Palmitoleic acid | AMPK activator | Highly Cited | In Stock

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Quality Control

Batch: Purity: 99.83%

99.83

Related Targets	PI3K Akt mTOR GSK-3 ATM/ATR DNA-PK PDPK1 PTEN PI4K PP2A
Other AMPK Inhibitors	Dorsomorphin Dihydrochloride Dorsomorphin (Compound C) AICAR (Acadesine) A-769662 GSK621 WZ4003 Ex229 (Compound 991) Phenformin HCl BAY-3827 HTH-01-015

Solubility

In vitro
Batch:

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.
Clear solution	5%DMSO 1 40%PEG300 2 5%Tween80 3 50%ddH2O Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	2.550mg/ml (10.02mM)	Taking the 1 mL working solution as an example, add 50 μL of 51 mg/ml clarified DMSO stock solution to 400 μL of PEG300, mix evenly to clarify it; add 50 μL of Tween80 to the above system, mix evenly to clarify; then continue to add 500 μL of ddH2O to adjust the volume to 1 mL. The mixed solution should be used immediately for optimal results.
Clear solution	5% DMSO 1 95% Corn oil Validated by Selleck labs. Should you need adjustments to this formulation, contact our sales team for custom testing.	2.550mg/ml (10.02mM)	Taking the 1 mL working solution as an example, add 50 μL of 51 mg/ml clear DMSO stock solution to 950 μL of corn oil and mix evenly. The mixed solution should be used immediately for optimal results.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

%

% Tween 80

% ddH₂O

% DMSO

+

%

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	254.41	Formula	C₁₆H₃₀O₂	Storage (From the date of receipt)	2 years 4°C liquid
CAS No.	373-49-9	--		Storage (From the date of receipt)	2 years 4°C liquid
Synonyms	POA, Palmitoleate			SMILES	CCCCCC\C=C/CCCCCCCC(O)=O

Read more about storage stability stock solution CAS number SMILES

Mechanism of Action

Targets/IC₅₀/Ki	AMPK FGF-21
References	[1] https://pubmed.ncbi.nlm.nih.gov/27925195/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2026-02-18)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT07417696	NOT_YET_RECRUITING	Crohn's Disease	Chinese Medical Association	2026-04-01	PHASE4
NCT03372733	RECRUITING	Cardiovascular Disease	National Heart, Lung, and Blood Institute (NHLBI)	2018-07-31	PHASE2
NCT05560971	ACTIVE_NOT_RECRUITING	PreDiabetes; Insulin Resistance; Overweight; Obesity	Brigham and Women's Hospital	2022-11-01
NCT06928701	RECRUITING	Early Breast Cancer; Neoadjuvant Treatment	University of Eastern Piedmont	2024-09-01
NCT07547254	ENROLLING_BY_INVITATION	Pressure Ulcer Prevention	Ruijin Hospital	2025-12-01
NCT05556967	Completed	Adherence Patient	University of Mississippi Medical Center\|University of Mississippi National Center for Natural Products Research\|National Center for Complementary and Integrative Health (NCCIH)	2023-08-09	Not Applicable

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Palmitoleic acid AMPK activator

Chemical Structure

Molecular Weight: 254.41