CAS No. 6101-15-1

Batch: Purity:99.50
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Succinylcholine Chloride Dihydrate Chemical Structure
Chemical Structure
Check the Succinylcholine Chloride Dihydrate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 6101-15-1
Molecular Formula

C14H30N2O4.2Cl.2H2O
Molecular Weight (MW) 397.34
SMILES C[N+](C)(C)CCOC(=O)CCC(=O)OCC[N+](C)(C)C.O.O.[Cl-].[Cl-]

Ordering Information

Biological Activity

Succinylcholine Chloride Dihydrate (Suxamethonium) is a nicotinic acetylcholine receptor (nAChR) agonist and depolarizing neuromuscular blocker. It binds to nicotinic AChRs at the neuromuscular junction to induce sustained membrane depolarization at the motor endplate. This prolonged depolarizing action prevents subsequent endplate activation by endogenous acetylcholine, leading to the inhibition of neuromuscular transmission and cellular desensitization.

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 79 mg/mL
DMSO 21 mg/mL (52.85 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.