Acetylcholine Chloride

Catalog No.S1805

For research use only.

The chemical compound Acetylcholine Chloride is a neurotransmitter in both the peripheral nervous system (PNS) and central nervous system (CNS) in many organisms including humans.

Acetylcholine Chloride Chemical Structure

CAS No. 60-31-1

Selleck's Acetylcholine Chloride has been cited by 1 Publication

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Biological Activity

Description The chemical compound Acetylcholine Chloride is a neurotransmitter in both the peripheral nervous system (PNS) and central nervous system (CNS) in many organisms including humans.
Targets
AChR [1]

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 36 mg/mL
(198.17 mM)
Water 36 mg/mL
(198.17 mM)
Ethanol '36 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 181.66
Formula

C7H16NO2.Cl

CAS No. 60-31-1
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC(=O)OCC[N+](C)(C)C.[Cl-]

In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05147337 Recruiting Drug: E2511|Drug: Placebo Healthy Volunteers Eisai Inc. December 1 2021 Phase 1
NCT05095103 Not yet recruiting -- Myasthenia Gravis University of Manchester|Salford Royal NHS Foundation Trust|Walton Centre NHS Foundation Trust|Oxford University Hospitals NHS Trust|University College London Hospitals|University Hospital Birmingham NHS Foundation Trust|Imperial College Healthcare NHS Trust|Newcastle-upon-Tyne Hospitals NHS Trust|King''s College Hospital NHS Trust|Nottingham University Hospitals NHS Trust|University Hospital Southampton NHS Foundation Trust|Cardiff University October 2021 --
NCT04833894 Recruiting Biological: Efgartigimod IV Generalized Myasthenia Gravis argenx October 26 2021 Phase 2|Phase 3
NCT04818671 Recruiting Biological: efgartigimod PH20 SC Generalized Myasthenia Gravis argenx April 26 2021 Phase 3
NCT04735432 Active not recruiting Biological: efgartigimod PH20 SC|Biological: efgartigimod IV Generalized Myasthenia Gravis argenx February 5 2021 Phase 3

(data from https://clinicaltrials.gov, updated on 2022-01-17)

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