Datopotamab deruxtecan | Antibody-Drug Conjugate inhibitor | Read Reviews & Product Use Citations

Datopotamab deruxtecan (DS-1062, DS-1062A, Anti-TRP2/dxd) is an antibody-drug conjugate (ADC) composed of a humanized anti-TROP2 monoclonal antibody, conjugated to topoisomerase I inhibitor, via a tetrapeptide-based linker. Datopotamab deruxtecan has the potential for use in solid tumors mainly in advanced unresectable advanced NSCLC.

CAS No. 2238831-60-0

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Purity & Quality Control

Batch: D405001 Purity: 98.31% Protein concentration: 2.85mg/ml Endotoxin Level: ＜1EU/mg

98.31

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Biological Activity

Description	Datopotamab deruxtecan (DS-1062, DS-1062A, Anti-TRP2/dxd) is an antibody-drug conjugate (ADC) composed of a humanized anti-TROP2 monoclonal antibody, conjugated to topoisomerase I inhibitor, via a tetrapeptide-based linker. Datopotamab deruxtecan has the potential for use in solid tumors mainly in advanced unresectable advanced NSCLC.

References
[1] Okajima D, et al. Mol Cancer Ther. 2021 Dec;20(12):2329-2340.

References

[1] Okajima D, et al. Mol Cancer Ther. 2021 Dec;20(12):2329-2340.

Product Details

CAS No.	2238831-60-0
DAR	4.2
ADC antiody	Datopotamab
ADC linker	A tetrapeptide-based linker
ADC cytotoxin	Dxd
Formulation	1xPBS
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

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