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AMG-073 HCl (Cinacalcet HCl)

AMG-073 HCl (Cinacalcet hydrochloride) represents a new class of compounds for the treatment of hyperparathyroidism.

Catalog No.S1260

: Tel: +1-832-582-8158[email protected]

AMG-073 HCl (Cinacalcet HCl) Chemical Structure
Molecular Weight: 393.87

Validation & Quality Control

Quality Control & MSDS

Related Compound Libraries

AMG-073 HCl (Cinacalcet HCl) is available in the following compound libraries:

Chemical Library (96-well) FDA Approved Drug Library (96-well)

Product Information

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Dr. Antonino Maria Sparta demonstrates a breakthrough in leukemia research by utilizing two inhibitors produced by Selleck Chemicals.

Cat.No.	Product Name	Solubility (25°C)
S1260	AMG-073 HCl (Cinacalcet HCl)	1 mg/mL	79 mg/mL	33 mg/mL
S2633	NPS-2143 (SB262470)	<1 mg/mL	82 mg/mL	<1 mg/mL

Product Description

Biological Activity Chemical Information Tech Support & FAQs

Biological Activity

AMG-073 HCl (Cinacalcet hydrochloride) represents a new class of compounds for the treatment of hyperparathyroidism known as calcimimetics, which reduce parathyroid hormone (PTH) synthesis and secretion by increasing the sensitivity of the parathyroid calcium-sensing receptor (CaR) to extracellular calcium. The current study evaluates the efficacy and safety of AMG 073 when added to conventional treatment of secondary hyperparathyroidism in end-stage renal disease (ESRD).^[1]

Chemical Information

Download AMG-073 HCl (Cinacalcet HCl) SDF

Molecular Weight (MW)	393.87
Formula	C₂₂H₂₂F₃N.HCl
CAS No.	364782-34-3, 226256-56-0 (free base), 1025064-29-2 (acetate)
Synonyms	Mimpara, Sensipar

Solubility (25°C) DMSO 79 mg/mL Water 1 mg/mL Ethanol 33 mg/mL
Storage	2 years -20°CPowder
	2 weeks4°Cin DMSO
	6 months-80°Cin DMSO

Chemical Name	(R)-N-(1-(naphthalen-1-yl)ethyl)-3-(3-(trifluoromethyl)phenyl)propan-1-amine hydrochloride

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Tech Support & FAQs

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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AMG-073 HCl (Cinacalcet HCl)