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(S)-Glutamic acid GluR agonist

Cat.No.S6266

(S)-Glutamic acid (L-Glutamic acid) is an endogenous, non-selective glutamate receptor agonist.
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Quality Control

Batch: S626601 Water]5 mg/mL]true]DMSO]Insoluble]false]]]false Purity: 98.72%
98.72

Solubility

In vitro
Batch:

Water : 5 mg/mL (超声加热十五分钟,60℃)

DMSO : Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

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In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 147.13 Formula

C5H9NO4

Storage (From the date of receipt) 3 years -20°C powder
CAS No. 56-86-0 -- Storage of Stock Solutions

Synonyms L-Glutamic acid SMILES C(CC(=O)O)C(C(=O)O)N

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Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-09-01)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05894343 ACTIVE_NOT_RECRUITING
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MeiraGTx, LLC
2023-05-19 PHASE1; PHASE2
NCT05018585 TERMINATED
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Diamyd Medical AB
2022-05-19 PHASE3
NCT05339529 RECRUITING
Acute Aortic Syndrome; Aortic Dissection Type a
Nanjing Medical University
2022-07-01
NCT05603312 COMPLETED
Parkinson's Disease
MeiraGTx, LLC
2022-10-05 PHASE1; PHASE2
NCT05221892 COMPLETED
Vertigo
Fundação Educacional Serra dos Órgãos
2021-11-22 PHASE4
NCT04262479 COMPLETED
Latent Autoimmune Diabetes in Adults
Norwegian University of Science and Technology
2020-03-02 PHASE2

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