CAS No. 6533-68-2

Batch: Purity:99.29
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Scopolamine HBr trihydrate Chemical Structure
Chemical Structure
Check the Scopolamine HBr trihydrate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 6533-68-2
Molecular Formula

C17H28BrNO7
Molecular Weight (MW) 438.31
SMILES CN1C2CC(CC1C3C2O3)OC(=O)C(CO)C4=CC=CC=C4.O.O.O.Br

Ordering Information

Biological Activity

Scopolamine HBr trihydrate is a competitive muscarinic acetylcholine receptor antagonist. By competitively blocking muscarinic receptors, it interrupts central cholinergic neurotransmission and modulates downstream signaling pathways essential for cognitive function. This target inhibition attenuates intracellular signaling cascades and synaptic plasticity, leading to transient impairments in learning, spatial memory, and executive function in cellular and animal models. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
1 mg 5 mg 10 mg
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 88 mg/mL (200.77 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 88 mg/mL
Ethanol 15 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.