CaSR

CaSR Products

  • All (3)
  • CaSR Activators (2)
  • CaSR Antagonist (1)
  • New CaSR Products
Catalog No. Product Name Information Product Use Citations Product Validations
S2633 NPS-2143 NPS-2143 (SB262470) is a novel potent and selective antagonist of Ca(2+) receptor with IC50 of 43 nM.
Biomed Pharmacother, 2023, 163:114843
Toxins (Basel), 2023, 16(1)21
Kaohsiung J Med Sci, 2022, 10.1002/kjm2.12601
S1260 Cinacalcet (AMG-073) HCl Cinacalcet (Mimpara, Sensipar,AMG-073) HCl represents a new class of compounds for the treatment of hyperparathyroidism.
Int J Mol Sci, 2022, 23(8)4323
Int J Mol Sci, 2020, 21(20)E7617
Mol Cell Endocrinol, 2020, 501:110654
E0359 Evocalcet Evocalcet (KHK7580) is an novel oral calcimimetic agent which acts via allosteric activation of the calcium sensing receptor (CaSR). Evocalcet (0, 20 and 60 nM) dose-dependently increases cytoplasmic [Ca2+] concentrations with an EC50 value of 92.7 nM in hCaR-HEK293 cells.
S1260 Cinacalcet (AMG-073) HCl Cinacalcet (Mimpara, Sensipar,AMG-073) HCl represents a new class of compounds for the treatment of hyperparathyroidism.
Int J Mol Sci, 2022, 23(8)4323
Int J Mol Sci, 2020, 21(20)E7617
Mol Cell Endocrinol, 2020, 501:110654
E0359 Evocalcet Evocalcet (KHK7580) is an novel oral calcimimetic agent which acts via allosteric activation of the calcium sensing receptor (CaSR). Evocalcet (0, 20 and 60 nM) dose-dependently increases cytoplasmic [Ca2+] concentrations with an EC50 value of 92.7 nM in hCaR-HEK293 cells.
S2633 NPS-2143 NPS-2143 (SB262470) is a novel potent and selective antagonist of Ca(2+) receptor with IC50 of 43 nM.
Biomed Pharmacother, 2023, 163:114843
Toxins (Basel), 2023, 16(1)21
Kaohsiung J Med Sci, 2022, 10.1002/kjm2.12601

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CaSRSignaling Pathway

CaSR信号通路图
Tags: CaSR inhibitor|CaSR agonist|CaSR activator|CaSR inducer|CaSR antagonist|CaSR signaling pathway|CaSR assay kit