AZD8055

Catalog No.S1555

Molecular Weight(MW): 465.54

AZD8055 is a novel ATP-competitive mTOR inhibitor with IC50 of 0.8 nM in MDA-MB-468 cells with excellent selectivity (∼1,000-fold) against PI3K isoforms and ATM/DNA-PK. Phase 1.

Cited by 40 Publications

Nat Med, 2015, 10.1038/nm.3855

PubMed: 25939062

Cancer Res, 2018, 78(12):3176-3189

PubMed: 29661831

Cancer Cell, 2015, 27(1):97-108

PubMed: 25544637

Cancer Cell, 2015, 27(4):533-46

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J Clin Invest, 2014, 10.1172/JCI73935

PubMed: 25415435

Genome Biol, 2016, 17(1):149

PubMed: 27380875

Nat Commun, 2014, 5:3384

PubMed: 24594970

Autophagy, 2012, 9(1):74-92

PubMed: 23196898

Cancer Res, 2015, 75(20):4398-406

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Cancer Res, 2014, 74(10):2846-56

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Cancer Res, 2014, 74(14):3947-58

PubMed: 24986516

Cancer Res, 2013, 73(11):3402-11

PubMed: 23585456
Cell Rep, 2015, 11(3):446-59

PubMed: 25865887

Int J Cancer, 2014, 10.1002/ijc.28880

PubMed: 24706460

Antioxid Redox Sign, 2014, 20(9):1382-95

PubMed: 24063548

Am J Transplant, 2013, 13(8):2035-43

PubMed: 23841834

Mol Cancer Ther, 2013, 13(1):37-48

PubMed: 24233399

Cell Commun Signal, 2017, 10.1186/s12964-017-0164-3

PubMed: 28143584

Mol Oncol, 2013, 33:404-18

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Mol Cell Proteomics, 2014, 13(6):1429-38

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Clin Sci, 2015, 128(8):517-26

PubMed:

Mol Cancer Res, 2015, 13(2):223-30

PubMed:

Mol Cancer Res, 2015, 13(1):120-9

PubMed:

Exp Neurol, 2012, 233(2):799-806

PubMed: 22177999
Biochem Pharmacol, 2012, 83(9):1183-94

PubMed: 22305748

J Biol Chem, 2015, 10.1074/jbc.C114.627778

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J Biol Chem, 2013, 288(49):35287-96

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Am J Cancer Res, 2014, 4(6):824-837

PubMed:

Biochem J, 2015, 465(2):227-38

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Mol Cell Biol, 2014, 34(13):2517-32

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J Chromatogr A, 2015, 1388:267-73

PubMed:

Proteomics, 2015, 10.1002/pmic.201400586

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Mol Biol Cell, 2013, 24(23):3736-45

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Mol Reprod Dev, 2014, 81(7):655-65

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PLoS One, 2016, 11(4):e0154564

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PLoS One, 2013, 8(2):e56567

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Biochem Biophys Res Commun, 2013, 440(4):701-6

PubMed: 24103749

Oncol Lett, 2013, 5(2):717-721

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Oncotarget, 2014, 5(21):10732-44

PubMed: 25313141

Oncotarget, 2014, 5(15):6015-27

PubMed: 24970798

8 Customer Reviews

PC3-LN4 cells were treated with GSK690693 (5 uM) alone, or in combination with PP242 (2 uM) or AZD8055 (1 uM) for 24 h, and immunoblotting performed.

Cancer Res 2013 73(11), 3402-11. AZD8055 purchased from Selleck.

mTOR kinase inhibitor AZD8055 activates PI3K accompanied with induction of expression of EGFR, HER2, HER3 and IRS1. Serum-deprived CHO-EGFP-AKT cells were incubated with 50 nM AZD8055 for 24 hr. The EGFP signal was detected using confocal microscopy. The white arrows indicate EGFP-AKT located on cellular membrane.

Int J Cancer 2014 135(10), 2462-74. AZD8055 purchased from Selleck.
HUVEC were treated with either RAD001 or AZD8055 before PA treatment. p53, GPX1, p53 acetylation, and subcellular PTEN were analyzed with corresponding antibodies. The blot is a representative of the results of three experiments. Values (mean盨D) are expressed as fold over untreated control. *p<0.05 versus their corresponding control groups in the one-way ANOVA.

Antioxid Redox Signal 2014 20(9), 1382-95. AZD8055 purchased from Selleck.

CSCs^+24/44/ESA at 5,000 cells per well with stem cell culture media in triplicate in an ultra-low adhesion plate were treated with 5 umol/L BMS-777607, 1 umol/L AZD8055 alone, or in their different combinations. Cells were cultured for 72 hours. Cell viability was determined by the MTS assay. Percentages of polyploid cells were determined by counting 300 cells from two different regions. Results shown here were from one of two experiments with similar results.

Mol Cancer Ther 2014 13(1), 37-48. AZD8055 purchased from Selleck.
mTOR, P70S6K1, 4E-BP1 and PCNA activation in the basilar artery of SAH. Top, Western blotting bands of antibodies, bottom, density of the protein band from each group. A, mTOR activation in the basilar artery demonstrated an elevated expression of mTOR on day 7 following SAH in SAH and SAH+DMSO animals. The mTOR inhibitors, Rapamycin and AZD8055 reduced the enhanced expression of mTOR (pb0.05, ANOVA). B. P70S6K1 activation. C. 4E-BP1 activation. D. PCNA activation. Rapamycin and AZD8055 significantly decreased the expression of P70S6K1, 4E-BP1 and PCNA compared with the SAH and SAH+DMSO (pb0.05, respectively; ANOVA). There was no significant difference between the two inhibitors in mTOR, P70S6K1, 4E-BP1 and PCNA expression.

Exp Neurol 2012 233, 799-806. AZD8055 purchased from Selleck.

Induction of TCTP expression through 5-FU or oxaliplatin is inhibited by mTOR kinase inhibitors. HCT116 cells were treated for 48 h with 5-FU or oxaliplatin at the indicated concentrations. Where indicated, AZD 8055 (100 nM) or PP242 (1 μM) were added. TCTP levels were assessed by western blotting; signals were quantified and normalised against α-tubulin as a loading control. As a readout of mTOR activity, phosphorylation of the ribosomal protein S6 at Ser 240/244 was assessed using a phospho-specific antibody. a. Representative western blots demonstrating the alteration of the levels of TCTP protein and of phospho-ribosomal protein S6, respectively, in relation to the drug concentration.

Cell Commun Signal, 2017, 15(1):9. AZD8055 purchased from Selleck.
(A) HCT116 or MDA-MB-468 cells were treated with 500 nM AZD8055 for the indicated times. Cell lysates were immunoblotted with the indicated antibodies. (B) HCT116 or MDA-MB-468 cells were treated with 50 nM rapamycin. 500 nM AZD8055, 1 uM MK2206 or dimethyl sulfoxide (DMSO) as control for 12 h. Cell lysates were immunoblotted with the indicated antibodies.

Oncotarget 2014 5(15), 6015-27. AZD8055 purchased from Selleck.

After starved in serum-free medium for 24h , A549 cells incubated with the indicated concentrations of AZD8055 for 3h , followed by 20-minute stimolation of 100ng/ml EGF

Dr. Zhang of Tianjin Medical University. AZD8055 purchased from Selleck.

Purity & Quality Control

Choose Selective mTOR Inhibitors

Biological Activity

Description

AZD8055 is a novel ATP-competitive mTOR inhibitor with IC50 of 0.8 nM in MDA-MB-468 cells with excellent selectivity (∼1,000-fold) against PI3K isoforms and ATM/DNA-PK. Phase 1.

Features

First drug to inhibit both types of mTOR protein.

Targets

mTOR (truncated) ^[1] (MDA-MB-468 cells)	mTOR (full length) ^[1] (MDA-MB-468 cells)
0.13 nM	0.8 nM

In vitro

AZD8055 shows low activity (∼1,000-fold) against all PI3K isoforms (α, β, γ, δ) and other members of the PI3K-like kinase family (ATM and DNA-PK). AZD8055 inhibits the phosphorylation of mTORC1 (p70S6K and 4E-BP1) as well as phosphorylation of the mTORC2 (Akt) and downstream proteins. The rapamycin-resistant T37/46 phosphorylation sites on 4E-BP1 can be fully inhibited by AZD8055, resulting in significant inhibition of cap-dependent translation. AZD8055 potently inhibits proliferation in U87MG, A549 and H838 cells with IC50 of 53, 50 and 20 nM, respectively. AZD8055 also induces autophagy and increased LC3-II levels in H838 and A549 cells. ^[1] AZD8055 decreases AML blast cell proliferation and cell cycle progression, reduces the clonogenic growth of leukemic progenitors and induces caspase-dependent apoptosis in leukemic cells but not in normal immature CD34+ cells. ^[2] AZD8055 indicates inhibitory against the pediatric preclinical testing program (PPTP) cell lines with IC50 of 24.7 nM and induces significant differences in EFS distribution. ^[3]

