CAS No. 548-04-9
Batch:
Purity:98.36
Chemical Structure
Check the
Hypericin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 9,11,13,16,18,20-hexahydroxy-5,24-dimethyloctacyclo[13.11.1.12,10.03,8.04,25.019,27.021,26.014,28]octacosa-1(26),2,4(25),5,8,10,12,14(28),15(27),16,18,20,23-tridecaene-7,22-dione | |
|---|---|---|
| CAS Number | 548-04-9 | |
| Molecular Formula |
C30H16O8 |
|
| Molecular Weight (MW) | 504.44 | |
| InChIKey | YDOIFHVUBCIUHF-UHFFFAOYSA-N |
Hypericin is a naturally occurring anthraquinone derivative that acts as an inhibitor of protein kinase C (PKC) and monoamine oxidase (MAO). Inhibition of PKC signaling disrupts kinase-mediated intracellular pathways, leading to antiproliferative effects and apoptosis in cancer cells. Furthermore, hypericin exhibits potent light-dependent virucidal activity against enveloped viruses, inhibiting viral replication and host cell infection. [1][2]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(198.23 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(198.23 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.