Scopolamine HBr trihydrate

Catalog No.S5873

Scopolamine HBr trihydrate Chemical Structure

Molecular Weight(MW): 438.31

Scopolamine HBr is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 55.3 nM.

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Biological Activity

Description Scopolamine HBr is a competitive muscarinic acetylcholine receptor antagonist with an IC50 of 55.3 nM.
Targets
mAChR [1]
()

Protocol

Solubility (25°C)

In vitro DMSO 88 mg/mL (200.77 mM)
Water 88 mg/mL (200.77 mM)
Ethanol 4 mg/mL (9.12 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 438.31
Formula

C17H28BrNO7

CAS No. 6533-68-2
Storage powder
in solvent
Synonyms N/A

Bio Calculators

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Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03874130 Recruiting Drug: Scopolamine Major Depressive Disorder (MDD) Repurposed Therapeutics Inc. August 1 2018 Phase 1
NCT03131050 Completed Drug: Scopolamine|Drug: Escitalopram|Drug: Saline Major Depressive Disorder Capital Medical University March 15 2017 Phase 4

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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AChR Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID