Tolperisone HCl
Catalog No.S4200
Molecular Weight(MW): 281.82
Tolperisone HCl is an ion channel blocker and centrally-acting muscle relaxant.
Purity & Quality Control
Choose Selective Sodium Channel Inhibitors
Biological Activity
| Description | Tolperisone HCl is an ion channel blocker and centrally-acting muscle relaxant. | |
|---|---|---|
| Targets |
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| In vitro |
Tolperisone reduces sodium and potassium permeability in the node of Ranvier of frogs, blocks calcium currents in snail neurons and inhibits current through heterologously expressed Nav1.6 channels. [1] Tolperisone hydrochloride represents an effective and safe treatment of painful reflex muscle spasm without the typical side effects of centrally active muscle relaxants. [2] |
Protocol
Solubility (25°C)
| In vitro | DMSO | 56 mg/mL (198.7 mM) |
|---|---|---|
| Water | 56 mg/mL (198.7 mM) | |
| Ethanol | 56 mg/mL (198.7 mM) |
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Information
| Molecular Weight | 281.82 |
|---|---|
| Formula | C16H23NO.HCl |
| CAS No. | 3644-61-9 |
| Storage | powder |
| Synonyms | N/A |
Bio Calculators
Molarity Calculator
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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).
Dilution Calculator
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This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )
* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).
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Molarity Calculator
Clinical Trial Information
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT00532532 | Terminated | Muscle Spasticity | Avigen | September 2007 | Phase 2 |
| NCT00531466 | Terminated | Muscle Spasticity | Avigen | September 2007 | Phase 2 |
Tech Support
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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