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Pancreatin Lipase chemical

Cat.No.S4825

Pancreatin (Pancrelipase, Pancreatic enzymes), are commercial mixtures of amylase, lipase, and protease. They are used to treat malabsorption syndrome due to pancreatic problems.(PROTEASE ACTIVITY ≥ 275 USP.u/mg;Amvlase activity ≥ 275 USP.u/mg;Lipase Activity ≥ 22 USP.u/mg)
Pancreatin Lipase chemical Chemical Structure

Chemical Structure

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Quality Control

Batch: S482501 4-Methylpyridine]7 mg/mL]true]DMSO]0.01 mg/mL]false]Water]Insoluble]false Purity: 98%
98

Solubility

In vitro
Batch:

4-Methylpyridine : 7 mg/mL

DMSO : 0.01 mg/mL
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : Insoluble

Molarity Calculator

Mass Concentration Volume Molecular Weight
Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg
g
μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO
%
% Tween 80
% ddH2O
% DMSO
+
%

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight Formula Storage (From the date of receipt)
CAS No. 8049-47-6 -- Storage of Stock Solutions

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06023771 Recruiting
Acute Pancreatitis
Peking Union Medical College Hospital
October 2023 --
NCT05450627 Recruiting
Exocrine Pancreatic Insufficiency
Hospital Clinico Universitario de Santiago
June 1 2021 --
NCT05132309 Completed
Chronic Pancreatitis|Pancreatic Exocrine Insufficiency
Federal Research and Clinical Center of Physical-Chemical Medicine|Moscow State University of Medicine and Dentistry
November 1 2020 --
NCT04195347 Recruiting
Acute Pancreatitis
St. Jude Children''s Research Hospital|CalciMedica Inc.
September 4 2020 Phase 1|Phase 2
NCT04917172 Completed
Acute Pancreatitis|Pancreatic Fistula|Postoperative Complications
Azienda Ospedaliera Universitaria Integrata Verona
April 10 2019 --

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