Catalog No.S2525 Synonyms: Diphenylhydantoin

Phenytoin Chemical Structure

Molecular Weight(MW): 252.27

Phenytoin is an inactive voltage-gated sodium channel stabilizer.

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In DMSO USD 130 In stock
USD 97 In stock
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Biological Activity

Description Phenytoin is an inactive voltage-gated sodium channel stabilizer.
Sodium channel [1]


Solubility (25°C)

In vitro DMSO 50 mg/mL (198.2 mM)
Ethanol 13 mg/mL (51.53 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 252.27


CAS No. 57-41-0
Storage powder
in solvent
Synonyms Diphenylhydantoin

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

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Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

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This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

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Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02939937 Recruiting Optic Neuritis Tehran University of Medical Sciences July 2016 Phase 2
NCT02707965 Not yet recruiting Epilepsy Food and Drug Administration (FDA)|University of Maryland March 2016 --
NCT01960075 Recruiting Benzodiazepine Refractory Status Epilepticus University of Virginia|University of Michigan|Medical University of South Carolina|Childrens Research Institute|University of Minnesota - Clinical and Translational Science Institute|National Institute of Neurological Disorders and Stroke (NINDS) October 2015 Phase 3
NCT02595723 Completed Cognitive Impairment University of Texas Southwestern Medical Center|The Rogosin Institute July 2015 Early Phase 1
NCT02413658 Recruiting Wound|Re-Epithelialization Childrens Surgical Center, Cambodia March 2015 Phase 2
NCT02374567 Recruiting Dementia|Depression|Schizophrenia|Psychosomatic Disorders|Anxiety Disorders Hannover Medical School January 2015 Phase 3

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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Sodium Channel Signaling Pathway Map

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