Catalog No.S4270

Oxiracetam, a cyclic derivative of gamma-aminobutyric acid (GABA), is used as a nootropic drug to improve memory and learning.

Price Stock Quantity  
USD 237 In stock
USD 829 In stock
Bulk Inquiry

Massive Discount Available

Free Overnight Delivery on all orders over $ 500.

Oxiracetam Chemical Structure

Oxiracetam Chemical Structure
Molecular Weight: 158.16

Validation & Quality Control

Quality Control & MSDS

Related Compound Libraries

Oxiracetam is available in the following compound libraries:

Product Information

  • Compare GABA Receptor Inhibitors
    Compare GABA Receptor Products
  • Research Area

Product Description

Biological Activity

Description Oxiracetam, a cyclic derivative of gamma-aminobutyric acid (GABA), is used as a nootropic drug to improve memory and learning.
In vitro
In vivo Oxiracetam (50 mg/kg i.p.) improves avoidance acquisition in BALB/c mice. [1] Oxiracetam (100 mg/kg i.p.) reduces the scopolamine-induced amnesic effect and decrease in acetylcholine level in the cortex and hippocampus. [2] Oxiracetam pretreatment (30 mg/kg) prevents social recognition deficits produced with trimethyltin in rats. [3]

Protocol(Only for Reference)

Animal Study: [1]

Animal Models BALB/c mice
Dosages 50 mg/kg
Administration i.p.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)

SpeciesMouseRatRabbitGuinea pigHamsterDog
Weight (kg)
Body Surface Area (m2)0.0070.0250.
Km factor36128520
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Rat dose (mg/kg) = mouse dose (22.4 mg/kg) ×  mouse Km(3)  = 11.2 mg/kg
rat Km(6)


[1] Sansone M, et al. Arch Int Pharmacodyn Ther. 1985, 275(1), 86-92.

[2] Spignoli G, et al. Pharmacol Biochem Behav. 1987, 27(3), 491-495.

view more

Chemical Information

Download Oxiracetam SDF
Molecular Weight (MW) 158.16


CAS No. 62613-82-5
Storage 3 years -20℃powder
2 years -80℃in solvent
Synonyms ISF 2522
Solubility (25°C) * In vitro DMSO 31 mg/mL (196.0 mM)
Water 31 mg/mL (196.0 mM)
Ethanol <1 mg/mL
In vivo
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Chemical Name 4-Hydroxy-2-oxopyrrolidine-N-acetamide

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

* Indicates a Required Field

Related GABA Receptor Products

  • AZD3839

    AZD3839 is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. Phase 1.

  • Xanthohumol

    Xanthohumol, a prenylated chalcone from hop, inhibits COX-1 and COX-2 activity and shows chemopreventive effects. Phase 1.

  • A-438079 HCl

    A-438079 HCl is a potent, and selective P2X7 receptor antagonist with pIC50 of 6.9.

  • (+)-Bicuculline

    (+)-Bicuculline is a competitive antagonist of GABAA receptors with IC50 of 2 μM, also blocks Ca(2+)-activated potassium channels.

  • Flumazenil

    Flumazenil is a competitive GABAA receptor antagonist, used in the treatment of benzodiazepine overdoses.

  • Gabapentin

    Gabapentin is a GABA analogue, used to treat seizures and neuropathic pain.

  • Baicalin

    Baicalin is a known prolyl endopeptidase inhibitor and affects the GABA receptors.

  • Gabapentin HCl

    Gabapentin HCl is a GABA analogue, used to treat seizures and neuropathic pain.

  • Dihydromyricetin

    Dihydromyricetin (Ampelopsin, Ampeloptin) is a natural antioxidant flavonoid from Ampelopsis grossedentata.

  • (R)-baclofen

    (R)-baclofen is a derivative of gamma-aminobutyric acid primarily used to treat spasticity.

Recently Viewed Items

Tags: buy Oxiracetam | Oxiracetam supplier | purchase Oxiracetam | Oxiracetam cost | Oxiracetam manufacturer | order Oxiracetam | Oxiracetam distributor
Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID
Contact Us