Cell Data

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID
LU-139	NEjrVplIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NVXxd4lQUUN3ME2wMlAzOzNzIN88US=>	M{PRVHNCVkeHUh?=
NCI-H720	M4LYdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NFTRVnVKSzVyPUCuNFI6OzhizszN	MYjTRW5ITVJ?
KARPAS-45	NHXTdoNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MV\JR\|UxRTBwMEOzO\|Eh\|ryP	M364eXNCVkeHUh?=
EW-3	M{S1WWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MVvJR\|UxRTBwMESwOVYh\|ryP	MnSxV2FPT0WU
SBC-1	NEjGbGxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NWizV2pJUUN3ME2wMlA1PThzIN88US=>	NUezPWF6W0GQR1XS
NCI-H209	MUHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M1\sTGlEPTB;MD6wOVQ2OyEQvF2=	NULi[4lIW0GQR1XS
EoL-1-cell	NVvVW4NJT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NWjCc5pUUUN3ME2wMlA3PTZ7IN88US=>	NHLXV4hUSU6JRWK=
H9	M{\BTmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MYrJR\|UxRTBwME[2PVIh\|ryP	MnLrV2FPT0WU
AN3-CA	MXzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M3K2cmlEPTB;MD6wO\|k2OSEQvF2=	MnHjV2FPT0WU
HH	MnztS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NXO0fnBMUUN3ME2wMlA5ODB7IN88US=>	MlPNV2FPT0WU
KU812	NYjwOVVzT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M4PVe2lEPTB;MD6wPFA1OyEQvF2=	MV\TRW5ITVJ?
DU-4475	NWjuOoVqT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NH3DdGFKSzVyPUCuNFgxPDdizszN	NFPN[YtUSU6JRWK=
CTV-1	NH3DU5RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MoHRTWM2OD1yLkC4OlQyKM7:TR?=	NVvJUnhqW0GQR1XS
BV-173	NFnoUWFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NWfROVFzUUN3ME2wMlA6ODZzIN88US=>	NYT3TlZ3W0GQR1XS
ES5	NFHheVJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NH71V2pKSzVyPUCuNFk{PSEQvF2=	M4HHOnNCVkeHUh?=
G-402	MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MVfJR\|UxRTBwMEm5PEDPxE1?	MXjTRW5ITVJ?
MV-4-11	MoHLS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				Mn;VTWM2OD1yLkGwN\|Q4KM7:TR?=	NIfsPY5USU6JRWK=
NB69	Ml7RS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M4THTGlEPTB;MD6xN\|Uh\|ryP	NGTFTFBUSU6JRWK=
EGI-1	NWj3RYRWT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NVTIZphEUUN3ME2wMlE{PTNzIN88US=>	M4fU[3NCVkeHUh?=
EW-18	NVfmR\|ZPT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MmK5TWM2OD1yLkG0NFc{KM7:TR?=	M4L2OXNCVkeHUh?=
ME-180	NHzHbFRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NUHBWFRiUUN3ME2wMlE1PjhzIN88US=>	MU\TRW5ITVJ?
D-283MED	NFfsW\|BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NFrLRnhKSzVyPUCuNVQ4OjNizszN	NILrcHJUSU6JRWK=
NB14	MUTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NITwW3dKSzVyPUCuNVY1PDdizszN	NFH0T\|JUSU6JRWK=
Ramos-2G6-4C10	MoDIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				Mor5TWM2OD1yLkG2PVg{KM7:TR?=	M3\Y[nNCVkeHUh?=
NBsusSR	MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NV\WcotLUUN3ME2wMlE4ODF7IN88US=>	M3W0[HNCVkeHUh?=
LAMA-84	NETlNWxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M1vJTWlEPTB;MD6xPFA{OiEQvF2=	NHPmTZdUSU6JRWK=
NCI-H1581	MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NWPQTWlLUUN3ME2wMlE5QTZ4IN88US=>	Mmr6V2FPT0WU
A204	MlrvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MmT2TWM2OD1yLkG4PVch\|ryP	MoewV2FPT0WU
A549	MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MXTJR\|UxRTBwMUm1OUDPxE1?	NUXucFk4W0GQR1XS
CAL-51	M3f3WGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				Mn7VTWM2OD1yLkG5OlUyKM7:TR?=	MlPNV2FPT0WU
NKM-1	MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NHXaTnNKSzVyPUCuNlAxOjlizszN	NWqxOYFTW0GQR1XS
LoVo	NITHeVJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MnfOTWM2OD1yLkKwNlAzKM7:TR?=	NF3EWHNUSU6JRWK=
HAL-01	NIDUcYVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NEHPOYFKSzVyPUCuNlAzQTdizszN	M2T6cHNCVkeHUh?=
HCC2218	MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NHniTZpKSzVyPUCuNlA3QDhizszN	NX\ZRYNWW0GQR1XS
BEN	MkfSS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MULJR\|UxRTBwMkGyPVMh\|ryP	MlHTV2FPT0WU
LC-2-ad	MknIS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MlPnTWM2OD1yLkKyNFg1KM7:TR?=	NWPP[WxTW0GQR1XS
LXF-289	NFP2coNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NVX2RYxZUUN3ME2wMlI2ODRzIN88US=>	NIDHPGJUSU6JRWK=
HGC-27	NYXaN2I6T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M1n3U2lEPTB;MD6yOlQyPCEQvF2=	MX\TRW5ITVJ?
LK-2	Mlj4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MW\JR\|UxRTBwMk[4NlQh\|ryP	NIX6ZYVUSU6JRWK=
CTB-1	MlTwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NUDLeWRwUUN3ME2wMlI4OjF3IN88US=>	M3G1fHNCVkeHUh?=
697	NVfKR2pIT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MU\JR\|UxRTBwMkezOlch\|ryP	MYPTRW5ITVJ?
ES7	NF;GUZdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MXzJR\|UxRTBwMkezPFMh\|ryP	MXzTRW5ITVJ?
MG-63	MlXOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MYrJR\|UxRTBwMke0NFch\|ryP	MVrTRW5ITVJ?
T47D	M2DWVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NIqxUlRKSzVyPUCuNlc1PzVizszN	MVzTRW5ITVJ?
RPMI-8226	NFTkRZlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MWHJR\|UxRTBwMki1PFkh\|ryP	M33iO3NCVkeHUh?=
NCI-H292	MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M3zkSGlEPTB;MD6yPVE3PCEQvF2=	M4n5UnNCVkeHUh?=
HT	MV;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NUPY[ndDUUN3ME2wMlI6OzhizszN	Mn:xV2FPT0WU
A3-KAW	MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M2jLO2lEPTB;MD6yPVc1KM7:TR?=	MXTTRW5ITVJ?
LB2241-RCC	MnrvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M3rFNGlEPTB;MD6zNFE6QCEQvF2=	NEjEXXZUSU6JRWK=
BB65-RCC	NHSxeJpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NWX0e4dZUUN3ME2wMlMxQDB3IN88US=>	Mn76V2FPT0WU
G-401	M3zRc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MoW2TWM2OD1yLkOwPVg3KM7:TR?=	NYX0bmFRW0GQR1XS
TYK-nu	MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NYP0fpJwUUN3ME2wMlMyQDZ2IN88US=>	NWDtSHo3W0GQR1XS
NCI-SNU-1	NFHnboVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MYXJR\|UxRTBwM{KzN\|Eh\|ryP	NGf6N4tUSU6JRWK=
CHL-1	M1\qdmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M3O2bmlEPTB;MD6zNlcxOyEQvF2=	M333[HNCVkeHUh?=
P30-OHK	MnKwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M1vtU2lEPTB;MD6zNlcxPSEQvF2=	NYnwXHZrW0GQR1XS
PA-1	M3\VUGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MV7JR\|UxRTBwM{O2NVkh\|ryP	M3Tz[nNCVkeHUh?=
LB1047-RCC	MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MWnJR\|UxRTBwM{SwOFch\|ryP	NWHScmtKW0GQR1XS
EM-2	MkLPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NWnuN2gyUUN3ME2wMlM1OTh6IN88US=>	MXvTRW5ITVJ?
VA-ES-BJ	MYHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NF3RR3pKSzVyPUCuN\|QzPjhizszN	NX3PU402W0GQR1XS
NCI-H520	MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NWi1XWhIUUN3ME2wMlM1QDN2IN88US=>	NVq1VIQzW0GQR1XS
ECC10	MWnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NWHDT4RjUUN3ME2wMlM2ODN3IN88US=>	NVS0OGNDW0GQR1XS
LNCaP-Clone-FGC	MVzHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				Ml7rTWM2OD1yLkO1N\|E1KM7:TR?=	M1vwdHNCVkeHUh?=
ES8	NUnGbmp4T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				Mn;MTWM2OD1yLkO2OVU{KM7:TR?=	NVXj[oloW0GQR1XS
HuO-3N1	MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MlSzTWM2OD1yLkO4N\|c6KM7:TR?=	M{HXbHNCVkeHUh?=
L-363	NInn[pBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MYfJR\|UxRTBwM{mwNlYh\|ryP	M2qyUnNCVkeHUh?=
SK-LU-1	MontS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NFT5bpFKSzVyPUCuN\|kzODhizszN	M1S3NXNCVkeHUh?=
MCF7	NUnqSHo4T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NX3lVnJ6UUN3ME2wMlQxPTNizszN	MmDYV2FPT0WU
HuO9	MleyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NWP1dpRDUUN3ME2wMlQxPjZ5IN88US=>	MVLTRW5ITVJ?
BHT-101	NU\2Z4xGT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MmLYTWM2OD1yLkSwO\|g4KM7:TR?=	NHW3c4VUSU6JRWK=
MZ2-MEL	Mn;hS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M3nTOWlEPTB;MD60NFg5OiEQvF2=	Mk\ZV2FPT0WU
NOS-1	NHHtN5hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NX[4b2JPUUN3ME2wMlQyODd2IN88US=>	M{TrS3NCVkeHUh?=
NEC8	MoLqS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M{j0cWlEPTB;MD60NVY6PSEQvF2=	MVfTRW5ITVJ?
COR-L88	MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MWDJR\|UxRTBwNEKyOlch\|ryP	M4fs[nNCVkeHUh?=
MFM-223	M1nnd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M{DM[2lEPTB;MD60NlYyPyEQvF2=	M{[wT3NCVkeHUh?=
HSC-3	NX7Ob21IT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M1;MU2lEPTB;MD60NlkxQCEQvF2=	NIfWeVBUSU6JRWK=
OVCAR-5	NGnIcnZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MkXyTWM2OD1yLkSyPVM{KM7:TR?=	M3ns[3NCVkeHUh?=
MFE-280	MlzJS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NXH3bGNqUUN3ME2wMlQ{ODN{IN88US=>	MVzTRW5ITVJ?
KP-N-YS	NEiyO\|hIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NXnX[XhuUUN3ME2wMlQ{ODdizszN	NGPqcopUSU6JRWK=
EPLC-272H	MmXpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NVfpWXZ1UUN3ME2wMlQ{ODd5IN88US=>	M2T0VHNCVkeHUh?=
KE-37	NGjVPIlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M3mxR2lEPTB;MD60N\|I1PyEQvF2=	NWm5Tm5WW0GQR1XS
HuH-7	Mn76S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				Ml7xTWM2OD1yLkSzN\|czKM7:TR?=	NFLjcYNUSU6JRWK=
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NCI-H460	NWqyNpZIT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				Mly4TWM2OD1yLkWwOVk4KM7:TR?=	NYXqNmNJW0GQR1XS
MDA-MB-361	Mk\3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MWLJR\|UxRTBwNUC4O{DPxE1?	NX2xR2NZW0GQR1XS
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NCI-H1648	NE[z[VVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MorFTWM2OD1yLkewNVc{KM7:TR?=	NWfKc2U3W0GQR1XS
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NCI-H1623	MmnGS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M1XXPWlEPTB;MD63OlI3OSEQvF2=	Mo\1V2FPT0WU
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KYSE-140	M3TYNGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M4P5WWlEPTB;MD63PFE3QCEQvF2=	M4nUTnNCVkeHUh?=
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NCI-H1563	MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MX;JR\|UxRTBwN{i5NlYh\|ryP	MlzrV2FPT0WU
NCI-H650	MlzrS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NV;LSWJPUUN3ME2wMlc6OTR2IN88US=>	M4fw[3NCVkeHUh?=
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CAL-62	MX7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NWrsfXNTUUN3ME2wMlc6QTJ2IN88US=>	M2DTNHNCVkeHUh?=
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NCI-H2347	NF3mbJRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MoTNTWM2OD1yLkiyOFAyKM7:TR?=	NYj4bGF2W0GQR1XS
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KYSE-450	MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NX7WXmZiUUN3ME2wMlgzPzJ3IN88US=>	MojoV2FPT0WU
PFSK-1	NGK0fllIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MV3JR\|UxRTBwOEOwN\|kh\|ryP	M2r4OnNCVkeHUh?=
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HD-MY-Z	M2rmSGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M{TEWWlEPTB;MD64OFA6OiEQvF2=	NX34[HpHW0GQR1XS
RT-112	MlG3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NX\GfGxXUUN3ME2wMlg1QTN5IN88US=>	M3ni[HNCVkeHUh?=
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RPMI-8866	MVLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MYjJR\|UxRTBwOEW4NlIh\|ryP	MkW4V2FPT0WU
CAL-120	MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M3vrVWlEPTB;MD64OlA1OSEQvF2=	NG[xXFRUSU6JRWK=
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NCI-H1573	NF7mSYRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NHvjbndKSzVyPUCuPVAzOjlizszN	NF3vWY5USU6JRWK=
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MIA-PaCa-2	MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NUfDZ4k{UUN3ME2wMlkzQTJ{IN88US=>	M1fCdnNCVkeHUh?=
HCC1806	MoDDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MVrJR\|UxRTBwOUOyOVYh\|ryP	M3fkfXNCVkeHUh?=
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NCI-H1792	NIT2WWxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NIX3clRKSzVyPUCuPVcyODFizszN	NFPUelRUSU6JRWK=
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KYSE-180	NEC0XGNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NGfSco1KSzVyPUGuNVExOjFizszN	MYLTRW5ITVJ?
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NCI-H1092	NYfjWGJvT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MUDJR\|UxRTFwMUO0JO69VQ>?	M1LO[HNCVkeHUh?=
NCI-H1755	MmPkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NUfRS5pHUUN3ME2xMlE{QTRzIN88US=>	NIHYVJBUSU6JRWK=
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NCI-H2405	M{LNe2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NX7l[Y9SUUN3ME2xMlE1PTd2IN88US=>	M2fZRnNCVkeHUh?=
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MDA-MB-453	Mn;sS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MVHJR\|UxRTFwMUW2NlQh\|ryP	M2jvZ3NCVkeHUh?=
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Detroit562	NVvlUWFKT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NIn3Z3FKSzVyPUGuNVk1OzlizszN	NUf1d2FGW0GQR1XS
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HDLM-2	M4nQN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MV;JR\|UxRTFwMkGzNlYh\|ryP	MoW5V2FPT0WU
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MDA-MB-415	MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NEGxTVFKSzVyPUGuNlE4ODJizszN	NXrGeY9WW0GQR1XS
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NCI-H2030	NVLN[VdxT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MUnJR\|UxRTFwMkSxNFYh\|ryP	NYe3NZFkW0GQR1XS
LS-123	Mle3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MlqyTWM2OD1zLkK0O\|U{KM7:TR?=	NIfFcmdUSU6JRWK=
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NCI-H596	NHTkfZVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				Mk\QTWM2OD1zLkK1PVI6KM7:TR?=	MXjTRW5ITVJ?
KYSE-410	NFm4UIZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NFjC[G1KSzVyPUGuNlcxOTRizszN	NFiyNXdUSU6JRWK=
NCI-H2228	MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M3XaW2lEPTB;MT6yO\|E3PyEQvF2=	MWnTRW5ITVJ?
LN-405	NInqeWhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MoH0TWM2OD1zLkK4NFIyKM7:TR?=	MVXTRW5ITVJ?
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BFTC-909	MlnZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M2PUd2lEPTB;MT6yPVQ{PCEQvF2=	MmPmV2FPT0WU
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GAK	MmDmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MVvJR\|UxRTFwM{G4OVgh\|ryP	MmG0V2FPT0WU
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NCI-H446	NVvObXlxT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MknCTWM2OD1zLkOyPVAzKM7:TR?=	MorDV2FPT0WU
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GCT	NFnmOoVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NYXSVnBYUUN3ME2xMlM1OzR3IN88US=>	Moq3V2FPT0WU
COR-L23	MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NEnFcFZKSzVyPUGuN\|Q5PDVizszN	NX6wTWgxW0GQR1XS
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AM-38	M1vmOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NWK5bXRCUUN3ME2xMlM4OTl7IN88US=>	M4HDSHNCVkeHUh?=
CHP-134	MlXDS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NVvESVRXUUN3ME2xMlM4QDR2IN88US=>	MorDV2FPT0WU
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LB831-BLC	MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NETsWYJKSzVyPUGuN\|kxPjdizszN	NGXERYRUSU6JRWK=
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LCLC-97TM1	MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NGL6VolKSzVyPUGuOFExPDZizszN	M2nMdHNCVkeHUh?=
HCT-116	NX7KXnN6T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MXvJR\|UxRTFwNEK4OVQh\|ryP	NFPi[lVUSU6JRWK=
ALL-PO	NIPU[HNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				Mo\XTWM2OD1zLkSzO\|c1KM7:TR?=	M2nKV3NCVkeHUh?=
EW-16	MoD5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MlPmTWM2OD1zLkSzPFQzKM7:TR?=	MmLuV2FPT0WU
NCI-H661	NV;TPWE2T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NX\QWWd{UUN3ME2xMlQ1Pzd3IN88US=>	MV3TRW5ITVJ?
TE-8	MkDMS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MonqTWM2OD1zLkS1OVYh\|ryP	MnXPV2FPT0WU
TCCSUP	MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MkjNTWM2OD1zLkS2PVYh\|ryP	MkK3V2FPT0WU
SW1990	MnjiS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NIfBUWRKSzVyPUGuOFc2OzNizszN	MnraV2FPT0WU
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NCI-H1299	MVjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M4\YfmlEPTB;MT61NFA5PiEQvF2=	NVHFVoxsW0GQR1XS
RO82-W-1	MUPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MkS4TWM2OD1zLkWyNFgyKM7:TR?=	NULhUGhlW0GQR1XS
Becker	NIjvdWtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NYnPN3lIUUN3ME2xMlUzOTh5IN88US=>	Mn7BV2FPT0WU
SNU-387	MVXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NVPOc3N7UUN3ME2xMlUzOjRzIN88US=>	MkW3V2FPT0WU
CAL-85-1	NVTsdGx4T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MmPkTWM2OD1zLkWyOVk6KM7:TR?=	MUPTRW5ITVJ?
647-V	NWHXOVhCT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M3j0PGlEPTB;MT61N\|g5KM7:TR?=	MUPTRW5ITVJ?
SBC-5	MUnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M1Xt[2lEPTB;MT61OFU6OyEQvF2=	MU\TRW5ITVJ?
NCI-H23	NFjZcYtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MnLvTWM2OD1zLkW1O\|E1KM7:TR?=	MWjTRW5ITVJ?
CGTH-W-1	Mn;CS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MXfJR\|UxRTFwNUW4NVkh\|ryP	NFPuXodUSU6JRWK=
SK-N-FI	NFLS[opIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NUDu[nZyUUN3ME2xMlU2QTB6IN88US=>	M2jz[HNCVkeHUh?=
KM-H2	MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M1fpVWlEPTB;MT61OlQ4PCEQvF2=	MnfDV2FPT0WU
KY821	Mn;yS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NXjyWHJXUUN3ME2xMlU3PjF5IN88US=>	MWPTRW5ITVJ?
RH-1	NITDTGxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NGK2N3RKSzVyPUGuOVY4PjJizszN	NHm3OFRUSU6JRWK=
KYSE-270	NVPBXVFGT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MUXJR\|UxRTFwNUe0NlMh\|ryP	M1jJXnNCVkeHUh?=
SF539	NWPKN\|kzT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M3LGUGlEPTB;MT61O\|k3QSEQvF2=	NEHhdW5USU6JRWK=
JEG-3	MlqxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MmDnTWM2OD1zLkW4NFk1KM7:TR?=	M1ruTnNCVkeHUh?=
SCC-25	NVTDUVZFT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NETUcmlKSzVyPUGuOVg1OzJizszN	NHiwNZFUSU6JRWK=
SW1573	MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MX3JR\|UxRTFwNkCxOVgh\|ryP	M{jYUHNCVkeHUh?=
EW-1	NVPkcYdTT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M3;temlEPTB;MT62NVM2OSEQvF2=	MmrzV2FPT0WU
YKG-1	M2\Ucmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NHzUU4dKSzVyPUGuOlE1OzhizszN	M3zRUXNCVkeHUh?=
EW-11	NWDoTpQ{T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M4j5VWlEPTB;MT62NVc1OSEQvF2=	MnzRV2FPT0WU
DJM-1	NHHjToFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MlXwTWM2OD1zLk[xPFI2KM7:TR?=	NYK2fGd6W0GQR1XS
Calu-3	MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NGTNTVBKSzVyPUGuOlUzOTNizszN	NHPwS3VUSU6JRWK=
HT-3	M1HhZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M1\3fWlEPTB;MT62OVY3KM7:TR?=	NXi5SG1WW0GQR1XS
NCI-H69	M3rDSmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NF\VNHJKSzVyPUGuOlc{PDNizszN	Ml;XV2FPT0WU
NCI-H2126	Mn7QS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MkLPTWM2OD1zLk[3O\|k4KM7:TR?=	NGnXZ3FUSU6JRWK=
RPMI-2650	M2\jbGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NETVUoxKSzVyPUGuOlg{OTdizszN	NUPJbXBxW0GQR1XS
TE-6	NVva[WFCT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NYTOWnUzUUN3ME2xMlcxQDd2IN88US=>	MYDTRW5ITVJ?
MDA-MB-231	NFjp[ndIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NE\JSZJKSzVyPUGuO\|E6QTNizszN	NVfLdXhHW0GQR1XS
A2780	M4XnS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				Mnu5TWM2OD1zLkeyNlA4KM7:TR?=	NGn0eZNUSU6JRWK=
GOTO	Ml6yS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NIPkZoNKSzVyPUGuO\|M2PiEQvF2=	M1TmXHNCVkeHUh?=
KYSE-70	Mm\yS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NYfSdIxFUUN3ME2xMlc1PDR{IN88US=>	M3LnUHNCVkeHUh?=
GMS-10	Mn\ZS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NXy2fpJoUUN3ME2xMlc1PjZ{IN88US=>	NInZNnZUSU6JRWK=
CaR-1	MkXmS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MlfNTWM2OD1zLke0PFEzKM7:TR?=	MUXTRW5ITVJ?
SW900	NVP6R3lLT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MojFTWM2OD1zLke0PVk{KM7:TR?=	M{X1cXNCVkeHUh?=
BB49-HNC	MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MUfJR\|UxRTFwN{WxOlgh\|ryP	MUjTRW5ITVJ?
SNB75	NWjBWlZFT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NEfTdZhKSzVyPUGuO\|U1QTJizszN	MVjTRW5ITVJ?
SK-PN-DW	NF\NfVNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NILNVXhKSzVyPUGuO\|U3QDJizszN	MlLlV2FPT0WU
5637	NF[wSFBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NF64W2xKSzVyPUGuO\|czPjhizszN	M2Xwe3NCVkeHUh?=
BT-474	M4SwN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MV7JR\|UxRTFwN{ixO\|Eh\|ryP	NVTrVnpHW0GQR1XS
KM12	NYP1NIJ1T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NU\wVYZLUUN3ME2xMlc6PzRzIN88US=>	MkTKV2FPT0WU
COLO-680N	M3u3fmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M3jFUGlEPTB;MT64NlM5OSEQvF2=	M3H0d3NCVkeHUh?=
Saos-2	M1:2d2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NGjXT29KSzVyPUGuPFI1PDVizszN	NHjod2VUSU6JRWK=
CAL-54	MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MojjTWM2OD1zLkizN\|E{KM7:TR?=	MYLTRW5ITVJ?
U-118-MG	NF\KeYtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NF3VWVhKSzVyPUGuPFQ3OjJizszN	Ml7YV2FPT0WU
TGBC24TKB	NVnPRoRkT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NHnTS3ZKSzVyPUGuPFU2ODFizszN	NVXTUo1vW0GQR1XS
NCI-H2052	NEf6XXFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				Mn7VTWM2OD1zLki2OFEh\|ryP	MmjCV2FPT0WU
BB30-HNC	MY\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MXHJR\|UxRTFwOE[0OlIh\|ryP	NEnadpVUSU6JRWK=
KNS-81-FD	NE\VN3lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MXTJR\|UxRTFwOEmxOlUh\|ryP	M{nCeXNCVkeHUh?=
HN	MVfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M3jpZ2lEPTB;MT64PVU1PSEQvF2=	MV;TRW5ITVJ?
ACHN	M1\WVWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MYDJR\|UxRTFwOUC3PFYh\|ryP	MWXTRW5ITVJ?
HSC-2	Ml;3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MVzJR\|UxRTFwOUGwPVYh\|ryP	M3HDeXNCVkeHUh?=
HCC2998	NIroVWxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NGG5cXRKSzVyPUGuPVM{OjVizszN	MWPTRW5ITVJ?
HEL	M3zVR2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NGPkRoNKSzVyPUGuPVQyQDRizszN	M4T1VHNCVkeHUh?=
SW684	NVPabGlET3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NEPzZmFKSzVyPUGuPVc{PzFizszN	NWG0epJLW0GQR1XS
NCI-H1693	NUXURXF5T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NGX2cFJKSzVyPUGuPVgxQDZizszN	NV3nTY1mW0GQR1XS
8-MG-BA	MknTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NVuxblZ5UUN3ME2xMlk5OjFizszN	NUm3O5VMW0GQR1XS
OVCAR-8	NIHJT\|RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M3SzOmlEPTB;Mj6wNFI6PSEQvF2=	NWjY[GJbW0GQR1XS
DSH1	NESwfopIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NEDoT5pKSzVyPUKuNFE4PzRizszN	NX3hN2V3W0GQR1XS
KYSE-520	NH3LVppIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M1fke2lEPTB;Mj6wNlA1QSEQvF2=	MYTTRW5ITVJ?
GB-1	NH7jVHJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NF\z[IRKSzVyPUKuNFI2PzdizszN	MWXTRW5ITVJ?
RCC10RGB	MkjYS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NFfLWYNKSzVyPUKuNFQ5PzFizszN	MXnTRW5ITVJ?
SW954	NWnpRYFOT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M2ftN2lEPTB;Mj6wOVA{PiEQvF2=	NFzjWFZUSU6JRWK=
IST-MES1	Mn76S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M33lemlEPTB;Mj6wOVU3QCEQvF2=	M{D5cHNCVkeHUh?=
AU565	MkDyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NH3JVllKSzVyPUKuNFU6ODVizszN	NEnWb\|hUSU6JRWK=
CW-2	Ml\3S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M3\KNGlEPTB;Mj6wOlg4PSEQvF2=	MWfTRW5ITVJ?
TE-1	Ml\aS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MVLJR\|UxRTJwMEmzO\|ch\|ryP	M4P5SHNCVkeHUh?=
KP-4	MYrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NFrlPVVKSzVyPUKuNVA{OTJizszN	NG\JXnBUSU6JRWK=
SNU-C2B	NFzwR29Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NX3XblZ1UUN3ME2yMlExQDJ\|IN88US=>	MVXTRW5ITVJ?
NCI-H1395	MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MWfJR\|UxRTJwMUC5PFYh\|ryP	NF\PW\|VUSU6JRWK=
CAS-1	NVXFdFhwT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MX\JR\|UxRTJwMUG1OFYh\|ryP	M3HI[nNCVkeHUh?=
NCI-H1155	NV\3PVZ3T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NYL3W\|d1UUN3ME2yMlIzPjlizszN	MXXTRW5ITVJ?
SK-MEL-1	MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M3fUTWlEPTB;Mj6yPFE5OSEQvF2=	NHPnSmtUSU6JRWK=
KINGS-1	MXjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NVz4[o1NUUN3ME2yMlMxODh6IN88US=>	NXz1cnpZW0GQR1XS
ESS-1	NWHxcW11T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MVvJR\|UxRTJwM{C1NUDPxE1?	NED1e2dUSU6JRWK=
PANC-10-05	MmDVS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MkjHTWM2OD1{LkO3NFI1KM7:TR?=	Mlu4V2FPT0WU
HT-1376	MofXS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NWW3UmlWUUN3ME2yMlM5PzB6IN88US=>	MVjTRW5ITVJ?
LS-513	MXfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NHrmepVKSzVyPUKuN\|g5PzRizszN	NEfTe21USU6JRWK=
