Oxcarbazepine

Catalog No.S1391 Synonyms: GP47680

Oxcarbazepine Chemical Structure

Molecular Weight(MW): 252.27

Oxcarbazepine inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 μM and also inhibits the influx of 22Na+ into rat brain synaptosomes with IC50 about 100 μM.

Size Price Stock Quantity  
In DMSO USD 130 In stock
USD 97 In stock
USD 310 In stock
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Biological Activity

Description Oxcarbazepine inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 μM and also inhibits the influx of 22Na+ into rat brain synaptosomes with IC50 about 100 μM.
Targets
sodium channel [1]
160 μM

Protocol

References

Solubility (25°C)

In vitro DMSO 7 mg/mL (27.74 mM)
Water Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 252.27
Formula

C15H12N2O2

CAS No. 28721-07-5
Storage powder
Synonyms GP47680

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02078089 Terminated Cancer Costantine Albany|Indiana University March 6, 2014 Phase 1
NCT02893371 Not yet recruiting Bipolar Disorder University of New Mexico|Patient-Centered Outcomes Research Institute|Montana State University|National Alliance on Mental Illness|CGStat LLC|Risk Benefit Statistics LLC September 2016 --
NCT02705768 Recruiting Seizures, Focal All India Institute of Medical Sciences, Bhubaneswar April 2016 Phase 4
NCT02456896 Completed Bipolar Disorder All India Institute of Medical Sciences, Bhubaneswar June 2015 Phase 4
NCT02374567 Recruiting Dementia|Depression|Schizophrenia|Psychosomatic Disorders|Anxiety Disorders Hannover Medical School January 2015 Phase 3
NCT02104661 Recruiting Multiple Sclerosis Queen Mary University of London|National Multiple Sclerosis Society|Novartis Pharmaceuticals|Barts & The London NHS Trust|University College, London|Royal Free Hospital NHS Foundation Trust|Southend University Hospital|Basildon and Thurrock University Hospitals NHS Foundation Trust|St Georges Healthcare NHS Trust|Barnet and Chase Farm Hospitals NHS Trust October 2014 Phase 2

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Sodium Channel Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID