New Sodium Channel Chemicals

Catalog No.	Product Name	Information
E6460	Phenamil methanesulfonate	Phenamil methanesulfonate, is a potent and less reversible inhibitor of epithelial sodium channel (ENaC) with an IC50 of 400 nM. Phenamil methanesulfonate is also a competitive inhibitor of TRPP3 and inhibits TRPP3-mediated Ca2+ transport with an IC50 of 140 nM in a Ca2+ uptake assay. Phenamil methanesulfonate is used for the research of cystic fibrosis lung disease.
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