Lipase

Inhibitory Selectivity

Lipase Products

New Lipase Products
Catalog No. Information Product Use Citations Product Validations
S1629

Orlistat

Orlistat is a general lipase inhibitor with IC50 of 122 ng/ml for PL from human duodenal juice.

S4904

JZL184

JZL 184 is the first selective inhibitor of monoacylglycerol lipase (MAGL) with IC50 of 8 nM.

S7364

Atglistatin

Atglistatin is a highly potent, and selective inhibitor of adipose triglyceride lipase (ATGL) with IC50 of 0.7 μM, high selectivity over other key metabolic lipases.

S7457

XEN445

XEN445 is a potent and selective endothelial lipase inhibitor with IC50 of 0.237 μM.

S9234New

Schaftoside

Schaftoside, a bioactive compound found in the Herba Desmodii Styracifolii, exhibits pancreatic lipase inhibitory activity.

S6609New

JZL195

JZL195 is a potent inhibitor of both FAAH and MAGL with IC50s of 2 and 4 nM respectively.

S8823New

ABX-1431

ABX-1431 is a highly potent, selective, and CNS-penetrant Monoacylglycerol lipase (MGLL) inhibitor with IC50 values of 14 nM and 27 nM for hMGLL and mMGLL respectively.

S2365

Tanshinone IIA

Tanshinone IIA(Tanshinone B) is the most abundant diterpene quinone in Danshen, Salviae miltiorrhizae Radix, a widely prescribed traditional herbal medicine that is used to treat cardiovascular and inflammatory diseases; A natural monoacylglycerol lipase inhibitor.

S4930

Cetilistat

Cetilistat is a novel highly lipophilic benzoxazinone that inhibits gastrointestinal and pancreatic lipases. It shows a good safety and tolerability profile in vivo

S4825

Pancreatin

Pancreatic enzymes also known as pancrelipase and pancreatin, are commercial mixtures of amylase, lipase, and protease. They are used to treat malabsorption syndrome due to pancreatic problems.

Catalog No. Information Product Use Citations Product Validations
S1629

Orlistat

Orlistat is a general lipase inhibitor with IC50 of 122 ng/ml for PL from human duodenal juice.

S4904

JZL184

JZL 184 is the first selective inhibitor of monoacylglycerol lipase (MAGL) with IC50 of 8 nM.

S7364

Atglistatin

Atglistatin is a highly potent, and selective inhibitor of adipose triglyceride lipase (ATGL) with IC50 of 0.7 μM, high selectivity over other key metabolic lipases.

S7457

XEN445

XEN445 is a potent and selective endothelial lipase inhibitor with IC50 of 0.237 μM.

S9234New

Schaftoside

Schaftoside, a bioactive compound found in the Herba Desmodii Styracifolii, exhibits pancreatic lipase inhibitory activity.

S6609New

JZL195

JZL195 is a potent inhibitor of both FAAH and MAGL with IC50s of 2 and 4 nM respectively.

S8823New

ABX-1431

ABX-1431 is a highly potent, selective, and CNS-penetrant Monoacylglycerol lipase (MGLL) inhibitor with IC50 values of 14 nM and 27 nM for hMGLL and mMGLL respectively.

S2365

Tanshinone IIA

Tanshinone IIA(Tanshinone B) is the most abundant diterpene quinone in Danshen, Salviae miltiorrhizae Radix, a widely prescribed traditional herbal medicine that is used to treat cardiovascular and inflammatory diseases; A natural monoacylglycerol lipase inhibitor.

S4930

Cetilistat

Cetilistat is a novel highly lipophilic benzoxazinone that inhibits gastrointestinal and pancreatic lipases. It shows a good safety and tolerability profile in vivo

Catalog No. Information Product Use Citations Product Validations
S4825

Pancreatin

Pancreatic enzymes also known as pancrelipase and pancreatin, are commercial mixtures of amylase, lipase, and protease. They are used to treat malabsorption syndrome due to pancreatic problems.