Loncastuximab tesirine | CD markers inhibitor | Read Reviews & Product Use Citations

Loncastuximab tesirine (ADCT-402, RB4v1.2-SG-3249) is an antibody-drug conjugate (ADC) composed of an anti-CD19 (B lymphocyte surface antigen B4, Leu-12) chimeric monoclonal antibody , conjugated to Pyrrolobenzodiazepine (PDB) dimer SCX, via a cleavable (valine-alanine dipeptide as cathepsine B cleavage site) maleimide type linker containing a spacer PEG.

CAS No. 1879918-31-6

Purity & Quality Control

≥99

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Biological Activity

Description	Loncastuximab tesirine (ADCT-402, RB4v1.2-SG-3249) is an antibody-drug conjugate (ADC) composed of an anti-CD19 (B lymphocyte surface antigen B4, Leu-12) chimeric monoclonal antibody , conjugated to Pyrrolobenzodiazepine (PDB) dimer SCX, via a cleavable (valine-alanine dipeptide as cathepsine B cleavage site) maleimide type linker containing a spacer PEG.

References
[1] Furqan F, et al. Ther Adv Hematol. 2022 Mar 22;13:20406207221087511.

References

[1] Furqan F, et al. Ther Adv Hematol. 2022 Mar 22;13:20406207221087511.

Product Details

CAS No.	1879918-31-6
ADC antiody	Loncastuximab
ADC cytotoxin	Tesirine
Formulation	1xPBS
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

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