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Elezanumab (Anti-RGMA)
Synonyms: ABT-555, AE12-1Y-QL
Elezanumab (Anti-RGMA) is a human monoclonal antibody that selectively targets repulsive guidance molecule A (RGMa). Elezanumab potently inhibited RGMa mediated BMP signalling via the SMAD1/5/8 pathway with IC50 of 97 pM. MW: 146.44 kD.
Purity & Quality Control
Choose Selective TGF-beta/Smad Inhibitors
Biological Activity
| Description | Elezanumab (Anti-RGMA) is a human monoclonal antibody that selectively targets repulsive guidance molecule A (RGMa). Elezanumab potently inhibited RGMa mediated BMP signalling via the SMAD1/5/8 pathway with IC50 of 97 pM. MW: 146.44 kD. |
|---|
Product Details
| CAS No. | 1791416-49-3 |
|---|---|
| Molecular Weight | 146.44 kDa |
| Isotype | Human IgG1 |
| Source | CHO |
| Purification | AKTA |
| Sterility | 0.2 μM filtered |
| Formulation | 100mMPro-Ac,20mMArg-Ac，pH5.0 |
| Storage (From the date of receipt) |
Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles. |
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