK1349572) S/GSK1349572 (GSK1349572) is a two-metal-binding HIV integrase inhibitor with IC50 of 2.7 nM.
S1704 Emtricitabine (Emtriva) Emtricitabine (Emtriva) is a nucleoside reverse transcriptase inhibitor with an IC50 of 27.7 μM.
S1742 Nevirapine(Viramune) Nevirapine(Viramune) is a non-nucleoside reverse transcriptase inhibitor (NNRTI) used to treat HIV-1 infection and AIDS.
S1719 Zalcitabine Zalcitabine is a nucleoside analog HIV reverse transcriptase inhibitor (NARTI).
S1706 Lamivudine (Epivir) Lamivudine(Epivir) is a potent nucleoside analog reverse transcriptase inhibitor with an IC50 of 2.7 mM.

Apoptosis

water-soluble

Cat.No. Product Name Information
S8061 Sabutoclax Sabutoclax(BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively.
S7023 Z-VAD-FMK Z-VAD-FMK is a cell-permeable, irreversible pan-caspase inhibitor, blocks all features of apoptosis.
S8048 ABT-199 (GDC-0199 ) ABT-199 is a Bcl-2-selective inhibitor with Ki < 0.010 nM.
S7015 Birinapant (TL32711) Birinapant (TL32711) is a SMAC mimetic and inhibitor of IAP family proteins.
S7034 BM-1074 BM-1074 is a potent and efficacious Bcl-2/Bcl-xL inhibitor with Ki of <1 nM.
S8037 Necrostatin-1 Necrostatin-1 is a specific RIP1 inhibitor and inhibits TNF-α-induced necroptosis with EC50 of 490 nM.
S2927 Apoptosis Activator 2 Apoptosis Activator 2 activates caspases in a cytochrome c-dependent manner and induces apoptosis in tumor cells.
S8000 Tenovin-1 Tenovin-1 is a p53 activator and acts through inhibition of protein-deacetylating activities of SirT1 and SirT2.
S2781 RITA (NSC 652287) RITA (NSC 652287) is a DNA damaging agent with IC50 of 2 nM and 20 nM in A498 and TK-10 cells.
S2738 PAC-1 PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM.

MAPK

water-soluble

Cat.No. Product Name Information
S7101 SCH772984  
S7121 MLN2480 MLN-2480 (BIIB-024) is a pan-Raf inhibitor.
S7001 PF-04880594 PF-04880594 is a RAF inhibitor for BRAF and c-RAF with IC50 of 0.19 nM and 0.39 nM, respectively.
S4901 JNK-IN-8 JNK-IN-8 is the first irreversible JNK inhibitor for JNK1, JNK2 and JNK4 with IC50 of 4.7 nM, 18.7 nM and 1 nM, respectively.
S2872 GW5074 GW5074 is a potent and selective c-Raf inhibitor with IC50 of 9 nM.
S8015 CEP-32496 CEP-32496 is a RAF inhibitor for BRAF(V600E), BRAF(WT), c-Raf, Abl-1 and CSF-1R with IC50 of 14 nM, 36 nM, 39 nM, 3 nM and 9 nM, respectively.
S2807 Dabrafenib (GSK2118436) Dabrafenib (GSK2118436) is a potent ATP-competitive inhibitor of B-Raf, B-RafV600E and c-Raf with IC50 of 3.2 nM, 0.8 nM and 5.0 nM, respectively.
S2746 AZ628 AZ628 is a potent inhibitor for wild-type CRAF and BRAFV600E with IC50 of 29 nM and 34 nM, respectively.
S2928 TAK 715 TAK 715 is a p38 MAPK inhibitor for p38α with IC50 of 7.1 nM.
S2726 PH-797804 PH-797804 is a novel pyridinone inhibitor of p38α with IC50 of 26 nM.

Angiogenesis

water-soluble

Cat.No. Product Name Information
S7008 PP2 PP2 is Src kinase inhibitor, potently inhibits GST-Src activity with IC50 of 100 nM.
S7022 GDC-0834  
S8032 PRT062607 (P505-15, PRT2607, BIIB057) HCl  
S8023 TCS 359 TCS 359 is a potent FLT3 inhibitor with IC50 of 42 nM.
S2018 ENMD-2076 L-(+)-Tartaric acid ENMD-2076 L-(+)-Tartaric acid is the tartaric acid of ENMD-2076, a selective inhibitor of Aurora A and Aurora B with IC50 of 14 nM and 350 nM and also inhibits Flt3, Flt4 and VEGFR2 with IC50 of 1.86 nM, 15.9 nM and 58.2 nM, respectively.
S2899 GNF-2 GNF-2 is a highly selective non-ATP competitive inhibitor of Bcr-Abl, inhibiting the proliferation of the Bcr-Abl-expressing cells with IC50 of 138 nM.
S2801 AZD4547 AZD4547 is a novel selective FGFR inhibitor targeting FGFR1, FGFR2, and FGFR3 with IC50 of of 0.2 nM, 2.5 nM, and 1.8 nM, respectively.
S3026 Piceatannol Piceatannol is a selective Syk inhibitor with IC50 of ~10 μM.
S1007 FG-4592 FG-4592 is an HIF α prolyl hydroxylase inhibitor.
S2183 BGJ398 (NVP-BGJ398) BGJ398 (NVP-BGJ398) is a potent and selective inhibitor of FGFR1, FGFR2 and FGFR3 with IC50 of 0.9 nM, 1.4 nM and 1 nM, respectively.

