- Substance P Inhibitors (2)
|Catalog No.||Information||Product Use Citations||Product Validations|
Aprepitant is a potent and selective neurokinin-1 receptor antagonist with IC50 of 0.1 nM.
HepT1, HepG2, and HuH6 cells were treated with increasing doses of aprepitant or SP [100 nM] and Western blot analysis was performed for the apoptotic markers PARP, Caspase-3, and BID.
Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity.