Home Proteases Tyrosinase inhibitor Glycolic acid For research use only.

Glycolic acid

Synonyms: dicarbonous acid, hydroxyacetic acid, hydroacetic acid

Glycolic acid (dicarbonous acid, hydroxyacetic acid, hydroacetic acid) is the smallest alpha-hydroxy acid. Due to its excellent capability to penetrate skin, glycolic acid is often used in skin care products, most often as a chemical peel. Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.

Glycolic acid Chemical Structure

Glycolic acid Chemical Structure

CAS: 79-14-1

Purity & Quality Control

Batch: S627201 DMSO] 15 mg/mL] false] Water] 10 mg/mL] false] ] ] false Purity: 98%
98

Glycolic acid Related Products

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Biological Activity

Description Glycolic acid (dicarbonous acid, hydroxyacetic acid, hydroacetic acid) is the smallest alpha-hydroxy acid. Due to its excellent capability to penetrate skin, glycolic acid is often used in skin care products, most often as a chemical peel. Glycolic acid is an inhibitor of tyrosinase, suppressing melanin formation and lead to a lightening of skin colour.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05362500 Completed
Melasma
Combined Military Hospital Abbottabad
 June 1 2021 Phase 1
NCT03437265 Completed
Pharmacokinetic
Norgine|Quotient Sciences
 September 3 2020 Phase 1
NCT01289171 Completed
Flat Warts|HIV
University of Pennsylvania|NeoStrata Company Inc.|Penn Center for AIDS Research (CFAR)
 January 2009 Not Applicable

Chemical Information & Solubility

Molecular Weight 76.05 Formula

C2H4O3
CAS No. 79-14-1 SDF --
Smiles C(C(=O)O)O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 15 mg/mL ( (197.23 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 10 mg/mL


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In vivo
Batch:

Add solvents to the product individually and in order.


In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO % % Tween 80 % ddH2O
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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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