KNS-42	MV\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MXvJR\|UxRTJwM{mxNFUh\|ryP	NYnZO2V{W0GQR1XS
639-V	MmjvS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MmDyTWM2OD1{LkSyO\|U5KM7:TR?=	MX3TRW5ITVJ?
SJRH30	M4fZW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MVXJR\|UxRTJwNEWxOlEh\|ryP	NF:5eHFUSU6JRWK=
SW1783	MVPHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NXizRWF7UUN3ME2yMlQ4ODd6IN88US=>	M17tfnNCVkeHUh?=
NB6	MlnTS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MnXtTWM2OD1{LkS4Nlgh\|ryP	MWLTRW5ITVJ?
SK-MEL-30	NYHMclRXT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MUTJR\|UxRTJwNEi4N{DPxE1?	NXvoT\|lVW0GQR1XS
HCE-4	NITFXmFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				Mln5TWM2OD1{LkS5OFAzKM7:TR?=	M1:0bXNCVkeHUh?=
NB10	MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NXjkdJBMUUN3ME2yMlQ6PDJ7IN88US=>	M3TNR3NCVkeHUh?=
H-EMC-SS	Mo\hS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MX\JR\|UxRTJwNUS2OUDPxE1?	M{\4OnNCVkeHUh?=
SK-HEP-1	M4ewXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MX3JR\|UxRTJwNUWyN\|Yh\|ryP	Ml;BV2FPT0WU
HCC1395	MnnkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MmXrTWM2OD1{LkW1OlU2KM7:TR?=	NF;o[m9USU6JRWK=
HuCCT1	M3LGdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MVHJR\|UxRTJwNU[zPUDPxE1?	NIX5VpRUSU6JRWK=
SiHa	NEDvdYJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MYLJR\|UxRTJwNUi3NVkh\|ryP	MWTTRW5ITVJ?
EFO-21	Mn7LS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NHnVNpRKSzVyPUKuOVg4PjRizszN	M4HsUHNCVkeHUh?=
NCI-H1666	NG\vc4tIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MVTJR\|UxRTJwNUmwO\|Yh\|ryP	NVnzcFhtW0GQR1XS
UMC-11	NUfhVG9wT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NWjaZW9lUUN3ME2yMlU6QDZ6IN88US=>	NHq3dVJUSU6JRWK=
COLO-679	NHLGNpZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NFq5do5KSzVyPUKuOlEzOzNizszN	NFPFOoZUSU6JRWK=
A388	M3vDN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MVzJR\|UxRTJwNkWyOVMh\|ryP	M33FNXNCVkeHUh?=
LB2518-MEL	NEfa[o1Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NYDRVVJZUUN3ME2yMlY2PDB6IN88US=>	Mn\1V2FPT0WU
EW-13	MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NFTROFdKSzVyPUKuOlg4PjhizszN	MWrTRW5ITVJ?
MLMA	MVvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NGnlfI5KSzVyPUKuOlg5PTZizszN	NXvacZo1W0GQR1XS
HOP-92	NYGzbIpZT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MYHJR\|UxRTJwN{CxNUDPxE1?	NXn4fFhNW0GQR1XS
NOMO-1	MV3Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M{XpfWlEPTB;Mj63NVQ1OiEQvF2=	NFzZS3pUSU6JRWK=
NCI-H810	NYK4PIRjT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NVLV[oUzUUN3ME2yMlczOTl6IN88US=>	MV3TRW5ITVJ?
769-P	NHXnfmxIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				Mn;QTWM2OD1{LkeyNlgh\|ryP	NEHVSJVUSU6JRWK=
SAS	Mn\zS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NVXBT2lnUUN3ME2yMlc3PSEQvF2=	MlzXV2FPT0WU
M059J	MmHUS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NWHnbWZSUUN3ME2yMlc5OzF6IN88US=>	MV7TRW5ITVJ?
RD	M{\pVmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M1jt[mlEPTB;Mj63PVQ4OSEQvF2=	NF3qb\|RUSU6JRWK=
GT3TKB	M{CzXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NUn1OIdZUUN3ME2yMlg{PDN\|IN88US=>	MoSxV2FPT0WU
MZ7-mel	MnmxS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NHXCRVZKSzVyPUKuPFY2ODJizszN	NVThZ5NEW0GQR1XS
KYSE-510	NV7oS3ZkT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MlPrTWM2OD1{Lki5OVA1KM7:TR?=	NH7tRopUSU6JRWK=
NCI-N87	MonpS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MVrJR\|UxRTJwOUG4NFch\|ryP	MlvTV2FPT0WU
MKN1	NFvheZFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M2fx[GlEPTB;Mz6wNFE3OyEQvF2=	NHHjNJlUSU6JRWK=
NCI-H2170	M17Dc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M2LwZmlEPTB;Mz6wNFQ2OSEQvF2=	MVPTRW5ITVJ?
OVCAR-3	NE\4eYtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M134e2lEPTB;Mz6wNlEyPSEQvF2=	NXHFeohxW0GQR1XS
KLE	MXTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MkHxTWM2OD1\|LkC2PFEzKM7:TR?=	MX3TRW5ITVJ?
LB771-HNC	NYHIe5U3T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M4\XfmlEPTB;Mz6wPVM1OyEQvF2=	MWDTRW5ITVJ?
MC116	MkLES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NFXydplKSzVyPUOuNVEyOTJizszN	NHPmWHpUSU6JRWK=
SCC-9	Mn;xS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NF;Pc3lKSzVyPUOuNVE{PjZizszN	MX;TRW5ITVJ?
U031	M4[wWWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MUDJR\|UxRTNwMUK0NlMh\|ryP	NXqz[mdkW0GQR1XS
LCLC-103H	M3r1Xmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NHHv[lJKSzVyPUOuNlM5QTRizszN	MYDTRW5ITVJ?
U-266	NYj6R\|dwT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NUK0VZBCUUN3ME2zMlI4PjN\|IN88US=>	NVTaVXlyW0GQR1XS
JVM-2	M3PoXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NITBPGFKSzVyPUOuN\|IyPjRizszN	NEj3N\|ZUSU6JRWK=
UACC-257	M{PoW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M{nYfWlEPTB;Mz60OlQ{OSEQvF2=	NFPq[GVUSU6JRWK=
LB996-RCC	M3mzS2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MmrFTWM2OD1\|LkS2OVAzKM7:TR?=	MWfTRW5ITVJ?
BT-549	NV;hPVZET3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NHqxbFJKSzVyPUOuOVAzODlizszN	NVjVSIhyW0GQR1XS
NCI-H526	MliwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MmLITWM2OD1\|LkW0NVU5KM7:TR?=	MWHTRW5ITVJ?
RH-18	MV7Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MWLJR\|UxRTNwNkG3PVgh\|ryP	M{iwSHNCVkeHUh?=
SW626	M2PNXWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NEPibGJKSzVyPUOuO\|EyOjhizszN	Ml;FV2FPT0WU
SK-N-AS	NF3VNXJIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NHvFVpBKSzVyPUOuO\|MzPDdizszN	M3PaUHNCVkeHUh?=
IGR-1	NHHwcYNIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MknYTWM2OD1\|Lke0NlQ5KM7:TR?=	NFjFTIZUSU6JRWK=
NCI-H2291	M3TXdGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MVPJR\|UxRTNwN{WzN\|Yh\|ryP	M4PuNnNCVkeHUh?=
NCI-H441	Ml3lS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MWfJR\|UxRTNwOEK0N\|Mh\|ryP	NXXmUpdYW0GQR1XS
D-247MG	M33U[Wdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MlG4TWM2OD1\|Lki2NFMyKM7:TR?=	NXTXWId4W0GQR1XS
COLO-320-HSR	NYDCOI5NT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MmLtTWM2OD1\|LkmxNlcyKM7:TR?=	NW\vNWs5W0GQR1XS
A253	NIqzR5ZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M1W2TmlEPTB;Mz65NVQ{PiEQvF2=	MVLTRW5ITVJ?
HT55	NVrsXmFCT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NX7YbGczUUN3ME2zMlkyPzd\|IN88US=>	NHX1XIFUSU6JRWK=
MZ1-PC	MmnRS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MUjJR\|UxRTNwOUW4OlQh\|ryP	NV7sZ2szW0GQR1XS
RERF-LC-MS	NUnPN\|duT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M3\tVmlEPTB;Mz65OlUzPSEQvF2=	NFXBfnBUSU6JRWK=
SF268	M4PJN2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NWjCfWlNUUN3ME20MlEzQDhzIN88US=>	M2nOZXNCVkeHUh?=
RMG-I	NFvHS5JIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NWnJPVR[UUN3ME20MlIyPDV2IN88US=>	MlPFV2FPT0WU
CFPAC-1	MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MmDrTWM2OD12LkKxOlg2KM7:TR?=	M3eyT3NCVkeHUh?=
S-117	M2rmd2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NHrxXVFKSzVyPUSuNlIxOjRizszN	NV7HOHQzW0GQR1XS
NCI-H2122	NHTZ[lZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NES0UWJKSzVyPUSuN\|A6OzFizszN	NV7oOHdwW0GQR1XS
J82	M1;HNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				Mn\0TWM2OD12LkOzOFQyKM7:TR?=	MkXBV2FPT0WU
CAL-72	NX;0[YtGT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NUjGN\|RkUUN3ME20MlM2PDd5IN88US=>	MlrFV2FPT0WU
GP5d	MnLES5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NILUdmxKSzVyPUSuOFEzQThizszN	Mmi1V2FPT0WU
UACC-62	Mn7lS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				Mn33TWM2OD12LkS2OVQ2KM7:TR?=	M4\HeHNCVkeHUh?=
MS-1	M3nidmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MXfJR\|UxRTRwNEmxNVUh\|ryP	NIT5PVNUSU6JRWK=
RCM-1	NGTyVVVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NF;rXZdKSzVyPUSuOVI6OiEQvF2=	NYfMUJFpW0GQR1XS
IST-SL1	NV;5OWhxT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NHv5TppKSzVyPUSuOlU{PTlizszN	NX;GcG1bW0GQR1XS
SW756	M3PyW2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				Mm\UTWM2OD12Lk[5NVM2KM7:TR?=	NX72Om02W0GQR1XS
HCC38	MXvHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NGfaXIFKSzVyPUSuO\|EyQTdizszN	NH\uZWNUSU6JRWK=
YAPC	MlPQS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M1LS[WlEPTB;ND63NVMyOyEQvF2=	MVrTRW5ITVJ?
DK-MG	MmDCS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NH6zUWJKSzVyPUSuO\|gyOTJizszN	MlPUV2FPT0WU
HCC1937	MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				Ml\BTWM2OD12Lki1NVI2KM7:TR?=	M33qV3NCVkeHUh?=
OAW-28	NFjUN2pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NVnwN2h7UUN3ME20MlkzPDN3IN88US=>	MVvTRW5ITVJ?
MEG-01	MXnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NHH4TWtKSzVyPUWuNFg{OjhizszN	NUTuR2M6W0GQR1XS
GI-1	MWrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MoXjTWM2OD13LkKzOFg3KM7:TR?=	MVPTRW5ITVJ?
FADU	MULHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NELJd4ZKSzVyPUWuNlc5OzdizszN	M{TkNXNCVkeHUh?=
CAPAN-1	NVHTc297T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MY\JR\|UxRTVwM{m0N\|Ih\|ryP	MlfSV2FPT0WU
TGBC11TKB	MoT4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MWnJR\|UxRTVwNEW3PFYh\|ryP	MYHTRW5ITVJ?
DBTRG-05MG	MlHkS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NVz5V2tqUUN3ME21MlUxPTJizszN	NVr5c\|BbW0GQR1XS
ONS-76	NFz0VYpIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NIPIcHhKSzVyPUWuOVU5ODFizszN	Mn3LV2FPT0WU
Ca-Ski	NHXoWHZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MXrJR\|UxRTVwNkK1OlYh\|ryP	NFvicHpUSU6JRWK=
COLO-741	MVnHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MVTJR\|UxRTVwN{G5PVUh\|ryP	NGDpdmRUSU6JRWK=
HT-29	NEn2RYdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NGrqOIdKSzVyPUWuPFA1PzVizszN	M4DrcXNCVkeHUh?=
HCC1187	NHLQPJlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MYXJR\|UxRTVwOEGwNFgh\|ryP	NEjORWtUSU6JRWK=
Capan-2	M3[yWGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NUPOXFFZUUN3ME21Mlk2QTl2IN88US=>	NIW3VJNUSU6JRWK=
NCI-H630	M13Vc2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				Mn;TTWM2OD14LkGxOFQyKM7:TR?=	NXW1VnBtW0GQR1XS
COLO-678	MkmwS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MVfJR\|UxRTZwMUWwPVIh\|ryP	NEPpNIxUSU6JRWK=
D-502MG	MYDHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NYjNWW1lUUN3ME22MlE4OzN4IN88US=>	M4W4eHNCVkeHUh?=
NB17	NIfvc\|VIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NEnSS2NKSzVyPU[uNlQ6PDNizszN	MlzNV2FPT0WU
SK-MEL-24	NI\pVY9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NVj3eIg2UUN3ME22MlI3PDlizszN	M{\YTnNCVkeHUh?=
NCI-SNU-5	M{DkOWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MnXTTWM2OD14LkK3NVE5KM7:TR?=	M3XvV3NCVkeHUh?=
D-392MG	MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NW\QdWlxUUN3ME22MlM{Ozl7IN88US=>	NXLFdFhlW0GQR1XS
A498	NInoWWZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NFXE[FdKSzVyPU[uOFA{ODJizszN	MnXyV2FPT0WU
OCI-AML2	NEj2V5RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NVvrcY8xUUN3ME22MlQ2PDR3IN88US=>	NEHCNm9USU6JRWK=
HCC2157	NIrpVHBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				Mnr2TWM2OD14LkS1OlE3KM7:TR?=	NFj4THNUSU6JRWK=
C3A	NWfENWFQT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				Mo\UTWM2OD14LkWyNFA1KM7:TR?=	MoG4V2FPT0WU
NCI-H1650	Mnn0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NYXLOYJoUUN3ME22MlcxPTJ{IN88US=>	M3W5cnNCVkeHUh?=
DU-145	Mnu0S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M1fHOGlEPTB;Nj63O\|A{KM7:TR?=	MlLHV2FPT0WU
COLO-829	NF;yVotIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MkLPTWM2OD14Lke3PFc{KM7:TR?=	NUf4OHdwW0GQR1XS
LS-1034	MkjOS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MnzlTWM2OD15LkC0OFEzKM7:TR?=	NITXNWNUSU6JRWK=
HCC1954	MX\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M3HISmlEPTB;Nz60PFE{PCEQvF2=	M4G1XnNCVkeHUh?=
KURAMOCHI	M3TQOGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NF3WV\|ZKSzVyPUeuOFg2OzNizszN	MXHTRW5ITVJ?
Mo-T	MX;Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				Mk\hTWM2OD15LkWxOFk5KM7:TR?=	MUPTRW5ITVJ?
OE19	MXHHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M{XNNmlEPTB;Nz62OVUxOyEQvF2=	MXjTRW5ITVJ?
COR-L105	NIPySpdIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NH\TRnRKSzVyPUeuO\|E1OjFizszN	MXzTRW5ITVJ?
NCI-H2342	M3LEeGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M{TkeGlEPTB;Nz63NVUzOSEQvF2=	NFf4NFJUSU6JRWK=
U-87-MG	NGnLU2pIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NEfLfVBKSzVyPUiuNFM{OzRizszN	NHrVRVBUSU6JRWK=
MKN28	M1XVb2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MWLJR\|UxRThwMUG1NVUh\|ryP	NIi3RXdUSU6JRWK=
HT-1197	NY\MPWVtT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MojiTWM2OD16LkK1PVA4KM7:TR?=	NVqxb5RCW0GQR1XS
ChaGo-K-1	NI\iTHVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NV;TWFRSUUN3ME24MlM1OjR3IN88US=>	MUXTRW5ITVJ?
NCI-H226	MmPNS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NInmN5dKSzVyPUiuOFQ{OzFizszN	M2TxcXNCVkeHUh?=
NCI-H2029	M3nCPGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MXjJR\|UxRTlwME[3OVkh\|ryP	NGHkVXhUSU6JRWK=
TE-11	MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NGjKNW1KSzVyPUmuOFU2QDhizszN	M1fNVXNCVkeHUh?=
ZR-75-30	MlvPS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NHvFeYhKSzVyPUmuPVI3OzRizszN	MVHTRW5ITVJ?
SW837	NUPyfodDT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NVjr[plEUUN3ME2xNE4zOjl\|IN88US=>	NES1Z3hUSU6JRWK=
NCI-H1651	M4XkbWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NGTmSnVKSzVyPUGwMlI{OjZizszN	MlL0V2FPT0WU
NCI-H727	MnfyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NGDMSFRKSzVyPUGwMlQ1QTVizszN	NYPJfZhTW0GQR1XS
NCI-H358	NWLUWG9PT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				M{X3e2lEPTB;MUCuPFM3PSEQvF2=	NWr2c\|J{W0GQR1XS
NCI-H2087	MWjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MXXJR\|UxRTFzLkC0N\|Qh\|ryP	MkTkV2FPT0WU
FTC-133	M37pXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				NGf3V3pKSzVyPUGxMlQxPTFizszN	NEjHbpZUSU6JRWK=
LAN-6	Mn3nS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				MXvJR\|UxRTF{LkGyOEDPxE1?	NWTBTVdYW0GQR1XS
NCI-H1838	NWLreo1HT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NV[5OGpIUUN3ME2xNk42OTVzIN88US=>	NVz1SYVzW0GQR1XS
Calu-6	MWTHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MkDLTWM2OD1zND6xNFIyKM7:TR?=	NUjT[G1WW0GQR1XS
HCC70	MkeyS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NF7N[5ZKSzVyPUG0MlQ2OSEQvF2=	M3[xbHNCVkeHUh?=
KARPAS-299	NXLVWZBoT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NXPoUHVYUUN3ME2xOU4zOTV7IN88US=>	MWjTRW5ITVJ?
CAL-27	M{nMZ2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MUTJR\|UxRTF3LkO4OFMh\|ryP	M2jSXnNCVkeHUh?=
NCI-H82	M4ryPWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MWrJR\|UxRTF3LkWzNkDPxE1?	MUjTRW5ITVJ?
no-10	M{LMNWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				Mm\sTWM2OD1zNT65N\|gh\|ryP	M{fEd3NCVkeHUh?=
U251	NGO2UWZIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MnXNTWM2OD1zNj6zOlc2KM7:TR?=	M{WxOHNCVkeHUh?=
TE-9	NX3zfVFiT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MlX6TWM2OD1zNz61NVY3KM7:TR?=	M1TGTXNCVkeHUh?=
TE-10	MU\Hdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M3LiO2lEPTB;MUmuNFYxPyEQvF2=	M1XiZ3NCVkeHUh?=
COLO-824	NGLIXJBIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MYXJR\|UxRTJyLkmyO\|Yh\|ryP	M3XabnNCVkeHUh?=
HuP-T3	NFfObXlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MlXxTWM2OD1{MT6wO\|Q5KM7:TR?=	MlGxV2FPT0WU
KALS-1	MYjHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				M1TB[mlEPTB;MkGuNVc2KM7:TR?=	NF7oSopUSU6JRWK=
L-428	M1mxTWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MV;JR\|UxRTJzLkSwNVYh\|ryP	MWnTRW5ITVJ?
JAR	MXrHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MUDJR\|UxRTJzLkWwNkDPxE1?	M1uxTnNCVkeHUh?=
DoTc2-4510	NYXXNWVtT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NFTqUXJKSzVyPUKzMlg1PzVizszN	M3fMRnNCVkeHUh?=
ABC-1	NF;TRlRIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MWrJR\|UxRTJ4Lke5OVch\|ryP	NG[0fIxUSU6JRWK=
MHH-NB-11	NFT3fZhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M2DBPGlEPTB;M{OuN\|Q3PCEQvF2=	MWfTRW5ITVJ?
SW1463	NVnTXnZST3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NYHwOpR{UUN3ME2zN{46QDNizszN	NUPzSIpUW0GQR1XS
SW1417	NILSUGVIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NEnoVJJKSzVyPUO3MlA6PTJizszN	NIf4doxUSU6JRWK=
NB12	NHvt[\|dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NUjhRYdFUUN3ME2zPU41PjV3IN88US=>	NFPTSnNUSU6JRWK=
NY	M1myXmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MXvJR\|UxRTRzLkOyNFEh\|ryP	Mnu3V2FPT0WU
H1048	M3TSVWFxd3C2b4Ppd{BCe3OjeR?=	NYTQSWg6PTByIH7N	NWLWUpVtPzJiaB?=		M1HTVY5p[W6lZYOgRWJVNTJ4M,MAl4lv\HWlZXSgZZBweHSxc3nz	NEmwdHozPTd\|N{W0Ni=>
