Succinylcholine Chloride Dihydrate

Synonyms: Suxamethonium Chloride Dihydrate

Succinylcholine Chloride Dihydrate (Suxamethonium) is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.

Succinylcholine Chloride Dihydrate Chemical Structure

Succinylcholine Chloride Dihydrate Chemical Structure

CAS No. 6101-15-1

Purity & Quality Control

Succinylcholine Chloride Dihydrate Related Products

Signaling Pathway

Biological Activity

Description Succinylcholine Chloride Dihydrate (Suxamethonium) is a nicotinic AChR agonist and also acts as a depolarizing neuromuscular blocker.
Targets
nAChR [1]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03415607 Unknown status
Suxamethonium Sensitivity|Aspiration of Gastric Contents Into Respiratory Tract Part Unspecified
University Hospital Caen
November 6 2017 --
NCT02925143 Completed
Neuromuscular Blockade
Herlev Hospital|Merck Sharp & Dohme LLC
November 21 2016 Not Applicable

Chemical Information & Solubility

Molecular Weight 397.34 Formula

C14H30N2O4.2Cl.2H2O

CAS No. 6101-15-1 SDF Download Succinylcholine Chloride Dihydrate SDF
Smiles C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C.O.O.[Cl-].[Cl-]
Storage (From the date of receipt)

In vitro
Batch:

Water : 79 mg/mL

DMSO : 21 mg/mL ( (52.85 mM) Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


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In vivo
Batch:

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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