| Cat.No. |
Product Name |
Information |
|
S8489
|
GSK180736A (GSK180736) |
GSK180736A, developed as a Rho-associated, coiled-coil-containing protein kinase inhibitor, binds to GRK2(G protein-coupled receptor kinase 2) with logIC50 pf -6.6 (logIC50 -4.0 for GRK5 and >-3 for GRK1); ≥400-fold selective for GRK2 over both GRK1 and GRK5. |
|
S8208
|
Hydroxyfasudil (HA-1100) HCl |
Hydroxyfasudil (HA-1100), an active metabolite of fasudil hydrochloride, is a specific Rho-kinase(ROCK) inhibitor with IC50 values of 0.73 μM and 0.72 μM for ROCK1 and ROCK2, respectively. |
|
S8448
|
ZINC00881524 (ROCK inhibitor) |
ZINC00881524 is a ROCK inhibitor. |
|
S7935
|
Y-39983 HCl |
Y-39983 is a selective rho-associated protein kinase(ROCK) inhibitor with an IC50 of 3.6 nM. |
|
S8226
|
Netarsudil (AR-13324) 2HCl |
Netarsudil (a.k.a. AR-13324) is ROCK inhibitor with Ki value of 0.2-10.3 nM. It is currently in clinical trials for the treatment of glaucoma and ocular hypertension. |
| ≡ All ROCK Inhibitors |
