Nefiracetam(Translon) Chemical Structure
Dutasteride is a 5-alpha-reductase inhibitor
Tandutinib (MLN518) is a FLT3 inhibitor. In cell-based assays tandutinib inhibited FLT3, PDGFR and KIT with IC50 values of 95-122 ng/mL.
Bax inhibitor peptide P5 is a cell-permeable synthetic Bax peptide inhibitor.
Bax inhibitor peptide V5 is a cell-permeable synthetic Bax peptide inhibitor.
Pkc Inhibitor
NPI-2358 is a novel vascular disrupting agent (VDA) with an IC50 of 15 nM against HT-29 cells.
ENMD-2076 is a antiangiogenic and Aurora kinase inhibitor with IC50 of 3, 13, 350, 23, 40, 93 and 120 nM for Flt-3, AurA, AurB, Src, KDR/VEGFR2 and FGFR1.
2-methoxyestradiol is a natural metabolite of estrogen that is known to inhibit HIF-1 alpha with an IC50 of 0.71 ± 0.11 μM for the inhibition of BPAEC migration.
PD173074 is a potent ATP-competitive, reversible FGFR and VEGFR inhibitor with IC50 of 5, 21.5 and ~100 nM for FGFR3, FGFR1 and VEGFR2, respectively.
SQ109 is an orally active, small molecule antibiotic for treatment of pulmonary TB(tuberculosis).
Nefiracetam(Translon) is cognitive enhancer with an IC50 of approximately 150–200 μM for Ro 5-4864. It displays various pharmacological effects. It activates L/N-type calcium channels, cholinergic, monoaminergic and GABAergic systems. It displays potent neuroprotective action in the retinal ischemia-reperfusion model in vivo. [1][2]
| Molecular Weight (WM): | 246.3 |
|---|---|
| Formula: | C14H18N2O2 |
| CAS No.: | 77191-36-7 |
| Synonyms: |
DM 9384, Translon, DZL-221
|
| Dissolve in (25°C): | DMSO ≥49mg/mL |
| Water ≥5mg/mL | |
| Ethanol ≥49mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
A collection of 864 bioactive compounds
A collection of 481 inhibitors
A collection of 194 kinase inhibitors
A collection of 85 tyrosine kinase inhibitors.
A collection of 426 FDA approved drugs
A collection of 139 natural products
A collection of 40 chemotherapeutic agents
A unique collection of 17 small molecule modulators
A unique collection of 47 small molecule inhibitors
A unique collection of 63 GPCR small molecules
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