New Microtubule Associated Inhibitors

Catalog No. Product Name Information
E8284 PM534 PM534 is a potent microtubule-targeting agent (MTA) that binds the colchicine-binding domain (CBD) and inhibits tubulin assembly with IC50 values ranging from 0.8 to 3.2 nM. It also significantly inhibits tumor growth in mouse xenograft models of human non-small cell lung cancer.
S6772 VERU-111 Sabizabulin (VERU-111, ABI-231) is a potent, orally bioavailable inhibitor of tubulin that binds to the colchicine binding site. It inhibits the expression of β tubulin (III, IV) and α tubulin, with the potential to treat prostate cancer. It also exhibits significant anti-proliferative activity, with an average IC50 of 5.2 nM across a broad panel of cancer cell lines.
F0548 MAP2 Rabbit mAb MAP2,MAP-2,Microtubule-Associated Protein 2 (MAP2)
F2687 γ-Tubulin mAb gamma Tubulin,gamma-Tubulin,γ Tubulin,γ-Tubulin
F2614 Phospho-Tau (Ser 199) Rabbit mAb Phospho-Tau (Ser199),Tau (phospho S199)
All Microtubule Associated Inhibitors