Oxcarbazepine
Catalog No.S1391 Synonyms: GP47680
Molecular Weight(MW): 252.27
Oxcarbazepine inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 μM and also inhibits the influx of 22Na+ into rat brain synaptosomes with IC50 about 100 μM.
Purity & Quality Control
Choose Selective Sodium Channel Inhibitors
Biological Activity
| Description | Oxcarbazepine inhibits the binding of [3H]BTX to sodium channels with IC50 of 160 μM and also inhibits the influx of 22Na+ into rat brain synaptosomes with IC50 about 100 μM. | ||
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Protocol
References
Solubility (25°C)
| In vitro | DMSO | 7 mg/mL (27.74 mM) |
|---|---|---|
| Water | Insoluble | |
| Ethanol | Insoluble |
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Information
| Molecular Weight | 252.27 |
|---|---|
| Formula | C15H12N2O2 |
| CAS No. | 28721-07-5 |
| Storage | powder |
| Synonyms | GP47680 |
Bio Calculators
Molarity Calculator
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Definitions of molecular mass, molecular weight, molar mass and molar weight:
Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.
Molarity Calculator
Clinical Trial Information
| NCT Number | Recruitment | Conditions | Sponsor/Collaborators | Start Date | Phases |
|---|---|---|---|---|---|
| NCT02078089 | Terminated | Cancer | Costantine Albany|Indiana University | March 6, 2014 | Phase 1 |
| NCT02893371 | Not yet recruiting | Bipolar Disorder | University of New Mexico|Patient-Centered Outcomes Research Institute|Montana State University|National Alliance on Mental Illness|CGStat LLC|Risk Benefit Statistics LLC | September 2016 | -- |
| NCT02705768 | Recruiting | Seizures, Focal | All India Institute of Medical Sciences, Bhubaneswar | April 2016 | Phase 4 |
| NCT02456896 | Completed | Bipolar Disorder | All India Institute of Medical Sciences, Bhubaneswar | June 2015 | Phase 4 |
| NCT02374567 | Recruiting | Dementia|Depression|Schizophrenia|Psychosomatic Disorders|Anxiety Disorders | Hannover Medical School | January 2015 | Phase 3 |
| NCT02104661 | Recruiting | Multiple Sclerosis | Queen Mary University of London|National Multiple Sclerosis Society|Novartis Pharmaceuticals|Barts & The London NHS Trust|University College, London|Royal Free Hospital NHS Foundation Trust|Southend University Hospital|Basildon and Thurrock University Hospitals NHS Foundation Trust|St Georges Healthcare NHS Trust|Barnet and Chase Farm Hospitals NHS Trust | October 2014 | Phase 2 |
Tech Support
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.
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