Home Immunology & Inflammation NOS inhibitor L-Canavanine sulfate For research use only.

L-Canavanine sulfate

L-Canavanine sulfate is a selective inhibitor of inducible NO synthase. L-Canavanine sulfate exhibits IC50 values ranging from 5 to 10 mM in arginine-rich media and causes a limited degree of cytotoxicity in HeLa, Hep G2, and SK-HEP-1 cells.

L-Canavanine sulfate Chemical Structure

L-Canavanine sulfate Chemical Structure

CAS: 2219-31-0

Purity & Quality Control

Batch: Purity: 100.00%
100.00

L-Canavanine sulfate Related Products

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Biological Activity

Description L-Canavanine sulfate is a selective inhibitor of inducible NO synthase. L-Canavanine sulfate exhibits IC50 values ranging from 5 to 10 mM in arginine-rich media and causes a limited degree of cytotoxicity in HeLa, Hep G2, and SK-HEP-1 cells.
Targets
NO synthase [1]
5mM

Chemical Information & Solubility

Molecular Weight 274.25 Formula

C5H12N4O3.H2O4S
CAS No. 2219-31-0 SDF Download L-Canavanine sulfate SDF
Storage (From the date of receipt) Solutions are unstable. Prepare fresh or purchase small, pre-packaged sizes. Repackage upon receipt.

In vitro
Batch:

Water : 55 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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