H86	M4nL[WFxd3C2b4Ppd{BCe3OjeR?=	M3fhdlUxOCCwTR?=	MYC3NkBp		NEO4XIxvcGGwY3XzJGFDXC1{NkRihLNqdmS3Y3XkJIFxd3C2b4Ppdy=>	M13aUlI2PzN5NUSy
H196	MWDBdI9xfG:\|aYOgRZN{[Xl?	M3\0fFUxOCCwTR?=	NV3MUFBVPzJiaB?=		MWLubIFv[2W\|IFHCWE0zPjQkgKPpcoR2[2WmIHHwc5B1d3Orcx?=	NIjZOpozPTd\|N{W0Ni=>
H446	NVi5Z4twSXCxcITvd4l{KEG\|c3H5	MW[1NFAhdk1?	NX\BTId7PzJiaB?=		NV[zOodjdmijbnPld{BCSlRvMk[z5qCUcW6mdXPl[EBieG:ydH;zbZM>	MWKyOVc{PzV2Mh?=
TFK-1	MXXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?		MVq3NkBp	NFjhV2pFVVOR	NV;HSoZjUUN3ME20O{BvVQ>?	M4L1XlI2OTV{MkS0
EGI-1	NH3VO2dIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=		NULN[YlFPzJiaB?=	NXL6dWlzTE2VTx?=	NGewdHNKSzVyPUWzJI5O	MoPVNlUyPTJ{NES=
OCI/AML3	MlHuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M3XTZlAvOiEQvF2=	NViyXJZRPDhiaB?=		MUflcohidmOnczDj[YxtKGe{b4f0bEBqdmirYnn0bY9vKGmwZIXj[YQh[nlic3XseY1mfGmwaXK=	NETsdlgzPDd\|OUO5Ny=>
U937	MlnjS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	M3zUWlAvOiEQvF2=	MlnUOFghcA>?		MkXz[Y5p[W6lZYOgZ4VtdCCpcn;3eIghcW6qaXLpeIlwdiCrbnT1Z4VlKGK7IIPlcJVu\XSrbnni	MkDSNlQ4Ozl\|OUO=
MOLM13	NGraN\|RIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	M2HKXFAvOiEQvF2=	MlPHOFghcA>?		M2TWW4VvcGGwY3XzJINmdGxiZ4Lve5RpKGmwaHnibZRqd25iaX7keYNm\CCkeTDz[Yx2dWW2aX7pZi=>	M4\neFI1PzN7M{mz
MCF7	NEHDU3NIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MlvQNlAhdk1?	NEPt[HA4OiCq	MnXSSmJU	MlzQdoVlfWOnczD0bIUhWEWOUEGtcYVlcWG2ZXSgbY5kemWjc3WgbY4h[2WubDD2bYFjcWyrdIm=	M13jdlI1Pjh6MES2
TamR	NGG4R\|FIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NWPnVpNpUUN3ME2xPQKBkW6P	NVXOeYtIOjR2NUewOlk>
MCF7-X	NUS5S2c3T3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				Mn:xTWM2OD1{NDDuUS=>	NVPNe4lQOjR2NUewOlk>
T47D-tamR	NVjDdJFTT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MXrJR\|UxRTF7IH7N	MlLxNlQ1PTdyNkm=
293T	MnjySpVv[3Srb36gRZN{[Xl?	MV:yNEBvVQ>?	M1HuWFMhcA>?		NV7rXnZy\Gm\|coXweJMhSWu2LX3l[IlifGWmIGTJSk1KSSC\|dHHibYxqfHluIITyZY5{dG:lYYTpc44tKGGwZDDhZ5Rqfmm2eR?=	NEO1fo8zPDN4M{S0PS=>
SW620	M3G2d2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MXWwMlAxOS1zMN88US=>	NUjGWnB[OjRiaB?=		NVLIXnZncW6qaXLpeJMhfGinIHPlcIwheHKxbHnm[ZJifGmxbjDhd{B1cGViY3;uZ4VvfHKjdHnvckBzcXOncx?=	NV3HTmhoOjR\|NkO0OFk>
Huh7	NFjlTlhIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MVu1MVExOCCwTR?=	MWCwMVI1KGh?	M2Pse2ROW09?	NHLNV4JqdmO{ZXHz[ZMh[2WubDDk[YF1cCCrbjDhJINwdmOnboTyZZRqd25vIHHu[EB1cW2nLXTldIVv\GWwdDDtZY5v\XJ?	NYTvO4hkOjR{OUezNFA>
Hep3B	M4G0d2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7	M3:5ZlUuOTByIH7N	M{LZflAuOjRiaB?=	MWDEUXNQ	NUHFPIFocW6lcnXhd4V{KGOnbHyg[IVifGhiaX6gZUBkd26lZX70doF1cW:wLTDhcoQhfGmvZT3k[ZBmdmSnboSgcYFvdmW{	MVmyOFI6PzNyMB?=
Huh7	MkjMSpVv[3Srb36gRZN{[Xl?	MYmxNFAhdk1?	M1i4WVEzKGh?	MoLsSG1UVw>?	NGm2OYNqdmS3Y3XzJIF2fG:yaHHnfeKh	MnqwNlQzQTd\|MEC=
U87-MG	MoK5S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?		M171U\|czKGh?		NV7Wb4k6T0l3MPMAjV3jiIl5OTDuUeKh	NG[wSIozPDJ2OU[0NC=>
L3.6pl	NHTt[XFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MnyyNUDPxE1?	NF7rU\|Y4OiCq		MlfrbY5pcWKrdIOgeIhmKGOnbHyg[5Jwf3SqIHPvcYJqdmWmIIfpeIghSk2VLUe3O\|YxPw>?	NHvIfVAzPDJ\|M{O5PS=>
TE671	M3n4RWFxd3C2b4Ppd{BCe3OjeR?=	M3\Bd\|Eh\|ryP	M{HOeFQ5KGh?		M{DqdIlv[3KnYYPld{Bk\WyuIHHwc5B1d3OrczDpcoR2[2WmIHL5JGFDXC15M{e=	MUOyOFE{OzJzOB?=
RD	NWXNSIkySXCxcITvd4l{KEG\|c3H5	MXOxJO69VQ>?	MXK0PEBp		NY\2WZd5cW6lcnXhd4V{KGOnbHygZZBweHSxc3nzJIlv\HWlZXSgZpkhSUKWLUezOy=>	NXi2ZmREOjRzM{OyNVg>
RMS13	MYnBdI9xfG:\|aYOgRZN{[Xl?	MnvDNUDPxE1?	NV;Gd41CPDhiaB?=		M3znZolv[3KnYYPld{Bk\WyuIHHwc5B1d3OrczDpcoR2[2WmIHL5JGFDXC15M{e=	NYXySlJFOjRzM{OyNVg>
RH30	NYnFSGFvSXCxcITvd4l{KEG\|c3H5	M3izVFEh\|ryP	M2nOWFQ5KGh?		M1vuV4lv[3KnYYPld{Bk\WyuIHHwc5B1d3OrczDpcoR2[2WmIHL5JGFDXC15M{e=	M3TNT\|I1OTN\|MkG4
Hep-2	NXfOZ2ZGT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=	MmjjNE4xOS1zIN88US=>	NHfUclEyOi17NjDo		M2L0PIlv[3KnYYPld{Bk\WyuIHTlZZRpKGmwIHGgZ49v[2WwdILheIlwdi1iYX7kJJRqdWVvZHXw[Y5l\W62IH3hco5meg>?	MVeyOFExOzd2OR?=
SCC-9	M2m1XGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7	MljlNE4xOS1zIN88US=>	MUixNk06PiCq		M1v1d4lv[3KnYYPld{Bk\WyuIHTlZZRpKGmwIHGgZ49v[2WwdILheIlwdi1iYX7kJJRqdWVvZHXw[Y5l\W62IH3hco5meg>?	MmDZNlQyODN5NEm=
Hep-2	NVv5eHUxTnWwY4Tpc44hSXO\|YYm=	NYfWWHFGOC5zL{CuOUDPxE1?	NFXW[lMzPCCq		NGniV\|VjdG:la4OgcXRQWkNzIHHu[EBuXE:UQ{KgZYN1cX[jdHnvci=>	Ml3uNlQyODN5NEm=
SCC-9	NFfFVlFHfW6ldHnvckBCe3OjeR?=	NHL4fGUxNjFxMD61JO69VQ>?	M{PWbVI1KGh?		MnexZoxw[2u\|IH3UU3JEOSCjbnSgcXRQWkN{IHHjeIl3[XSrb36=	M4e1[VI1OTB\|N{S5
PANC-1	NH7VeHlCeG:ydH;zbZMhSXO\|YYm=	M1O3S\|UxOCCwTR?=	NGXCfFc1QCCq		Mk\ud4Vve2m2aYrld{Bx[W6lcnXheIlkKGOjbnPldkBk\WyuczD0c{Bz[WSrb4To[ZJieHl?	NInye4QzOzh6NkK5OC=>
RMG2	M{\JdmFxd3C2b4Ppd{BCe3OjeR?=	M2nOdVEuOTByMDDuUS=>	MmDZO\|IhcA>?	NIXGfWRHSlN?	M4nlW4lvcGmkaYTzJJRp\SClZXzsJJZq[WKrbHn0fUBkd26lZX70doF1cW:wIHTldIVv\GWwdHz5	M2TtcVI{PjF3NkOx
HAC2	NWLhUpIxSXCxcITvd4l{KEG\|c3H5	Ml\ENU0yODByIH7N	MXy3NkBp	MkfKSmJU	M4L1folvcGmkaYTzJJRp\SClZXzsJJZq[WKrbHn0fUBkd26lZX70doF1cW:wIHTldIVv\GWwdHz5	MlHyNlM3OTV4M{G=
HT-29	NWLFRlk5SXCxcITvd4l{KEG\|c3H5	NIixVG8yKM7:TR?=	M360XlczKGh?		MWDheJRmdnWjdHXzJFUuTlVvaX7keYNm\CClZXzsJIRm[XSq	NVLhfotyOjF7NEmxNlE>
DLD1	NEfP[VBCeG:ydH;zbZMhSXO\|YYm=	NVPicGxPOSEQvF2=	Mn;qO\|IhcA>?		NEOzbXBifHSnboXheIV{KDVvRmWtbY5lfWOnZDDj[YxtKGSnYYTo	NUTZ[2dTOjF7NEmxNlE>
HT-29	MY\GeY5kfGmxbjDBd5NigQ>?	MX6xJO69VQ>?	MkXzO\|IhcA>?		NVnieFZncW6mdXPld{BifXSxcHjh[5khfG9iY3;u[oVzKGO7dH;wdo91\WO2aX;u	Mnq5NlE6PDlzMkG=
DLD1	MnHqSpVv[3Srb36gRZN{[Xl?	NF7jflMyKM7:TR?=	M3\VW\|czKGh?		NFq5VnlqdmS3Y3XzJIF2fG:yaHHnfUB1dyClb37m[ZIh[3m2b4Dyc5Rm[3Srb36=	MYWyNVk1QTF{MR?=
Rh41	M2XVdWdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MVLJR\|UxRTNyLkegcm0>	NXKzc3k{OjF\|M{e2O\|k>
Rh18	M1nMOmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MWLJR\|UxRTRzLkSgcm0>	NGS1NWkzOTN\|N{[3PS=>
Rh30	NIHYe3lIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NYfs[W13UUN3ME2xOEBvVQ>?	NITsUVgzOTN\|N{[3PS=>
BT-12	NGnDVZFIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NHy1NGNKSzVyPUK0Mlchdk1?	Mn;yNlE{Ozd4N{m=
CHLA-266	NUn2ZW9JT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MVfJR\|UxRTFwMTDuUS=>	MmrkNlE{Ozd4N{m=
TC-71	M4nRVGdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M{LJbWlEPTB;NE[uOUBvVQ>?	NVvCc5dGOjF\|M{e2O\|k>
CHLA-9	NVvSTYRsT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MXPJR\|UxRTF3LkOgcm0>	NFfFUYkzOTN\|N{[3PS=>
CHLA-10	MlnuS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				NWO3NXQ2UUN3ME2zMlkhdk1?	MXeyNVM{PzZ5OR?=
CHLA-258	MWLHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NGD1O2RKSzVyPUGwMlQhdk1?	MoLTNlE{Ozd4N{m=
GBM2	MYfHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				NXrCU\|J4UUN3ME20NE44KG6P	MYCyNVM{PzZ5OR?=
NB-1643	NUDQUYszT3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				NV2zZWNmUUN3ME2zN{45KG6P	NHTabngzOTN\|N{[3PS=>
NB-EBc1	M2D0dmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				MorOTWM2OD1{Nz6xJI5O	MmXFNlE{Ozd4N{m=
CHLA-90	NH;uRWlIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				M3TsRWlEPTB;M{SuOUBvVQ>?	NELU[4czOTN\|N{[3PS=>
CHLA-136	MkC4S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				M4HSOmlEPTB;MU[yMlYhdk1?	Mm\PNlE{Ozd4N{m=
NALM-6	MkLBS5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?				Mk[wTWM2OD1\|Mj65JI5O	NGfzfWQzOTN\|N{[3PS=>
COG-LL-317	MUXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MlLGTWM2OD1zLkOgcm0>	MYKyNVM{PzZ5OR?=
RS4;11	NXK2Rm1ET3Kxd4ToJGlvcGmkaYTpc44hSXO\|YYm=				MUXJR\|UxRTN3IH7N	MmjzNlE{Ozd4N{m=
MOLT-4	M2nV[2dzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M1rFWmlEPTB;OD62JI5O	M2LGNVIyOzN5Nke5
CCRF-CEM	M3q5dmdzd3e2aDDJcohq[mm2aX;uJGF{e2G7				M2XSW2lEPTB;ND6xJI5O	MlP6NlE{Ozd4N{m=
Kasumi-1	NEfsNWtIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				MVXJR\|UxRTFwNDDuUS=>	NX\YS4hEOjF\|M{e2O\|k>
Karpas-299	MWXHdo94fGhiSX7obYJqfGmxbjDBd5NigQ>?				MlnsTWM2OD1{MT63JI5O	NGHtXmozOTN\|N{[3PS=>
Ramos-RA1	NGPGdY9Iem:5dHigTY5pcWKrdHnvckBCe3OjeR?=				NWGyZolpUUN3ME24MlIhdk1?	M4\DOVIyOzN5Nke5
H838	MXTGeY5kfGmxbjDBd5NigQ>?	NEGyPIcyKM7:TR?=	MlLYOFghcA>?		Ml63bY5lfWOnczDj[YxtKGG3dH;wbIFogQ>?	NVjqUJZbOjB\|NkSxNVM>
H838	NHHnN\|BIem:5dHigTY5pcWKrdHnvckBCe3OjeR?=	MXewMVMh\|ryP	Moe2O\|IhcA>?		NWj3dpA2cW6mdXPld{Boem:5dHigbY5pcWKrdHnvckBidmRiYYX0c5Bp[We7	MYSyNFAzQDh3NB?=
A549	Mlz1S5Jwf3SqIFnubIljcXSrb36gRZN{[Xl?	Mkj5NE0{KM7:TR?=	MUm3NkBp		MnzQbY5lfWOnczDndo94fGhiaX7obYJqfGmxbjDhcoQh[XW2b4DoZYd6	M4C1ZlIxODJ6OEW0

