MAO

Sigaling Pathway Map

Research Area

  • Inhibitory Selectivity
  • Solubility
Catalog No. Product Name Solubility(25°C)
Water DMSO Alcohol
S1472 Safinamide Mesylate 80 mg/mL 80 mg/mL 13 mg/mL
S2102 Rasagiline Mesylate 53 mg/mL 53 mg/mL 53 mg/mL
S4246 Tranylcypromine (2-PCPA) HCl 33 mg/mL 33 mg/mL 33 mg/mL
S3212 Moclobemide (Ro 111163) <1 mg/mL 53 mg/mL 10 mg/mL
S4717 Isatin <1 mg/mL 29 mg/mL 10 mg/mL
S2339 Paeonol <1 mg/mL 33 mg/mL 33 mg/mL

Isoform-specific Inhibitors

Catalog No. Information Product Use Citations Product Validations
S1472

Safinamide Mesylate

Safinamide Mesylate is mesylate salt of Safinamide, selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A. Phase 3.

S2102

Rasagiline Mesylate

Rasagiline Mesylate is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease.

S4246

Tranylcypromine (2-PCPA) HCl

Tranylcypromine is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively.

S3212

Moclobemide (Ro 111163)

Moclobemide is a MAO-A (5-HT) inhibitor with IC50 of 6.1 μM.

S4033

Sennoside A

Sennoside A, a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.

S4717New

Isatin

Isatin is an endogenous MAO inhibitor.

S2339

Paeonol

Paeonol (Peonol), a phenolic compound extracted from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum, inhibits MAO with an IC50 of about 50 μM.

Catalog No. Information Product Use Citations Product Validations
S1472

Safinamide Mesylate

Safinamide Mesylate is mesylate salt of Safinamide, selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A. Phase 3.

S2102

Rasagiline Mesylate

Rasagiline Mesylate is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease.

S4246

Tranylcypromine (2-PCPA) HCl

Tranylcypromine is a monoamine oxidase inhibitor, which inhibits CYP2A6 with Ki of 0.08 μM and 0.2 μM in cDNA-expressing microsomes and Human Liver Microsomes, respectively.

S3212

Moclobemide (Ro 111163)

Moclobemide is a MAO-A (5-HT) inhibitor with IC50 of 6.1 μM.

S4033

Sennoside A

Sennoside A, a kind of irritant laxative isolated from rhei rhizome, causes purgative actions in the intestine.

S4717New

Isatin

Isatin is an endogenous MAO inhibitor.

S2339

Paeonol

Paeonol (Peonol), a phenolic compound extracted from Chinese herbs Paeonia suffruticosa (moutan cortex) and Cynanchum paniculatum, inhibits MAO with an IC50 of about 50 μM.