Stem Cell & Wnt

water-soluble

Cat.No. Product Name Information
S7168 LY900009 LY900009 is a potent Notch inhibitor with IC50 of 0.27 nM.
S7169 LY3039478 LY3039478 is a potent Notch inhibitor with IC50 of 0.41 nM.
S7096 KY02111 KY02111 promotes differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling.
S7085 IWP-2 IWP-2 is an inhibitor of Wnt processing and secretion with IC50 of 27 nM.
S7086 IWR-1-endo IWR-1 (endo-IWR 1) is a Wnt pathway inhibitor with IC50 of 180 nM.
S2777 PF-5274857 PF-5274857 is a potent and selective Smoothened (Smo) antagonist with IC50 and Ki of 5.8 nM and 4.6 nM, respectively.
S2662 ICG-001 ICG-001 specifically binds to CBP with IC50 of 3 μM.
S2157 LY2940680 LY2940680 binds to the Smo receptor and potently inhibits Hh signaling.
S2151 LDE225 (NVP-LDE225, Erismodegib) LDE225 (NVP-LDE225) is a smoothened antagonist with IC50 of 1.3 nM (mouse) and 2.5 nM (human), respectively.
S1180 XAV-939 XAV-939 is a selective Wnt β-catenin-mediated transcription inhibitor for TNKS1 and TNKS2 with IC50 of 11 nM and 4 nM, respectively.

Ubiquitin

water-soluble

Cat.No. Product Name Information
S4081 Sulfacetamide Sodium Sulfacetamide Sodium is an anti-biotic.
S1835 Azithromycin (Zithromax) Azithromycin (Zithromax) is an antibiotic for inhibition of parasite growth with IC50 of 8.4 μM.
S3201 Trifluoperazine 2HCl Trifluoperazine is a dopamine D2 receptor inhibitor with IC50 of 1.1 nM.
S2341 Parthenolide ((-)-Parthenolide) Parthenolide ((-)-Parthenolide) is a sesquiterpene lactone which occurs naturally in the plant feverfew(Tanacetum parthenium) and also promotes the ubiquitination of MDM2 and activates p53 cellular functions.
S1703 Divalproex sodium Divalproex sodium consists of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form.
S1237 Temozolomide Methazolastone (Temozolomide, Temodar, Temodal) is a DNA damage inducer.
S1193 Thalidomide Thalidomide was introduced as a sedative drug,immunomodulatory agent and also is investigated for treating symptoms of many cancers.Thalidomide inhibits an E3 ubiquitin ligase， which is a CRBN-DDB1-Cul4A complex.

Neuronal Signaling

water-soluble

Cat.No. Product Name Information
S4139 Cyclizine 2HCl  
S4140 Buclizine HCl  
S4118 Histamine 2HCl Histamine is an organic nitrogen compound, acts on target cells in mammalian brain via stimulation of Histamine 1/2.
S4121 Succinylcholine (Suxamethonium) Chloride Dihydrate Suxamethonium is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.
S4123 Timolol Maleate Timolol Maleate is a non-selective, beta-adrenergic receptor antagonist for β1/β2 with Ki of 1.97 nM/2.0 nM.
S4124 Tolazoline HCl Tolazoline is a non-selective competitive α-adrenergic receptor antagonist.
S4131 Levodropropizine Levodropropizine possess anti-allergic and inhibits histamine receptor, reduces cough by interfering with stimulus activation of peripheral endings of sensory nerves and by modulation of neuropeptides involved in the cough reflex.
S7118 AZD3839  
S4109 Lorcaserin HCl Lorcaserin HCl is a selective full agonist of human 5-HT2C receptor with Ki of 15 nM.
S4112 Desvenlafaxine Succinate Desvenlafaxine Succinate is a new serotonin (5-HT) transporter and norepinephrine (NE) transporter reuptake inhibitor with Ki of 40.2 nM and 558.4 nM respectively.

Others

water-soluble

Cat.No. Product Name Information
S7159 OTSSP167  
S7150 VER 155008  
S4141 Dinitolmide (Zoalene)  
S4142 Clopidol  
S4143 Pentoxyverine (Carbetapentane) Citrate  
S4144 Amprolium HCl  
S4145 Decoquinate  
S4146 Bacitracin  
s4147 Azithromycin Dihydrate  
S4148 Ampicillin Trihydrate