For research use only.

Catalog No.S1845 Synonyms: SKF-92334

4 publications

Cimetidine  Chemical Structure

CAS No. 51481-61-9

Cimetidine (SKF-92334), a histamine congener, competitively inhibits histamine binding to histamine H2 receptors.

Selleck's Cimetidine has been cited by 4 publications

Purity & Quality Control

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Biological Activity

Description Cimetidine (SKF-92334), a histamine congener, competitively inhibits histamine binding to histamine H2 receptors.
Histamine H2 receptor [1]



Solubility (25°C)

In vitro DMSO 51 mg/mL (202.1 mM)
Ethanol 3 mg/mL (11.88 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 252.34


CAS No. 51481-61-9
Storage powder
in solvent
Synonyms SKF-92334

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
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Step 2: Enter the in vivo formulation ()
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Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

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  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
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Molecular Weight Calculator

Molecular Weight Calculator

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT01536249 Completed Drug: Dexpramipexole|Drug: Cimetidine plus Dexpramipexole Amyotrophic Lateral Sclerosis Knopp Biosciences March 2012 Phase 1
NCT01169012 Completed Drug: Clofarabine Myelodysplastic Syndrome|Acute Myeloid Leukemia|Acute Lymphoblastic Leukemia|Chronic Myelomonocytic Leukemia UNC Lineberger Comprehensive Cancer Center|Genzyme a Sanofi Company September 2010 Phase 1
NCT00475059 Completed Drug: cimetidine arrow Kidney Transplantation Centre Hospitalier Universitaire de Saint Etienne March 2007 Not Applicable
NCT01366378 Completed Drug: methylnaltrexone Healthy Adult Subjects Bausch Health Americas Inc. January 2007 Phase 1
NCT00244530 Completed Drug: Nifedipine Kidney Failure Chronic|Coronary Artery Disease University of Oslo School of Pharmacy June 2001 Phase 4

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Histamine Receptor Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID