Safinamide Mesylate (FCE28073) Chemical Structure
NXY-059 (Cerovive) is the disulfonyl derivative of the neuroprotective spin trap phenylbutynitrone or "PBN".
PTC124 also known as Ataluren is CFTR-G542X nonsense allele inhibitor.
Targeting VHL-deficient RCC cells, in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 μM).
BTZ043 racemate is a decaprenylphosphoryl-b-D-ribose 2’-epimerase inhibitor with MIC of 2.3 and 9.2 nM for M. tuberculosis H37Rv and Mycobacterium smegmatis, respectively.
cathepsin K inhibitor with an IC50 of 0.2nM.
A potent, orally active growth hormone (GH) secretagogue.
[Ala92]-p16 (84-103) is a CDK inhibitor with IC50 of 1.5μM for cyclin-dependent kinase-4 (cdk4)/cyclin D1
Bax inhibitor peptide,negative control is a negative control peptide for the Bax inhibitor peptides V5 and P5.
JNK and p38 MAPK inhibitor
SRC kinase inhibitor
Safinamide Mesylate (FCE28073) is a candidate compound against Parkinson’s disease with multiple methods of action. Safinamide Mesylate(FCE28073) is a monoamine oxidase B inhibitor, reducing degradation of dopamine. Safinamide Mesylate (FCE28073) is also a glutamate release inhibitor. Safinamide Mesylate (FCE28073) seems to inhibit dopamine reuptake. Furthermore, Safinamide Mesylate (FCE28073) blocks sodium and calcium channels. [1]
| Molecular Weight (WM): | 398.45 |
|---|---|
| Formula: | C17H19FN2O2.CH4O3S |
| CAS No.: | 202825-46-5 |
| Synonyms: |
FCE-28073(R-isomer), PNU-151774E, NW-1015
|
| Dissolve in (25°C): | DMSO ≥80mg/mL |
| Water ≥80mg/mL | |
| Ethanol ≥13mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
A collection of 864 bioactive compounds
A collection of 481 inhibitors
A collection of 194 kinase inhibitors
A collection of 85 tyrosine kinase inhibitors.
A collection of 426 FDA approved drugs
A collection of 139 natural products
A collection of 40 chemotherapeutic agents
A unique collection of 17 small molecule modulators
A unique collection of 47 small molecule inhibitors
A unique collection of 63 GPCR small molecules
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