Capric acid

Catalog No.S6906 Synonyms: DA, Decanoic acid, Decylic acid

For research use only.

Capric acid (DA, Decanoic acid, Decylic acid), a component of medium-chain triclycerides occurring naturally in coconut oil and palm kernel oil, contributes to seizure control through direct AMPA receptor inhibition. Capric acid is also a modulating ligand for PPARs. Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

Capric acid Chemical Structure

CAS No. 334-48-5

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Biological Activity

Description Capric acid (DA, Decanoic acid, Decylic acid), a component of medium-chain triclycerides occurring naturally in coconut oil and palm kernel oil, contributes to seizure control through direct AMPA receptor inhibition. Capric acid is also a modulating ligand for PPARs. Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.
Targets
AMPA receptor [1]
()
PPAR [2]
()

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 34 mg/mL
(197.37 mM)
Water 34 mg/mL
(197.37 mM)
Ethanol 34 mg/mL
(197.37 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 172.26
Formula

C10H20O2

CAS No. 334-48-5
Storage 3 years -20°C powder
2 years -80°C in solvent

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04005534 Suspended Drug: Regular group|Drug: Preemptive group Postoperative Pain|Rotator Cuff Injuries University of Sao Paulo General Hospital November 10 2023 Not Applicable
NCT04304079 Not yet recruiting Device: ARssist system Prostate Cancer Chinese University of Hong Kong March 1 2022 Not Applicable
NCT05169385 Not yet recruiting Behavioral: Parent SMART|Behavioral: Treatment as Usual Substance Use|Adolescent Behavior Brown University|National Institute on Drug Abuse (NIDA) February 1 2022 Not Applicable

(data from https://clinicaltrials.gov, updated on 2022-01-17)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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