New Sirtuin Inhibitors & Activators

Cat.No. Product Name Information
S8628 3-TYP 3-TYP is a selective inhibitor of SIRT3 which is selective for Sirt3 over Sirt1 and Sirt2. The IC50 values for SITR1, SIRT2, SIRT3 are 88 nM, 92 nM, 16 nM respectively.
S8481 SRT3025 HCl SRT3025 is an orally available small molecule activator of the SIRT1 enzyme.
S8245 Thiomyristoyl Thiomyristoyl is a potent and specific SIRT2 inhibitor with an IC50 of 28 nM. It inhibits SIRT1 with an IC50 value of 98 μM and does not inhibit SIRT3 even at 200 μM.
S8460 Salermide Salermide is a reverse amide with a strong in vitro inhibitory effect on Sirt1 and Sirt2. Compared with Sirt1, Salermide is even more efficient at inhibiting Sirt2.
All Sirtuin Inhibitors & Activators