Moxifloxacin

Catalog No.S5535 Synonyms: BAY12-8039

For research use only.

Moxifloxacin is an antibiotic used to treat a number of bacterial infections, active against Mycobacterium tuberculosis in vitro.

Moxifloxacin Chemical Structure

CAS No. 151096-09-2

Selleck's Moxifloxacin has been cited by 4 Publications

Purity & Quality Control

Choose Selective Bacterial Inhibitors

Biological Activity

Description Moxifloxacin is an antibiotic used to treat a number of bacterial infections, active against Mycobacterium tuberculosis in vitro.

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 24 mg/mL
(59.78 mM)
Ethanol ''-1 mg/mL

Chemical Information

Molecular Weight 401.43
Formula

C21H24FN3O4

CAS No. 151096-09-2
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles COC1=C2C(=CC(=C1N3CC4CCCNC4C3)F)C(=O)C(=CN2C5CC5)C(=O)O

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % ddH2O
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT04239326 Recruiting Diagnostic Test: targeted Next Generation Sequencing (tNGS) Tuberculosis Multidrug-Resistant Foundation for Innovative New Diagnostics Switzerland April 16 2021 --
NCT04563845 Completed Drug: GSK3640254|Drug: Placebo|Drug: Moxifloxacin HIV Infections ViiV Healthcare November 9 2020 Phase 1

(data from https://clinicaltrials.gov, updated on 2022-01-17)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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