For research use only. Not for use in humans.

Ongericimab (Anti-PCSK9)

Synonyms: JS002 Cat.No.A2987

Ongericimab (Anti-PCSK9) is a humanized monoclonal antibody targeting PCSK9. It has lipid-lowering efficacy and can be used in research of hypercholesteremia and hyperlipidemia. MW :143.04 KD.

Ongericimab (Anti-PCSK9)

Quality Control

Specificity

Name	Citation	PCSK9
PF-06446846	0	+++
PF-06446846 hydrochloride	0	✔
SBC-110736	0	✔
R-IMPP	0	✔
SBC-115076	9	✔

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Ongericimab (Anti-PCSK9) is a humanized monoclonal antibody targeting PCSK9. It has lipid-lowering efficacy and can be used in research of hypercholesteremia and hyperlipidemia. MW :143.04 KD.
References	https://www.ahajournals.org/doi/10.1161/circ.146.suppl_1.10921

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

CAS No.	2145096-91-7
Molecular Weight	143.04
Isotype	Human IgG4SP
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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