Lipase
- Inhibitory Selectivity
- Solubility
| Catalog No. | Product Name | Solubility(25°C) | ||
|---|---|---|---|---|
| Water | DMSO | Alcohol | ||
| S1629 | Orlistat | <1 mg/mL | 99 mg/mL | 99 mg/mL |
| S4904 | JZL184 | <1 mg/mL | 100 mg/mL | <1 mg/mL |
| S7364 | Atglistatin | <1 mg/mL | 56 mg/mL | 4 mg/mL |
| S7457 | XEN445 | <1 mg/mL | 80 mg/mL | 34 mg/mL |
| S9234 | Schaftoside | -1 mg/mL | 100 mg/mL | -1 mg/mL |
| S2365 | Tanshinone IIA | <1 mg/mL | 5 mg/mL | <1 mg/mL |
| S4930 | Cetilistat | <1 mg/mL | 3 mg/mL | 8 mg/mL |
| S4825 | Pancreatin | <1 mg/mL | 0.01 mg/mL | <1 mg/mL |
Lipase Products
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S1629 |
OrlistatOrlistat is a general lipase inhibitor with IC50 of 122 ng/ml for PL from human duodenal juice. |
||
| S4904 |
JZL184JZL 184 is the first selective inhibitor of monoacylglycerol lipase (MAGL) with IC50 of 8 nM. |
||
| S7364 |
AtglistatinAtglistatin is a highly potent, and selective inhibitor of adipose triglyceride lipase (ATGL) with IC50 of 0.7 μM, high selectivity over other key metabolic lipases. |
C, G0s2-null MEFs were transfected with HRAS and the following day treated with either 40 mmol/L of ATGL inhibitor atglistatin or DMSO (Vehicle) every 2 days. Left, representative plates. Right, the average of biologic triplicate determinations. Error bars, SD. The experiment was repeated twice with similar results.
|
|
| S7457 |
XEN445XEN445 is a potent and selective endothelial lipase inhibitor with IC50 of 0.237 μM. |
||
| S9234New |
SchaftosideSchaftoside, a bioactive compound found in the Herba Desmodii Styracifolii, exhibits pancreatic lipase inhibitory activity. |
||
| S2365 |
Tanshinone IIATanshinone IIA(Tanshinone B) is the most abundant diterpene quinone in Danshen, Salviae miltiorrhizae Radix, a widely prescribed traditional herbal medicine that is used to treat cardiovascular and inflammatory diseases; A natural monoacylglycerol lipase inhibitor. |
Western blotting analysis of b-catenin, TCF3 and LEF1 levels in HT-29 cells. b-actin is the loading control.
|
|
| S4930 |
CetilistatCetilistat is a novel highly lipophilic benzoxazinone that inhibits gastrointestinal and pancreatic lipases. It shows a good safety and tolerability profile in vivo |
||
| S4825New |
PancreatinPancreatic enzymes also known as pancrelipase and pancreatin, are commercial mixtures of amylase, lipase, and protease. They are used to treat malabsorption syndrome due to pancreatic problems. |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S1629 |
OrlistatOrlistat is a general lipase inhibitor with IC50 of 122 ng/ml for PL from human duodenal juice. |
||
| S4904 |
JZL184JZL 184 is the first selective inhibitor of monoacylglycerol lipase (MAGL) with IC50 of 8 nM. |
||
| S7364 |
AtglistatinAtglistatin is a highly potent, and selective inhibitor of adipose triglyceride lipase (ATGL) with IC50 of 0.7 μM, high selectivity over other key metabolic lipases. |
C, G0s2-null MEFs were transfected with HRAS and the following day treated with either 40 mmol/L of ATGL inhibitor atglistatin or DMSO (Vehicle) every 2 days. Left, representative plates. Right, the average of biologic triplicate determinations. Error bars, SD. The experiment was repeated twice with similar results.
|
|
| S7457 |
XEN445XEN445 is a potent and selective endothelial lipase inhibitor with IC50 of 0.237 μM. |
||
| S9234New |
SchaftosideSchaftoside, a bioactive compound found in the Herba Desmodii Styracifolii, exhibits pancreatic lipase inhibitory activity. |
||
| S2365 |
Tanshinone IIATanshinone IIA(Tanshinone B) is the most abundant diterpene quinone in Danshen, Salviae miltiorrhizae Radix, a widely prescribed traditional herbal medicine that is used to treat cardiovascular and inflammatory diseases; A natural monoacylglycerol lipase inhibitor. |
Western blotting analysis of b-catenin, TCF3 and LEF1 levels in HT-29 cells. b-actin is the loading control.
|
|
| S4930 |
CetilistatCetilistat is a novel highly lipophilic benzoxazinone that inhibits gastrointestinal and pancreatic lipases. It shows a good safety and tolerability profile in vivo |
| Catalog No. | Information | Product Use Citations | Product Validations |
|---|---|---|---|
| S4825New |
PancreatinPancreatic enzymes also known as pancrelipase and pancreatin, are commercial mixtures of amylase, lipase, and protease. They are used to treat malabsorption syndrome due to pancreatic problems. |
