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AR-C155858 MCT inhibitor

Cat.No.S7919

AR-C155858 is a selective monocarboxylate transporter MCT1 and MCT2 inhibitor with Ki value of 2.3 nM and 10 nM, respectively.
AR-C155858 MCT inhibitor Chemical Structure

Chemical Structure

Molecular Weight: 461.54

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Quality Control

Batch: S791901 DMSO]92 mg/mL]false]Ethanol]92 mg/mL]false]Water]8 mg/mL]false Purity: 99.68%
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  • COA
  • NMR
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99.68

Solubility

In vitro
Batch:

DMSO : 92 mg/mL (199.33 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Ethanol : 92 mg/mL

Water : 8 mg/mL

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Mass Concentration Volume Molecular Weight
Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg
g
μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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%
% Tween 80
% ddH2O
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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 461.54 Formula

C21H27N5O5S

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 496791-37-8 -- Storage of Stock Solutions

Synonyms N/A Smiles CC1=C(C(=NN1)C)CC2=C(C3=C(S2)N(C(=O)N(C3=O)C)CC(C)C)C(=O)N4CC(CO4)O

Mechanism of Action

Targets/IC50/Ki
MCT1
2.3 nM(Ki)
MCT2
10 nM(Ki)
References

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