Goitrin

Catalog No.S3251 Synonyms: DL-Goitrin, (R, S)-Goitrin, R,S-goitrin

For research use only.

Goitrin (DL-Goitrin, (R, S)-Goitrin, R,S-goitrin) is one of the main constituent of Radix isatidis (Banlangen) which is widely used as a traditional Chinese medicine for treating fever and removing toxic heat. Goitrin exhibits antiviral and antiendotoxin activity.

Goitrin Chemical Structure

CAS No. 13190-34-6

Purity & Quality Control

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Biological Activity

Description Goitrin (DL-Goitrin, (R, S)-Goitrin, R,S-goitrin) is one of the main constituent of Radix isatidis (Banlangen) which is widely used as a traditional Chinese medicine for treating fever and removing toxic heat. Goitrin exhibits antiviral and antiendotoxin activity.

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 100 mg/mL
(774.11 mM)


Chemical Information

Molecular Weight 129.18
Formula

C5H7NOS

CAS No. 13190-34-6
Storage 3 years -20°C powder
2 years -80°C in solvent

In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04998006 Not yet recruiting Drug: Alcohol and Cannabis vs. Alcohol only Cannabis Use|Alcohol Use|Inflammation Colorado State University|University of Colorado Boulder February 1 2022 --
NCT04252625 Not yet recruiting Drug: Q-Urol|Drug: Placebo Prostate Adenocarcinoma University of Utah|Farr Labs LLC February 2022 Phase 2
NCT05140785 Not yet recruiting Diagnostic Test: Advanced MRI sequences Glioma Thomas Booth|Erasmus University Rotterdam The Netherlands|King''s College London|King''s College Hospital NHS Trust January 1 2022 Not Applicable
NCT04968899 Not yet recruiting Drug: Neofordex®|Drug: Intravenous immunoglobulins Immune Thrombocytopenia (ITP) Assistance Publique - Hôpitaux de Paris January 1 2022 Phase 3
NCT05177068 Not yet recruiting Drug: fruquintinib + sintilimab + SOX Gastric Cancer Henan Cancer Hospital January 2022 Phase 2
NCT03772717 Not yet recruiting Device: VitalStim 400|Device: VitalStim400 Chronic Inflammatory Demyelinating Polyneuropathy Emory University|Georgia Institute of Technology January 24 2022 Not Applicable

(data from https://clinicaltrials.gov, updated on 2022-01-17)

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