New HSP (HSP90) Inhibitors

Catalog No. Product Name Information
E4678 EZH2/HSP90-IN-29 EZH2/HSP90-IN-29 is a potent dual inhibitor of EZH2 and HSP90, with IC50s of 6.29 nM and 60.1 nM, for EZH2 and HSP90, respectively, that induces M-phase cell cycle arrest, promotes apoptosis/necrosis-related gene expression, and inhibits ROS catabolism. It crosses the blood-brain barrier and can show potential as a tractable anti-GBM agent for glioblastoma research.
E5996 Col003 Col003 is a potent inhibitor of Hsp47 that competitively binds to the collagen-binding site on Hsp47 and inhibited the interaction between Hsp47 and collagen with an IC50 of 1.8 μM. It can be used in research as a potential lead compound for the treatment of fibrosis.
F0283 HSP90 Rabbit mAb Heat Shock Protein 90,HSP90,HSP90 alpha/beta
F2702 GRP78/BIP mAb BiP,BiP/GRP78,GRP78 BiP,GRP78/HSPA5,HSPA5,HSPA5/BiP/GRP78
F0607 SRC-3 Rabbit mAb SRC3,SRC-3
All HSP (HSP90) Inhibitors