Goitrin

For research use only.

Catalog No.S3251 Synonyms: DL-Goitrin, (R, S)-Goitrin, R,S-goitrin

Goitrin Chemical Structure

CAS No. 13190-34-6

Goitrin (DL-Goitrin, (R, S)-Goitrin, R,S-goitrin) is one of the main constituent of Radix isatidis (Banlangen) which is widely used as a traditional Chinese medicine for treating fever and removing toxic heat. Goitrin exhibits antiviral and antiendotoxin activity.

Purity & Quality Control

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Biological Activity

Description Goitrin (DL-Goitrin, (R, S)-Goitrin, R,S-goitrin) is one of the main constituent of Radix isatidis (Banlangen) which is widely used as a traditional Chinese medicine for treating fever and removing toxic heat. Goitrin exhibits antiviral and antiendotoxin activity.

Protocol

Solubility (25°C)

In vitro DMSO 100 mg/mL (774.11 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 129.18
Formula

C5H7NOS

CAS No. 13190-34-6
Storage powder
in solvent
Synonyms DL-Goitrin, (R, S)-Goitrin, R,S-goitrin

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
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Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O
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Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
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    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

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Instructions to calculate molar mass (molecular weight) of a chemical compound:

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04998006 Not yet recruiting Drug: Alcohol and Cannabis vs. Alcohol only Cannabis Use|Alcohol Use|Inflammation Colorado State University|University of Colorado Boulder February 1 2022 --
NCT05020015 Not yet recruiting Biological: TAK-007|Drug: Chemotherapy Agents Relapsed or Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL) Takeda November 8 2021 Phase 2
NCT04968899 Not yet recruiting Drug: Neofordex®|Drug: Intravenous immunoglobulins Immune Thrombocytopenia (ITP) Assistance Publique - Hôpitaux de Paris October 1 2021 Phase 3
NCT04752683 Not yet recruiting Other: MyBuddy Employee Wellbeing App Work Related Stress Holly Risdon|BPAi|American Institute of Stress October 2021 --
NCT05028751 Not yet recruiting Drug: Lanraplenib|Drug: Gilteritinib Acute Myeloid Leukemia|Relapsed Acute Myeloid Leukemia|Refractory Acute Myeloid Leukemia Kronos Bio October 18 2021 Phase 1|Phase 2

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID