Ropivacaine HCl
Catalog No.S4058 Synonyms: LEA-103 HCl
Molecular Weight(MW): 310.86
Ropivacaine HCl is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly.
Purity & Quality Control
Choose Selective Sodium Channel Inhibitors
Biological Activity
| Description | Ropivacaine HCl is an anaesthetic agent and blocks impulse conduction in nerve fibres through inhibiting sodium ion influx reversibly. |
|---|---|
| In vitro |
Ropivacaine HCl is a local anaesthetic agent. Ropivacaine HCl elicits nerve block via reversible inhibition of sodium ion influx in nerve fibres. The pKa of ropivacaine HCl is ~8.2. Ropivacaine HCl has the potential to induce cardiovascular toxicity and CNS toxicity at high plasma concentrations. [1] |
Protocol
Solubility (25°C)
| In vitro | DMSO | 62 mg/mL (199.44 mM) |
|---|---|---|
| Water | 46 mg/mL (147.97 mM) | |
| Ethanol | Insoluble |
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Information
| Molecular Weight | 310.86 |
|---|---|
| Formula | C17H26N2O.HCl |
| CAS No. | 132112-35-7 |
| Storage | powder |
| Synonyms | LEA-103 HCl |
Bio Calculators
Molarity Calculator
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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).
Dilution Calculator
Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:
Concentration (start) x Volume (start) = Concentration (final) x Volume (final)
This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )
* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).
Molecular Weight Calculator
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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Molarity Calculator
Clinical Trial Information
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT03038425 | Not yet recruiting | Arthroplasty, Replacement, Knee|Nerve Block|Anesthesia, Regional|Ambulatory Surgical Procedures | Ottawa Hospital Research Institute|The Ottawa Hospital Academic Medical Association | March 2017 | -- |
| NCT03023462 | Not yet recruiting | Inguinal Hernia|Pain, Postoperative | Ostfold Hospital Trust | February 2017 | Phase 4 |
| NCT03046290 | Recruiting | Regional Anesthesia|Postoperative Pain|Circumcision | Université Libre de Bruxelles | January 2017 | -- |
| NCT02857465 | Not yet recruiting | Obstetric Pain|Other Complications of Obstetric Anesthesia - Delivered | Centre Hospitalier Universitaire de la Réunion | January 2017 | Phase 3 |
| NCT02950558 | Not yet recruiting | Chronic Pain|Ankle Fracture Surgery|Regional Anesthesia | University of Cincinnati | January 2017 | Phase 2 |
| NCT03011905 | Not yet recruiting | Brachial Plexus Block|Pain, Postoperative | Oslo University Hospital | January 2017 | Phase 3 |
Tech Support
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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