Pentoxyverine Citrate

Catalog No.S4143 Synonyms: Carbetapentane Citrate

For research use only.

Pentoxyverine Citrate (Carbetapentane) is an antitussive (cough suppressant) commonly used for cough associated with illnesses like common cold.

Pentoxyverine Citrate Chemical Structure

CAS No. 23142-01-0

Purity & Quality Control

Choose Selective AChR Inhibitors

Other AChR Products

Biological Activity

Description Pentoxyverine Citrate (Carbetapentane) is an antitussive (cough suppressant) commonly used for cough associated with illnesses like common cold.
Targets
mAChR [2]
In vitro

Pentoxyverine (Carbetapentane) Citrate has atropine-like and local anaesthetic actions and effectively suppresses acute cough due to common upper respiratory infections. [1] Pentoxyverine suppresses the cough reflex in the central nervous system, but the exact mechanism of action is not known with certainty. The drug acts as an antagonist at muscarinic receptors (subtype M1) and as an agonist at sigma receptors (subtype σ1). Its anticholinergic properties can theoretically relax the pulmonary alveoli and reduce phlegm production. [2]

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 100 mg/mL
(190.26 mM)
Water 100 mg/mL
(190.26 mM)
Ethanol 8 mg/mL
(15.22 mM)

Chemical Information

Molecular Weight 525.59
Formula

C20H31NO3.C6H8O7

CAS No. 23142-01-0
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CCN(CC)CCOCCOC(=O)C1(CCCC1)C2=CC=CC=C2.C(C(=O)O)C(CC(=O)O)(C(=O)O)O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

Tel: +1-832-582-8158 Ext:3
If you have any other enquiries, please leave a message.

* Indicates a Required Field

Please enter your name.
Please enter your email. Please enter a valid email address.
Please write something to us.
Tags: buy Pentoxyverine Citrate | Pentoxyverine Citrate ic50 | Pentoxyverine Citrate price | Pentoxyverine Citrate cost | Pentoxyverine Citrate solubility dmso | Pentoxyverine Citrate purchase | Pentoxyverine Citrate manufacturer | Pentoxyverine Citrate research buy | Pentoxyverine Citrate order | Pentoxyverine Citrate mouse | Pentoxyverine Citrate chemical structure | Pentoxyverine Citrate mw | Pentoxyverine Citrate molecular weight | Pentoxyverine Citrate datasheet | Pentoxyverine Citrate supplier | Pentoxyverine Citrate in vitro | Pentoxyverine Citrate cell line | Pentoxyverine Citrate concentration | Pentoxyverine Citrate nmr