| S1941 |
Enalapril Maleate
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Enalapril (MK-421) Maleate is an angiotensin-converting enzyme (ACE) inhibitor, used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure.
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J Immunother Cancer, 2024, 12(11)e009805
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BMC Pharmacol Toxicol, 2024, 25(1):25
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Molecules, 2022, 27(4)1417
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| S1733 |
Methylprednisolone
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Methylprednisolone is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. This compound activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. It markedly reduces autophagy and apoptosis.
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Food Chem Toxicol, 2024, 188:114665
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Drug Test Anal, 2020, 10.1002/dta.2917
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Nat Med, 2017, 23(4):424-428
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| S3981 |
Sinapinic Acid
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Sinapinic acid (Sinapic acid) is a small naturally occurring hydroxycinnamic acid which belongs to phenylpropanoid family and commonly used as matrix in MALDI mass spectrometry. Sinapinic acid (Sinapic acid) acts as an inhibitor of HDAC, with IC50 of 2.27 mM, and also inhibits ACE-I activity.
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Biochem Pharmacol, 2025, 241:117171
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ROYAL SOCIETY OF CHEMISTRY, 2023, 7, 2953-2973
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| S1793 |
Ramipril
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Ramipril (HOE-498) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 5 nM.
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J Immunother Cancer, 2024, 12(11)e009805
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| S2076 |
Lisinopril dihydrate
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Lisinopril dihydrate(MK-521 dihydrate) is an angiotensin-converting enzyme (ACE) inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks, and also in preventing renal and retinal complications of diabetes.
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J Immunother Cancer, 2024, 12(11)e009805
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| S2079 |
Moexipril HCl
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Moexipril HCl (RS-10085) is a potent orally active nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor, used for the treatment of hypertension and congestive heart failure.
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J Cell Biochem, 2022, 10.1002/jcb.30213
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| S2109 |
Imidapril HCl
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Imidapril HCl(TA-6366) is an angiotensin-converting enzyme (ACE) inhibitor with IC50 of 2.6 nM, used for the treatment of hypertension.
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J Immunother Cancer, 2024, 12(11)e009805
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| S6468 |
Trandolapril
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Trandolapril(RU44570) is a newly developed angiotensin-converting enzyme (ACE) inhibitor that is rapidly hydrolyzed mainly in the liver to its biologically active metabolite trandolaprilat.
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J Immunother Cancer, 2024, 12(11)e009805
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| S2095 |
Fosinopril Sodium
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Fosinopril Sodium (SQ28555) is the ester prodrug of an angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension and some types of chronic heart failure.
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J Immunother Cancer, 2024, 12(11)e009805
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| S9820 |
Angiotensin (1-7)
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Angiotensin (1-7) (Ang-(1-7), Angiotensin fragment 1-7) is a bioactive component of the renin-angiotensin system that is formed endogenously from either Ang I or Ang II. This compound is a canine ACE inhibitor with an IC50 of 0.65 μM and inhibits the activity mediated by myostatin through Mas receptor.
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Int J Biol Sci, 2023, 19(8):2613-2629
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| S2100 |
Temocapril
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Temocapril (CS-622,temocaprilum) is a long-acting angiotensin-converting enzyme (ACE) inhibitor, used for the treatment of hypertension.
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| S5728 |
Delapril Hydrochloride
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Delapril Hydrochloride (Alindapril) is the hydrochloride salt form of delapril, which is a lipophilic, non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
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| S5973 |
Methylprednisolone Acetate
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Methylprednisolone (NSC-19987, Medrol) acetate is a synthetic glucocorticoid receptor agonist, used to achieve prompt suppression of inflammation. Methylprednisolone activates ACE2 and reduces IL-6 levels, thus improves severe or critical COVID-19. Methylprednisolone markedly reduces autophagy and apoptosis.
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