... Click to View More Cell Line Experimental Data

In vivo

AZD8055 inhibits the pS6 and pAkt in U87MG and A549 xenografts at 2.5/10 mg/kg, which leads to tumor growth inhibition. AZD8055 shows significant antitumor activity in many xenografts, including U87MG, BT474c, A549, Calu-3, LoVo, SW620, PC3 and MES-SA at a dose of 10/20 mg/kg. ^[1] AZD8055 induces ~40% reduction in tumour volume, accompanied by ablation of phosphorylation of Akt, S6K and SGK protein kinases. Administration of AZD8055 (5mg/kg, Bid) and SAHA (100 mg/kg/d) results in complete tumor growth inhibition in PTEN+/−LKB1+/hypo xenografts without side effects on mice by inhibition of mTORC1 and mTORC2 signaling. ^[4]

Protocol

Kinase Assay:^[1]	+ Expand Cell-based determinations of mTOR inhibition: A high-throughput screening cell-based assay is developed using MDA-MB-468 cells to detect mTORC1 and mTORC2 activity. Cells are exposed for 2 hours to increasing concentrations of AZD8055. At the end of the incubation period, cells are fixed, washed, and probed with antibodies against S473 pAkt or against S235/236 phosphorylated S6 (pS6). Levels of phosphorylation are assessed using an Acumen laser scanning cytometer.
Cell Research:^[1]	+ Expand Cell lines: U87MG, A549 and H838 cells Concentrations: 1 nM - 1 μM Incubation Time: 72 to 96 hours Method: Cells are exposed to AZD8055 for 72 to 96 hours and stained for cell nuclei (0.03 mg/mL Hoechst 33342) and acidic vesicles (1 μg/mL acridine orange). Images are captured at 450 and 536 nm on an ArrayScan II platform, and the percentage of acidic vesicles and the number of cells are quantified. For LC3 assessment, cells are exposed to e64d/pepstatin (10 μg/mL) for 30 to 90 min before incubation with AZD8055. Cells are lysed on ice and analyzed by immunoblotting. (Only for Reference)
Animal Research:^[1]	+ Expand Animal Models: U87MG, BT474c, A549, Calu-3, LoVo, SW620, PC3 and MES-SA U87-MG and A549 are established in pathogen-free, female nude mice (nu/nu:Alpk). Formulation: Dissolved in captisol (CyDex, pH 3.0) and diluted to a final captisol concentration of 30% (w/v) Dosages: 2.5-20 mg/kg Administration: Oral gavage once or twice daily (Only for Reference)

References

[4] García-Martínez JM, et al. Br J Cancer, 2011, 104(7), 1116-1

+ Expand

Solubility (25°C)

In vitro	DMSO	50 mg/mL warmed (107.4 mM)
	Ethanol	3 mg/mL (6.44 mM)
	Water	Insoluble
In vivo	Add solvents to the product individually and in order(Data is from Selleck tests instead of citations): 4% DMSO+30% PEG 300+ddH2O For best results, use promptly after mixing.	5mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information Download AZD8055 SDF

Molecular Weight	465.54
Formula	C₂₅H₃₁N₅O₄
CAS No.	1009298-09-2
Storage	3 years -20°C powder
Storage	2 years -80°C in solvent
Synonyms	N/A

Bio Calculators

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration _(start) x Volume _(start) = Concentration _(final) x Volume _(final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

Serial Dilutions
Concertration (start):
Dilution-folds:

Computed Result

C1=C0/X	C1:	LOG(C1):
C2=C1/X	C2:	LOG(C2):
C3=C2/X	C3:	LOG(C3):
C4=C3/X	C4:	LOG(C4):
C5=C4/X	C5:	LOG(C5):
C6=C5/X	C6:	LOG(C6):
C7=C6/X	C7:	LOG(C7):
C8=C7/X	C8:	LOG(C8):

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2018-11-16)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT01316809	Completed	Glioblastoma Multiforme\|Anaplastic Astrocytoma\|Anaplastic Oligodendroglioma\|Malignant Glioma\|Brainstem Glioma	National Cancer Institute (NCI)\|National Institutes of Health Clinical Center (CC)	March 4 2011	Phase 1
NCT00999882	Completed	Cancer\|Advanced Hepatocellular Carcinoma	AstraZeneca	October 2009	Phase 1
NCT00973076	Completed	Cancer\|Solid Tumors\|Advanced Solid Malignancies	AstraZeneca	August 2009	Phase 1
NCT00731263	Completed	Solid Tumors	AstraZeneca	July 2008	Phase 1
NCT01194193	Withdrawn	Cancer\|Advanced Solid Tumours\|Lymphomas	AstraZeneca	null	Phase 1

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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mTOR Signaling Pathway Map

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AZD8055

Cited by 40 Publications

8 Customer Reviews

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Biological Activity

Protocol

References

Solubility (25°C)

Chemical Information Download AZD8055 SDF

Bio Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Dilution Calculator

Concentration _(start) x Volume _(start) = Concentration _(final) x Volume _(final)

The Serial Dilution Calculator Equation

Serial Dilutions

Computed Result

Molecular Weight Calculator

Total Molecular Weight: g/mol

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molarity Calculator

Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2018-11-16)

Tech Support

mTOR Signaling Pathway Map

mTOR Inhibitors with Unique Features

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AZD8055

Cited by 40 Publications

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Solubility (25°C)

Chemical Information Download AZD8055 SDF

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Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Dilution Calculator

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

The Serial Dilution Calculator Equation

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Molecular Weight Calculator

Total Molecular Weight: g/mol

Instructions to calculate molar mass (molecular weight) of a chemical compound:

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molarity Calculator

Clinical Trial Information (data from https://clinicaltrials.gov, updated on 2018-11-16)

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mTOR Signaling Pathway Map

mTOR Inhibitors with Unique Features

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Concentration _(start) x Volume _(start) = Concentration _(final) x Volume _(final)