For research use only. Not for use in humans.

Anti-PCSK9 (Boehringer anti-PCSK9)

Synonyms: null Cat.No.A2789

Anti-PCSK9 (Boehringer anti-PCSK9) is a monoclonal antibody against proprotein convertase subtilisin/kexin type 9 (PCSK9) that prevents PCSK9-mediated degradation of the LDLR.MW: 146.42 kD.

Anti-PCSK9 (Boehringer anti-PCSK9)

Quality Control

Specificity

Name	Citation	PCSK9
PF-06446846	0	+++
PF-06446846 hydrochloride	0	✔
SBC-110736	0	✔
R-IMPP	0	✔
SBC-115076	9	✔

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1. "+" indicates inhibitory effect. Increased inhibition is marked by a higher "+" designation. 2. "✔" indicates inhibitory effect, but without specific value.

Mechanism of Action

Description	Anti-PCSK9 (Boehringer anti-PCSK9) is a monoclonal antibody against proprotein convertase subtilisin/kexin type 9 (PCSK9) that prevents PCSK9-mediated degradation of the LDLR.MW: 146.42 kD.
References	https://pubmed.ncbi.nlm.nih.gov/24252255/

Cell Lines	Assay Type	Concentration	Incubation Time	Formulation	Activity Description	PMID

Product Details

Molecular Weight	146.42
Isotype	Human IgG1
Source	CHO
Purification	AKTA
Sterility	0.2 μM filtered
Formulation	100 mM Pro-Ac, 20mM Arg, pH5.0
Storage (From the date of receipt)	Store the undiluted solution at -20°C in the dark to avoid freeze-thaw cycles.

Comparison of Clones for

^*Literature analysis of various clone (for this target) products available on the market shows that Selleck's selected clones are more frequently applied. (data until September 2024)

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