Sulfabenzamide

Catalog No.S4576 Synonyms: Sultrin, N-Sulfanilylbenzamide

For research use only.

Sulfabenzamide (Sultrin, N-Sulfanilylbenzamide) is an antibacterial/antimicrobial which also exhibit their antitumor effects through multiple mechanisms including inhibition of membrane bound carbonic anhydrases, prevention of microtubule assembly, cell cycle arrest, and inhibition of angiogenesis.

Sulfabenzamide Chemical Structure

CAS No. 127-71-9

Purity & Quality Control

Choose Selective Bacterial Inhibitors

Biological Activity

Description Sulfabenzamide (Sultrin, N-Sulfanilylbenzamide) is an antibacterial/antimicrobial which also exhibit their antitumor effects through multiple mechanisms including inhibition of membrane bound carbonic anhydrases, prevention of microtubule assembly, cell cycle arrest, and inhibition of angiogenesis.
In vitro

Sulfabenzamide inhibits the proliferation and increases Caspase-3 activity in T-47D cells. It dose not induce apoptosis but a minimal shift from G1 to S and G2/M phases of the cell cycle[1].

Protocol (from reference)

Cell Research:[1]
  • Cell lines: T-47D breast cancer cells
  • Concentrations: 0-20 mM
  • Incubation Time: 24, 48 and 72 h
  • Method: The MTT assay is used to evaluate the viability of T-47D cells incubated with different concentrations of sulfabenzamide (0.0-20 mM) or doxorubicin (0.0-0.6 μM) after 24, 48 and 72 h.

Solubility (25°C)

In vitro

DMSO 55 mg/mL
(199.05 mM)
Water Insoluble
Ethanol Insoluble

Chemical Information

Molecular Weight 276.31
Formula

C13H12N2O3S

CAS No. 127-71-9
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C1=CC=C(C=C1)C(=O)NS(=O)(=O)C2=CC=C(C=C2)N

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Sulfabenzamide | Sulfabenzamide ic50 | Sulfabenzamide price | Sulfabenzamide cost | Sulfabenzamide solubility dmso | Sulfabenzamide purchase | Sulfabenzamide manufacturer | Sulfabenzamide research buy | Sulfabenzamide order | Sulfabenzamide mouse | Sulfabenzamide chemical structure | Sulfabenzamide mw | Sulfabenzamide molecular weight | Sulfabenzamide datasheet | Sulfabenzamide supplier | Sulfabenzamide in vitro | Sulfabenzamide cell line | Sulfabenzamide concentration | Sulfabenzamide nmr