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Gentamicin Antiviral chemical

Cat.No.S6289

Gentamicin, an aminoglycoside class of bactericidal antibiotic, is effective against gram-negative bacterial infections.This compound can be used to induce animal models of Renal Failure.
Gentamicin Antiviral chemical Chemical Structure

Chemical Structure

Molecular Weight: 1390.71

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability

Quality Control

Chemical Information, Storage & Stability

Molecular Weight 1390.71 Formula

C60H123N15O21

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 1403-66-3 -- Storage of Stock Solutions

Solubility

In vitro
Batch:

Water : 100 mg/mL

DMSO : Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : Insoluble

Molarity Calculator

Mass Concentration Volume Molecular Weight

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg
g
μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO
%
% Tween 80
% ddH2O
% DMSO
+
%

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

References

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06387147 Not yet recruiting
Acute Mesenteric Ischemia
Assistance Publique - Hôpitaux de Paris
 September 1 2024 Phase 3
NCT06362447 Not yet recruiting
Ichthyosis
University Hospital Toulouse
 April 23 2024 Phase 2
NCT05593601 Recruiting
Colonization Asymptomatic
Mahidol University
 November 24 2022 Phase 4
NCT05503147 Recruiting
Malnutrition|Anorexia|Cannabis|Aging|Emergency Service Hospital|Renal Function|Pharmacokinetics
Ove Andersen|University Hospital Bispebjerg and Frederiksberg|North Denmark Regional Hospital|University of Copenhagen|Region Hovedstadens Apotek|Glostrup University Hospital Copenhagen|Hvidovre University Hospital
 March 24 2022 Phase 1
NCT05251584 Unknown status
Peritoneal Dialysis-related Infection
Phramongkutklao College of Medicine and Hospital|Silpakorn University
 December 1 2021 Not Applicable

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